NLRP2

An Error has occured retrieving Wikidata item for infobox NLRP2‏ (NLR family pyrin domain containing 2) هوَ بروتين يُشَفر بواسطة جين NLRP2 في الإنسان.^[1]^[2]^[3]^[1]

الوظيفة

الأهمية السريرية

المراجع

^ ^أ ^ب "Entrez Gene: NLRP2 NLR family, pyrin domain containing 2". مؤرشف من الأصل في 2010-12-05.
^ Tschopp J، Martinon F، Burns K (فبراير 2003). "NALPs: a novel protein family involved in inflammation". Nat Rev Mol Cell Biol. ج. 4 ع. 2: 95–104. DOI:10.1038/nrm1019. PMID:12563287.
^ Bertin J، DiStefano PS (مارس 2001). "The PYRIN domain: a novel motif found in apoptosis and inflammation proteins". Cell Death Differ. ج. 7 ع. 12: 1273–4. DOI:10.1038/sj.cdd.4400774. PMID:11270363.

قراءة متعمقة

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Suzuki Y، Yoshitomo-Nakagawa K، Maruyama K، وآخرون (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. ج. 200 ع. 1–2: 149–56. DOI:10.1016/S0378-1119(97)00411-3. PMID:9373149.
Martinon F، Hofmann K، Tschopp J (2001). "The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation". Curr. Biol. ج. 11 ع. 4: R118–20. DOI:10.1016/S0960-9822(01)00056-2. PMID:11250163.
Wang L، Manji GA، Grenier JM، وآخرون (2002). "PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing". J. Biol. Chem. ج. 277 ع. 33: 29874–80. DOI:10.1074/jbc.M203915200. PMID:12019269.
Grenier JM، Wang L، Manji GA، وآخرون (2002). "Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1". FEBS Lett. ج. 530 ع. 1–3: 73–8. DOI:10.1016/S0014-5793(02)03416-6. PMID:12387869.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
Agostini L، Martinon F، Burns K، وآخرون (2004). "NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder". Immunity. ج. 20 ع. 3: 319–25. DOI:10.1016/S1074-7613(04)00046-9. PMID:15030775.
Bruey JM، Bruey-Sedano N، Newman R، وآخرون (2005). "PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages". J. Biol. Chem. ج. 279 ع. 50: 51897–907. DOI:10.1074/jbc.M406741200. PMID:15456791.
Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
Kinoshita T، Wang Y، Hasegawa M، وآخرون (2005). "PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion". J. Biol. Chem. ج. 280 ع. 23: 21720–5. DOI:10.1074/jbc.M410057200. PMID:15817483.
Rink L، Slupianek A، Stoklosa T، وآخرون (2007). "Enhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cells". Blood. ج. 110 ع. 2: 651–60. DOI:10.1182/blood-2006-08-042630. PMC:1924483. PMID:17431132.

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

[entrez-1] أ ^ب "Entrez Gene: NLRP2 NLR family, pyrin domain containing 2". مؤرشف من الأصل في 2010-12-05.

[pmid12563287-2] Tschopp J، Martinon F، Burns K (فبراير 2003). "NALPs: a novel protein family involved in inflammation". Nat Rev Mol Cell Biol. ج. 4 ع. 2: 95–104. DOI:10.1038/nrm1019. PMID:12563287.

[pmid11270363-3] Bertin J، DiStefano PS (مارس 2001). "The PYRIN domain: a novel motif found in apoptosis and inflammation proteins". Cell Death Differ. ج. 7 ع. 12: 1273–4. DOI:10.1038/sj.cdd.4400774. PMID:11270363.

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