SOCS2

من أرابيكا، الموسوعة الحرة
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An Error has occured retrieving Wikidata item for infobox SOCS2‏ (Suppressor of cytokine signaling 2) هوَ بروتين يُشَفر بواسطة جين SOCS2 في الإنسان.[1][2][3][4][5][1]

الوظيفة

الأهمية السريرية

المراجع

  1. ^ أ ب "Entrez Gene: SOCS2 suppressor of cytokine signaling 2". مؤرشف من الأصل في 2010-12-05.
  2. ^ Dey BR؛ Spence SL؛ Nissley P؛ Furlanetto RW (سبتمبر 1998). "Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor". J. Biol. Chem. ج. 273 ع. 37: 24095–101. DOI:10.1074/jbc.273.37.24095. PMID:9727029.
  3. ^ Minamoto S؛ Ikegame K؛ Ueno K؛ Narazaki M؛ Naka T؛ Yamamoto H؛ Matsumoto T؛ Saito H؛ Hosoe S؛ Kishimoto T (سبتمبر 1997). "Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3". Biochem Biophys Res Commun. ج. 237 ع. 1: 79–83. DOI:10.1006/bbrc.1997.7080. PMID:9266833.
  4. ^ Masuhara M؛ Sakamoto H؛ Matsumoto A؛ Suzuki R؛ Yasukawa H؛ Mitsui K؛ Wakioka T؛ Tanimura S؛ Sasaki A؛ Misawa H؛ Yokouchi M؛ Ohtsubo M؛ Yoshimura A (نوفمبر 1997). "Cloning and characterization of novel CIS family genes". Biochem Biophys Res Commun. ج. 239 ع. 2: 439–46. DOI:10.1006/bbrc.1997.7484. PMID:9344848.
  5. ^ Greenhalgh CJ؛ Bertolino P؛ Asa SL؛ Metcalf D؛ Corbin JE؛ Adams TE؛ Davey HW؛ Nicola NA؛ Hilton DJ؛ Alexander WS (يونيو 2002). "Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)". Mol. Endocrinol. ج. 16 ع. 6: 1394–406. DOI:10.1210/me.16.6.1394. PMID:12040024.

قراءة متعمقة

  • Lopaczynski W (1999). "Differential regulation of signaling pathways for insulin and insulin-like growth factor I.". Acta Biochim. Pol. ج. 46 ع. 1: 51–60. PMID:10453981.
  • Wang J؛ Campbell IL (2002). "Cytokine signaling in the brain: putting a SOCS in it?". J. Neurosci. Res. ج. 67 ع. 4: 423–7. DOI:10.1002/jnr.10145. PMID:11835308.
  • Kile BT، Schulman BA، Alexander WS، وآخرون (2002). "The SOCS box: a tale of destruction and degradation". Trends Biochem. Sci. ج. 27 ع. 5: 235–41. DOI:10.1016/S0968-0004(02)02085-6. PMID:12076535.
  • Pezet A؛ Buteau H؛ Kelly PA؛ Edery M (1997). "The last proline of Box 1 is essential for association with JAK2 and functional activation of the prolactin receptor". Mol. Cell. Endocrinol. ج. 129 ع. 2: 199–208. DOI:10.1016/S0303-7207(97)00063-4. PMID:9202403.
  • Dey BR؛ Spence SL؛ Nissley P؛ Furlanetto RW (1998). "Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor". J. Biol. Chem. ج. 273 ع. 37: 24095–101. DOI:10.1074/jbc.273.37.24095. PMID:9727029.
  • Pezet A؛ Favre H؛ Kelly PA؛ Edery M (1999). "Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling". J. Biol. Chem. ج. 274 ع. 35: 24497–502. DOI:10.1074/jbc.274.35.24497. PMID:10455112.
  • Yandava CN؛ Pillari A؛ Drazen JM (1999). "Radiation hybrid and cytogenetic mapping of SOCS1 and SOCS2 to chromosomes 16p13 and 12q, respectively". Genomics. ج. 61 ع. 1: 108–11. DOI:10.1006/geno.1999.5937. PMID:10512686.
  • Ram PA؛ Waxman DJ (2000). "SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms". J. Biol. Chem. ج. 274 ع. 50: 35553–61. DOI:10.1074/jbc.274.50.35553. PMID:10585430.
  • Metcalf D، Greenhalgh CJ، Viney E، وآخرون (2000). "Gigantism in mice lacking suppressor of cytokine signalling-2". Nature. ج. 405 ع. 6790: 1069–73. DOI:10.1038/35016611. PMID:10890450.
  • Shen X؛ Hong F؛ Nguyen VA؛ Gao B (2000). "IL-10 attenuates IFN-alpha-activated STAT1 in the liver: involvement of SOCS2 and SOCS3". FEBS Lett. ج. 480 ع. 2–3: 132–6. DOI:10.1016/S0014-5793(00)01905-0. PMID:11034314.
  • Eyckerman S، Verhee A، der Heyden JV، وآخرون (2002). "Design and application of a cytokine-receptor-based interaction trap". Nat. Cell Biol. ج. 3 ع. 12: 1114–9. DOI:10.1038/ncb1201-1114. PMID:11781573.
  • Schultheis B، Carapeti-Marootian M، Hochhaus A، وآخرون (2002). "Overexpression of SOCS-2 in advanced stages of chronic myeloid leukemia: possible inadequacy of a negative feedback mechanism". Blood. ج. 99 ع. 5: 1766–75. DOI:10.1182/blood.V99.5.1766. PMID:11861294.
  • Blumenstein M؛ Bowen-Shauver JM؛ Keelan JA؛ Mitchell MD (2002). "Identification of suppressors of cytokine signaling (SOCS) proteins in human gestational tissues: differential regulation is associated with the onset of labor". J. Clin. Endocrinol. Metab. ج. 87 ع. 3: 1094–7. DOI:10.1210/jc.87.3.1094. PMID:11889171.
  • Biener E، Maurice S، Sandowski Y، وآخرون (2003). "Recombinant human CIS2 (SOCS2) protein: subcloning, expression, purification, and characterization". Protein Expr. Purif. ج. 25 ع. 2: 305–12. DOI:10.1016/S1046-5928(02)00013-X. PMID:12135564.
  • Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
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