QKI

An Error has occured retrieving Wikidata item for infobox QKI‏ (QKI, KH domain containing RNA binding) هوَ بروتين يُشَفر بواسطة جين QKI في الإنسان.^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]

الوظيفة

الأهمية السريرية

المراجع

^ "Entrez Gene: QKI quaking homolog, KH domain RNA binding (mouse)". مؤرشف من الأصل في 2010-12-05.
^ Wang L، Xu J، Zeng L، Ye X، Wu Q، Dai J، Ji C، Gu S، Zhao C، Xie Y، Mao Y (ديسمبر 2002). "Cloning and characterization of a novel human STAR domain containing cDNA KHDRBS2". Mol. Biol. Rep. ج. 29 ع. 4: 369–75. DOI:10.1023/A:1021246109101. PMID:12549823.
^ Vernet C، Artzt K (ديسمبر 1997). "STAR, a gene family involved in signal transduction and activation of RNA". Trends Genet. ج. 13 ع. 12: 479–84. DOI:10.1016/S0168-9525(97)01269-9. PMID:9433137.
^ Venables JP، Vernet C، Chew SL، Elliott DJ، Cowmeadow RB، Wu J، Cooke HJ، Artzt K، Eperon IC (يونيو 1999). "T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis". Hum. Mol. Genet. ج. 8 ع. 6: 959–69. DOI:10.1093/hmg/8.6.959. PMID:10332027.
^ Haroutunian V، Katsel P، Dracheva S، Davis KL (أكتوبر 2006). "The human homolog of the QKI gene affected in the severe dysmyelination "quaking" mouse phenotype: downregulated in multiple brain regions in schizophrenia". Am J Psychiatry. ج. 163 ع. 10: 1834–7. DOI:10.1176/ajp.2006.163.10.1834. PMID:17012699.
^ Saccomanno L، Loushin C، Jan E، Punkay E، Artzt K، Goodwin EB (أكتوبر 1999). "The STAR protein QKI-6 is a translational repressor". Proc. Natl. Acad. Sci. U.S.A. ج. 96 ع. 22: 12605–10. Bibcode:1999PNAS...9612605S. DOI:10.1073/pnas.96.22.12605. PMC:23011. PMID:10535969.
^ Aberg K، Saetre P، Jareborg N، Jazin E (مايو 2006). "Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia". Proc. Natl. Acad. Sci. U.S.A. ج. 103 ع. 19: 7482–7. Bibcode:2006PNAS..103.7482A. DOI:10.1073/pnas.0601213103. PMC:1464365. PMID:16641098.
^ Chen T، Richard S (أغسطس 1998). "Structure-function analysis of Qk1: a lethal point mutation in mouse quaking prevents homodimerization". Mol. Cell. Biol. ج. 18 ع. 8: 4863–71. PMC:109071. PMID:9671495. مؤرشف من الأصل في 2019-12-07.

