TLE2

An Error has occured retrieving Wikidata item for infobox TLE2‏ (Transducin like enhancer of split 2) هوَ بروتين يُشَفر بواسطة جين TLE2 في الإنسان.

الوظيفة

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الأهمية السريرية

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قراءة متعمقة

• "Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins". Nat. Genet. 2 (2): 119–27. 1993. doi:10.1038/ng1092-119. PMID 1303260.
• "Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein". Eur. J. Biochem. 216 (1): 343–52. 1993. doi:10.1111/j.1432-1033.1993.tb18151.x. PMID 8365415.
• "The Groucho/transducin-like enhancer of split transcriptional repressors interact with the genetically defined amino-terminal silencing domain of histone H3". J. Biol. Chem. 272 (42): 26604–10. 1997. doi:10.1074/jbc.272.42.26604. PMID 9334241.
• "Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms". Biochem. J. 337 (1): 13–7. 1999. doi:10.1042/0264-6021:3370013. PMC 1219929. PMID 9854018.
• "Transducin-like Enhancer of split 2, a mammalian homologue of Drosophila Groucho, acts as a transcriptional repressor, interacts with Hairy/Enhancer of split proteins, and is expressed during neuronal development". Eur. J. Biochem. 258 (2): 339–49. 1999. doi:10.1046/j.1432-1327.1998.2580339.x. PMID 9874198.
• "PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins". Genes Dev. 13 (1): 125–37. 1999. doi:10.1101/gad.13.1.125. PMC 316372. PMID 9887105.
• "Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription". J. Cell Sci. 113 (12): 2221–31. 2000. PMID 10825294.
• "All Tcf HMG box transcription factors interact with Groucho-related co-repressors". Nucleic Acids Res. 29 (7): 1410–9. 2001. doi:10.1093/nar/29.7.1410. PMC 31284. PMID 11266540.
• "HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences". J. Biol. Chem. 277 (9): 7021–8. 2002. doi:10.1074/jbc.M108417200. PMID 11748221.
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
• "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. 2004. Bibcode:2004Natur.428..529G. doi:10.1038/nature02399. PMID 15057824.
• "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. 2005. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514.
• "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation". Nat. Cell Biol. 8 (11): 1277–83. 2006. doi:10.1038/ncb1490. PMID 17041588.

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