PPARGC1B
من أرابيكا، الموسوعة العربية الحرة
المزيد من اللغات
المزيد من الإجراءات
An Error has occured retrieving Wikidata item for infobox PPARGC1B (PPARG coactivator 1 beta) هوَ بروتين يُشَفر بواسطة جين PPARGC1B في الإنسان.[1][2][3]
الوظيفة
![[أيقونة]](/%D9%85%D9%84%D9%81:Crystal_xedit.svg){kind=small} | هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
| هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
- ^ Kressler D، Schreiber SN، Knutti D، Kralli A (أبريل 2002). "The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha". J Biol Chem. ج. 277 ع. 16: 13918–25. DOI:10.1074/jbc.M201134200. PMID:11854298.
- ^ Ek J، Andersen G، Urhammer SA، Gaede PH، Drivsholm T، Borch-Johnsen K، Hansen T، Pedersen O (يناير 2002). "Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus". Diabetologia. ج. 44 ع. 12: 2220–6. DOI:10.1007/s001250100032. PMID:11793024.
- ^ "Entrez Gene: PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Handschin C، Spiegelman BM (2007). "Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism". Endocr. Rev. ج. 27 ع. 7: 728–35. DOI:10.1210/er.2006-0037. PMID:17018837.
- Esterbauer H، Oberkofler H، Krempler F، Patsch W (2000). "Human peroxisome proliferator activated receptor gamma coactivator 1 (PPARGC1) gene: cDNA sequence, genomic organization, chromosomal localization, and tissue expression". Genomics. ج. 62 ع. 1: 98–102. DOI:10.1006/geno.1999.5977. PMID:10585775.
- Knutti D، Kaul A، Kralli A (2000). "A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen". Mol. Cell. Biol. ج. 20 ع. 7: 2411–22. DOI:10.1128/MCB.20.7.2411-2422.2000. PMC:85422. PMID:10713165.
- Lin J، Puigserver P، Donovan J، وآخرون (2002). "Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor". J. Biol. Chem. ج. 277 ع. 3: 1645–8. DOI:10.1074/jbc.C100631200. PMID:11733490.
- Lacquemant C، Chikri M، Boutin P، وآخرون (2002). "No association between the G482S polymorphism of the proliferator-activated receptor-gamma coactivator-1 (PGC-1) gene and Type II diabetes in French Caucasians". Diabetologia. ج. 45 ع. 4: 602–3, author reply 604. DOI:10.1007/s00125-002-0783-z. PMID:12032643.
- Hara K، Tobe K، Okada T، وآخرون (2003). "A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes". Diabetologia. ج. 45 ع. 5: 740–3. DOI:10.1007/s00125-002-0803-z. PMID:12107756.
- Huss JM، Kopp RP، Kelly DP (2002). "Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha". J. Biol. Chem. ج. 277 ع. 43: 40265–74. DOI:10.1074/jbc.M206324200. PMID:12181319.
- Hentschke M، Süsens U، Borgmeyer U (2003). "PGC-1 and PERC, coactivators of the estrogen receptor-related receptor gamma". Biochem. Biophys. Res. Commun. ج. 299 ع. 5: 872–9. DOI:10.1016/S0006-291X(02)02753-5. PMID:12470660.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Shiraki T، Sakai N، Kanaya E، Jingami H (2003). "Activation of orphan nuclear constitutive androstane receptor requires subnuclear targeting by peroxisome proliferator-activated receptor gamma coactivator-1 alpha. A possible link between xenobiotic response and nutritional state". J. Biol. Chem. ج. 278 ع. 13: 11344–50. DOI:10.1074/jbc.M212859200. PMID:12551939.
- Hammarstedt A، Jansson PA، Wesslau C، وآخرون (2003). "Reduced expression of PGC-1 and insulin-signaling molecules in adipose tissue is associated with insulin resistance". Biochem. Biophys. Res. Commun. ج. 301 ع. 2: 578–82. DOI:10.1016/S0006-291X(03)00014-7. PMID:12565902.
- Meirhaeghe A، Crowley V، Lenaghan C، وآخرون (2003). "Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo". Biochem. J. ج. 373 ع. Pt 1: 155–65. DOI:10.1042/BJ20030200. PMC:1223480. PMID:12678921.
- Patti ME، Butte AJ، Crunkhorn S، وآخرون (2003). "Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1". Proc. Natl. Acad. Sci. U.S.A. ج. 100 ع. 14: 8466–71. DOI:10.1073/pnas.1032913100. PMC:166252. PMID:12832613.
- Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
- Ling C، Poulsen P، Carlsson E، وآخرون (2004). "Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins". J. Clin. Invest. ج. 114 ع. 10: 1518–26. DOI:10.1172/JCI21889. PMC:525741. PMID:15546003.
- Andersen G، Wegner L، Yanagisawa K، وآخرون (2006). "Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity". J. Med. Genet. ج. 42 ع. 5: 402–7. DOI:10.1136/jmg.2004.026278. PMC:1736055. PMID:15863669.
- Staiger H، Staiger K، Haas C، وآخرون (2005). "Fatty acid-induced differential regulation of the genes encoding peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in human skeletal muscle cells that have been differentiated in vitro". Diabetologia. ج. 48 ع. 10: 2115–8. DOI:10.1007/s00125-005-1895-z. PMID:16132959.
- Wirtenberger M، Tchatchou S، Hemminki K، وآخرون (2006). "Associations of genetic variants in the estrogen receptor coactivators PPARGC1A, PPARGC1B and EP300 with familial breast cancer". Carcinogenesis. ج. 27 ع. 11: 2201–8. DOI:10.1093/carcin/bgl067. PMID:16704985.
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