قراءة متعمقة

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Saccomanno L، Loushin C، Jan E، وآخرون (1999). "The STAR protein QKI-6 is a translational repressor". Proc. Natl. Acad. Sci. U.S.A. ج. 96 ع. 22: 12605–10. Bibcode:1999PNAS...9612605S. DOI:10.1073/pnas.96.22.12605. PMC:23011. PMID:10535969.
Li ZZ، Kondo T، Murata T، وآخرون (2002). "Expression of Hqk encoding a KH RNA binding protein is altered in human glioma". Jpn. J. Cancer Res. ج. 93 ع. 2: 167–77. DOI:10.1111/j.1349-7006.2002.tb01255.x. PMID:11856480.
Wu JI، Reed RB، Grabowski PJ، Artzt K (2002). "Function of quaking in myelination: regulation of alternative splicing". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 7: 4233–8. Bibcode:2002PNAS...99.4233W. DOI:10.1073/pnas.072090399. PMC:123631. PMID:11917126.
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Côté J، Boisvert FM، Boulanger MC، وآخرون (2003). "Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1". Mol. Biol. Cell. ج. 14 ع. 1: 274–87. DOI:10.1091/mbc.E02-08-0484. PMC:140244. PMID:12529443.
Mungall AJ، Palmer SA، Sims SK، وآخرون (2003). "The DNA sequence and analysis of human chromosome 6". Nature. ج. 425 ع. 6960: 805–11. DOI:10.1038/nature02055. PMID:14574404.
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Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
Rual JF، Venkatesan K، Hao T، وآخرون (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. ج. 437 ع. 7062: 1173–8. Bibcode:2005Natur.437.1173R. DOI:10.1038/nature04209. PMID:16189514.
Ichimura K، Mungall AJ، Fiegler H، وآخرون (2006). "Small regions of overlapping deletions on 6q26 in human astrocytic tumours identified using chromosome 6 tile path array-CGH". Oncogene. ج. 25 ع. 8: 1261–71. DOI:10.1038/sj.onc.1209156. PMC:2760128. PMID:16205629.
Aberg K، Saetre P، Lindholm E، وآخرون (2006). "Human QKI, a new candidate gene for schizophrenia involved in myelination". Am. J. Med. Genet. B Neuropsychiatr. Genet. ج. 141 ع. 1: 84–90. DOI:10.1002/ajmg.b.30243. PMID:16342280.
Aberg K، Saetre P، Jareborg N، Jazin E (2006). "Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia". Proc. Natl. Acad. Sci. U.S.A. ج. 103 ع. 19: 7482–7. Bibcode:2006PNAS..103.7482A. DOI:10.1073/pnas.0601213103. PMC:1464365. PMID:16641098.
Lim J، Hao T، Shaw C، وآخرون (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. ج. 125 ع. 4: 801–14. DOI:10.1016/j.cell.2006.03.032. PMID:16713569.
Haroutunian V، Katsel P، Dracheva S، Davis KL (2006). "The human homolog of the QKI gene affected in the severe dysmyelination "quaking" mouse phenotype: downregulated in multiple brain regions in schizophrenia". The American Journal of Psychiatry. ج. 163 ع. 10: 1834–7. DOI:10.1176/ajp.2006.163.10.1834. PMID:17012699.
Zhao L، Tian D، Xia M، وآخرون (2006). "Rescuing qkV dysmyelination by a single isoform of the selective RNA-binding protein QKI". J. Neurosci. ج. 26 ع. 44: 11278–86. DOI:10.1523/JNEUROSCI.2677-06.2006. PMID:17079655.

هذه بذرة مقالة عن جين على كروموسوم 6 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[entrez-1] "Entrez Gene: QKI quaking homolog, KH domain RNA binding (mouse)". مؤرشف من الأصل في 2010-12-05.

[pmid12549823-2] Wang L، Xu J، Zeng L، Ye X، Wu Q، Dai J، Ji C، Gu S، Zhao C، Xie Y، Mao Y (ديسمبر 2002). "Cloning and characterization of a novel human STAR domain containing cDNA KHDRBS2". Mol. Biol. Rep. ج. 29 ع. 4: 369–75. DOI:10.1023/A:1021246109101. PMID:12549823.

[pmid9433137-3] Vernet C، Artzt K (ديسمبر 1997). "STAR, a gene family involved in signal transduction and activation of RNA". Trends Genet. ج. 13 ع. 12: 479–84. DOI:10.1016/S0168-9525(97)01269-9. PMID:9433137.

[pmid10332027-4] Venables JP، Vernet C، Chew SL، Elliott DJ، Cowmeadow RB، Wu J، Cooke HJ، Artzt K، Eperon IC (يونيو 1999). "T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis". Hum. Mol. Genet. ج. 8 ع. 6: 959–69. DOI:10.1093/hmg/8.6.959. PMID:10332027.

[5] Haroutunian V، Katsel P، Dracheva S، Davis KL (أكتوبر 2006). "The human homolog of the QKI gene affected in the severe dysmyelination "quaking" mouse phenotype: downregulated in multiple brain regions in schizophrenia". Am J Psychiatry. ج. 163 ع. 10: 1834–7. DOI:10.1176/ajp.2006.163.10.1834. PMID:17012699.

[pmid10535969-6] Saccomanno L، Loushin C، Jan E، Punkay E، Artzt K، Goodwin EB (أكتوبر 1999). "The STAR protein QKI-6 is a translational repressor". Proc. Natl. Acad. Sci. U.S.A. ج. 96 ع. 22: 12605–10. Bibcode:1999PNAS...9612605S. DOI:10.1073/pnas.96.22.12605. PMC:23011. PMID:10535969.

[7] Aberg K، Saetre P، Jareborg N، Jazin E (مايو 2006). "Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia". Proc. Natl. Acad. Sci. U.S.A. ج. 103 ع. 19: 7482–7. Bibcode:2006PNAS..103.7482A. DOI:10.1073/pnas.0601213103. PMC:1464365. PMID:16641098.

[pmid9671495-8] Chen T، Richard S (أغسطس 1998). "Structure-function analysis of Qk1: a lethal point mutation in mouse quaking prevents homodimerization". Mol. Cell. Biol. ج. 18 ع. 8: 4863–71. PMC:109071. PMID:9671495. مؤرشف من الأصل في 2019-12-07.

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