ITIH3

An Error has occured retrieving Wikidata item for infobox ITIH3‏ (Inter-alpha-trypsin inhibitor heavy chain 3) هوَ بروتين يُشَفر بواسطة جين ITIH3 في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ Jean L، Risler JL، Nagase T، Coulouarn C، Nomura N، Salier JP (مايو 1999). "The nuclear protein PH5P of the inter-alpha-inhibitor superfamily: a missing link between poly(ADP-ribose)polymerase and the inter-alpha-inhibitor family and a novel actor of DNA repair?". FEBS Lett. ج. 446 ع. 1: 6–8. DOI:10.1016/S0014-5793(99)00173-8. PMID:10100603.
^ "Entrez Gene: ITIH3 inter-alpha (globulin) inhibitor H3". مؤرشف من الأصل في 2010-12-05.
^ Diarra-Mehrpour M، Bourguignon J، Sesboue R، Mattei MG، Passage E، Salier JP، Martin JP (أبريل 1989). "Human plasma inter-alpha-trypsin inhibitor is encoded by four genes on three chromosomes". Eur J Biochem. ج. 179 ع. 1: 147–54. DOI:10.1111/j.1432-1033.1989.tb14532.x. PMID:2465147.

قراءة متعمقة

Salier JP، Simon D، Rouet P، وآخرون (1992). "Homologous chromosomal locations of the four genes for inter-alpha-inhibitor and pre-alpha-inhibitor family in human and mouse: assignment of the ancestral gene for the lipocalin superfamily". Genomics. ج. 14 ع. 1: 83–8. DOI:10.1016/S0888-7543(05)80287-3. PMID:1385302.
Enghild JJ، Salvesen G، Hefta SA، وآخرون (1991). "Chondroitin 4-sulfate covalently cross-links the chains of the human blood protein pre-alpha-inhibitor". J. Biol. Chem. ج. 266 ع. 2: 747–51. PMID:1898736.
Salier JP، Diarra-Mehrpour M، Sesboue R، وآخرون (1988). "Isolation and characterization of cDNAs encoding the heavy chain of human inter-alpha-trypsin inhibitor (I alpha TI): unambiguous evidence for multipolypeptide chain structure of I alpha TI". Proc. Natl. Acad. Sci. U.S.A. ج. 84 ع. 23: 8272–6. DOI:10.1073/pnas.84.23.8272. PMC:299524. PMID:2446322.
Enghild JJ، Thøgersen IB، Pizzo SV، Salvesen G (1989). "Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan". J. Biol. Chem. ج. 264 ع. 27: 15975–81. PMID:2476436.
Diarra-Mehrpour M، Bourguignon J، Sarafan N، وآخرون (1994). "Tandem orientation of the inter-alpha-trypsin inhibitor heavy chain H1 and H3 genes". Biochim. Biophys. Acta. ج. 1219 ع. 2: 551–4. DOI:10.1016/0167-4781(94)90087-6. PMID:7522574.
Bourguignon J، Diarra-Mehrpour M، Thiberville L، وآخرون (1993). "Human pre-alpha-trypsin inhibitor-precursor heavy chain. cDNA and deduced amino-acid sequence". Eur. J. Biochem. ج. 212 ع. 3: 771–6. DOI:10.1111/j.1432-1033.1993.tb17717.x. PMID:7681778.
Maruyama K، Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. ج. 138 ع. 1–2: 171–4. DOI:10.1016/0378-1119(94)90802-8. PMID:8125298.
Blom AM، Thuveson M، Fries E (1998). "Intracellular coupling of bikunin and the heavy chain of rat pre-alpha-inhibitor in COS-1 cells". Biochem. J. ج. 328 ع. 1: 185–91. PMC:1218904. PMID:9359851.
Suzuki Y، Yoshitomo-Nakagawa K، Maruyama K، وآخرون (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. ج. 200 ع. 1–2: 149–56. DOI:10.1016/S0378-1119(97)00411-3. PMID:9373149.
Diarra-Mehrpour M، Sarafan N، Bourguignon J، وآخرون (1998). "Human inter-alpha-trypsin inhibitor heavy chain H3 gene. Genomic organization, promoter analysis, and gene linkage". J. Biol. Chem. ج. 273 ع. 41: 26809–19. DOI:10.1074/jbc.273.41.26809. PMID:9756925.
Thuveson M، Fries E (1999). "Intracellular proteolytic processing of the heavy chain of rat pre-alpha-inhibitor. The COOH-terminal propeptide is required for coupling to bikunin". J. Biol. Chem. ج. 274 ع. 10: 6741–6. DOI:10.1074/jbc.274.10.6741. PMID:10037773.
Bourguignon J، Borghi H، Sesboüé R، وآخرون (1999). "Immunohistochemical distribution of inter-alpha-trypsin inhibitor chains in normal and malignant human lung tissue". J. Histochem. Cytochem. ج. 47 ع. 12: 1625–32. DOI:10.1177/002215549904701214. PMID:10567446.
Thuveson M، Fries E (2000). "The low pH in trans-Golgi triggers autocatalytic cleavage of pre-alpha -inhibitor heavy chain precursor". J. Biol. Chem. ج. 275 ع. 40: 30996–1000. DOI:10.1074/jbc.M002399200. PMID:10893227.
Kato M، Seki N، Sugano S، وآخرون (2002). "Identification of sonic hedgehog-responsive genes using cDNA microarray". Biochem. Biophys. Res. Commun. ج. 289 ع. 2: 472–8. DOI:10.1006/bbrc.2001.5976. PMID:11716497.
Paris S، Sesboüé R، Delpech B، وآخرون (2002). "Inhibition of tumor growth and metastatic spreading by overexpression of inter-alpha-trypsin inhibitor family chains". Int. J. Cancer. ج. 97 ع. 5: 615–20. DOI:10.1002/ijc.10120. PMID:11807786.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.

هذه بذرة مقالة عن جين على كروموسوم 3 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[pmid10100603-1] Jean L، Risler JL، Nagase T، Coulouarn C، Nomura N، Salier JP (مايو 1999). "The nuclear protein PH5P of the inter-alpha-inhibitor superfamily: a missing link between poly(ADP-ribose)polymerase and the inter-alpha-inhibitor family and a novel actor of DNA repair?". FEBS Lett. ج. 446 ع. 1: 6–8. DOI:10.1016/S0014-5793(99)00173-8. PMID:10100603.

[entrez-2] "Entrez Gene: ITIH3 inter-alpha (globulin) inhibitor H3". مؤرشف من الأصل في 2010-12-05.

[pmid2465147-3] Diarra-Mehrpour M، Bourguignon J، Sesboue R، Mattei MG، Passage E، Salier JP، Martin JP (أبريل 1989). "Human plasma inter-alpha-trypsin inhibitor is encoded by four genes on three chromosomes". Eur J Biochem. ج. 179 ع. 1: 147–54. DOI:10.1111/j.1432-1033.1989.tb14532.x. PMID:2465147.

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