UBE2N

An Error has occured retrieving Wikidata item for infobox UBE2N‏ (Ubiquitin conjugating enzyme E2 N) هوَ بروتين يُشَفر بواسطة جين UBE2N في الإنسان.

الوظيفة

هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.

الأهمية السريرية

هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.

قراءة متعمقة

• "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. 1997. doi:10.1101/gr.6.9.791. PMID 8889548.
• "Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair". Cell. 96 (5): 645–53. 1999. doi:10.1016/S0092-8674(00)80575-9. PMID 10089880.
• "Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain". Cell. 103 (2): 351–61. 2000. doi:10.1016/S0092-8674(00)00126-4. PMID 11057907.
• "Defining polyubiquitin chain topology". Nat. Struct. Biol. 8 (8): 650–2. 2001. doi:10.1038/90337. PMID 11473244.
• "Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13". Nat. Struct. Biol. 8 (8): 669–73. 2001. doi:10.1038/90373. PMID 11473255.
• "Roles of mouse UBC13 in DNA postreplication repair and Lys63-linked ubiquitination". Gene. 285 (1–2): 183–91. 2002. doi:10.1016/S0378-1119(02)00409-2. PMID 12039045.
• "An NMR-based model of the ubiquitin-bound human ubiquitin conjugation complex Mms2.Ubc13. The structural basis for lysine 63 chain catalysis". J. Biol. Chem. 278 (15): 13151–8. 2003. doi:10.1074/jbc.M212353200. PMID 12569095.
• "GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells". Immunity. 18 (4): 535–47. 2003. doi:10.1016/S1074-7613(03)00084-0. PMID 12705856.
• "Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human". Nat. Genet. 34 (4): 403–12. 2003. doi:10.1038/ng1220. PMID 12881723.
• "The Chfr mitotic checkpoint protein functions with Ubc13-Mms2 to form Lys63-linked polyubiquitin chains". Oncogene. 22 (46): 7101–7. 2003. doi:10.1038/sj.onc.1206831. PMID 14562038.
• "Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO". Nature. 427 (6970): 167–71. 2004. doi:10.1038/nature02273. PMID 14695475.
• "The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes". Mol. Cell. 14 (3): 289–301. 2004. doi:10.1016/S1097-2765(04)00236-9. PMID 15125833.
• "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. 2004. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
• "A single Mms2 "key" residue insertion into a Ubc13 pocket determines the interface specificity of a human Lys63 ubiquitin conjugation complex". J. Biol. Chem. 280 (18): 17891–900. 2005. doi:10.1074/jbc.M410469200. PMID 15749714.
• "ISG15 modification of Ubc13 suppresses its ubiquitin-conjugating activity". Biochem. Biophys. Res. Commun. 336 (1): 9–13. 2005. doi:10.1016/j.bbrc.2005.08.034. PMID 16112642.
• "ISG15 modification of ubiquitin E2 Ubc13 disrupts its ability to form thioester bond with ubiquitin". Biochem. Biophys. Res. Commun. 336 (1): 61–8. 2005. doi:10.1016/j.bbrc.2005.08.038. PMID 16122702.

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