TXNIP
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هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
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An Error has occured retrieving Wikidata item for infobox TXNIP (Thioredoxin interacting protein) هوَ بروتين يُشَفر بواسطة جين TXNIP في الإنسان.[1][2]
الوظيفة

الأهمية السريرية

المراجع
- ^ Chen KS, DeLuca HF (Sep 1994). "Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3". Biochimica et Biophysica Acta. 1219 (1): 26–32. doi:10.1016/0167-4781(94)90242-9. PMID 8086474. الوسيط
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تم تجاهله (مساعدة) - ^ "Entrez Gene: TXNIP thioredoxin interacting protein". مؤرشف من الأصل في 05 ديسمبر 2010. الوسيط
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تم تجاهله (مساعدة)
قراءة متعمقة
- Nishiyama A, Matsui M, Iwata S, Hirota K, Masutani H, Nakamura H, Takagi Y, Sono H, Gon Y, Yodoi J (Jul 1999). "Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression". The Journal of Biological Chemistry. 274 (31): 21645–50. doi:10.1074/jbc.274.31.21645. PMID 10419473. الوسيط
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تم تجاهله (مساعدة) - Ludwig DL, Kotanides H, Le T, Chavkin D, Bohlen P, Witte L (May 2001). "Cloning, genetic characterization, and chromosomal mapping of the mouse VDUP1 gene". Gene. 269 (1–2): 103–12. doi:10.1016/S0378-1119(01)00455-3. PMID 11376942. الوسيط
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تم تجاهله (مساعدة) - Bodnar JS, Chatterjee A, Castellani LW, Ross DA, Ohmen J, Cavalcoli J, Wu C, Dains KM, Catanese J, Chu M, Sheth SS, Charugundla K, Demant P, West DB, de Jong P, Lusis AJ (Jan 2002). "Positional cloning of the combined hyperlipidemia gene Hyplip1". Nature Genetics. 30 (1): 110–6. doi:10.1038/ng811. PMC 2846781. PMID 11753387. الوسيط
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تم تجاهله (مساعدة) - Joguchi A, Otsuka I, Minagawa S, Suzuki T, Fujii M, Ayusawa D (Apr 2002). "Overexpression of VDUP1 mRNA sensitizes HeLa cells to paraquat". Biochemical and Biophysical Research Communications. 293 (1): 293–7. doi:10.1016/S0006-291X(02)00208-5. PMID 12054598. الوسيط
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تم تجاهله (مساعدة) - Butler LM, Zhou X, Xu WS, Scher HI, Rifkind RA, Marks PA, Richon VM (Sep 2002). "The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin". Proceedings of the National Academy of Sciences of the United States of America. 99 (18): 11700–5. doi:10.1073/pnas.182372299. PMC 129332. PMID 12189205. الوسيط
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تم تجاهله (مساعدة) - Schulze PC, De Keulenaer GW, Yoshioka J, Kassik KA, Lee RT (Oct 2002). "Vitamin D3-upregulated protein-1 (VDUP-1) regulates redox-dependent vascular smooth muscle cell proliferation through interaction with thioredoxin". Circulation Research. 91 (8): 689–95. doi:10.1161/01.RES.0000037982.55074.F6. PMID 12386145. الوسيط
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تم تجاهله (مساعدة) - Han SH, Jeon JH, Ju HR, Jung U, Kim KY, Yoo HS, Lee YH, Song KS, Hwang HM, Na YS, Yang Y, Lee KN, Choi I (Jun 2003). "VDUP1 upregulated by TGF-beta1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression". Oncogene. 22 (26): 4035–46. doi:10.1038/sj.onc.1206610. PMID 12821938. الوسيط
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تم تجاهله (مساعدة) - Champliaud MF, Viel A, Baden HP (Oct 2003). "The expression of vitamin D-upregulated protein 1 in skin and its interaction with sciellin in cultured keratinocytes". The Journal of Investigative Dermatology. 121 (4): 781–5. doi:10.1046/j.1523-1747.2003.12539.x. PMID 14632196. الوسيط
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تم تجاهله (مساعدة) - Kim KY, Shin SM, Kim JK, Paik SG, Yang Y, Choi I (Mar 2004). "Heat shock factor regulates VDUP1 gene expression". Biochemical and Biophysical Research Communications. 315 (2): 369–75. doi:10.1016/j.bbrc.2004.01.047. PMID 14766217. الوسيط
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تم تجاهله (مساعدة) - Schulze PC, Yoshioka J, Takahashi T, He Z, King GL, Lee RT (Jul 2004). "Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein". The Journal of Biological Chemistry. 279 (29): 30369–74. doi:10.1074/jbc.M400549200. PMID 15128745. الوسيط
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تم تجاهله (مساعدة) - Coon H, Singh N, Dunn D, Eckfeldt JH, Province MA, Hopkins PN, Weiss R, Hunt SC, Leppert MF (Jun 2004). "TXNIP gene not associated with familial combined hyperlipidemia in the NHLBI Family Heart Study". Atherosclerosis. 174 (2): 357–62. doi:10.1016/j.atherosclerosis.2004.02.004. PMID 15136067. الوسيط
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تم تجاهله (مساعدة) - Nishinaka Y, Masutani H, Oka S, Matsuo Y, Yamaguchi Y, Nishio K, Ishii Y, Yodoi J (Sep 2004). "Importin alpha1 (Rch1) mediates nuclear translocation of thioredoxin-binding protein-2/vitamin D(3)-up-regulated protein 1". The Journal of Biological Chemistry. 279 (36): 37559–65. doi:10.1074/jbc.M405473200. PMID 15234975. الوسيط
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تم تجاهله (مساعدة) - Aitken CJ, Hodge JM, Nishinaka Y, Vaughan T, Yodoi J, Day CJ, Morrison NA, Nicholson GC (Dec 2004). "Regulation of human osteoclast differentiation by thioredoxin binding protein-2 and redox-sensitive signaling". Journal of Bone and Mineral Research. 19 (12): 2057–64. doi:10.1359/JBMR.040913. PMID 15537450. الوسيط
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تم تجاهله (مساعدة) - Yamawaki H, Pan S, Lee RT, Berk BC (Mar 2005). "Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells". The Journal of Clinical Investigation. 115 (3): 733–8. doi:10.1172/JCI23001. PMC 546457. PMID 15696199. الوسيط
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تم تجاهله (مساعدة) - Minn AH, Hafele C, Shalev A (May 2005). "Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis". Endocrinology. 146 (5): 2397–405. doi:10.1210/en.2004-1378. PMID 15705778. الوسيط
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تم تجاهله (مساعدة)
