RRAS2

An Error has occured retrieving Wikidata item for infobox RRAS2‏ (RAS related 2) هوَ بروتين يُشَفر بواسطة جين RRAS2 في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ "Entrez Gene: RRAS2 related RAS viral (r-ras) oncogene homolog 2". مؤرشف من الأصل في 2010-12-05.
^ Drivas GT، Shih A، Coutavas E، Rush MG، D'Eustachio P (مايو 1990). "Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line". Mol Cell Biol. ج. 10 ع. 4: 1793–8. PMC:362288. PMID:2108320.
^ Chan AM، Miki T، Meyers KA، Aaronson SA (سبتمبر 1994). "A human oncogene of the RAS superfamily unmasked by expression cDNA cloning". Proc Natl Acad Sci U S A. ج. 91 ع. 16: 7558–62. Bibcode:1994PNAS...91.7558C. DOI:10.1073/pnas.91.16.7558. PMC:44441. PMID:8052619.

قراءة متعمقة

Ehrhardt A، Ehrhardt GR، Guo X، Schrader JW (2002). "Ras and relatives--job sharing and networking keep an old family together". Exp. Hematol. ج. 30 ع. 10: 1089–106. DOI:10.1016/S0301-472X(02)00904-9. PMID:12384139.
Rosário M، Paterson HF، Marshall CJ (1999). "Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells". EMBO J. ج. 18 ع. 5: 1270–9. DOI:10.1093/emboj/18.5.1270. PMC:1171217. PMID:10064593.
Linnemann T، Geyer M، Jaitner BK، وآخرون (1999). "Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily". J. Biol. Chem. ج. 274 ع. 19: 13556–62. DOI:10.1074/jbc.274.19.13556. PMID:10224125.
Ehrhardt GR، Leslie KB، Lee F، وآخرون (1999). "M-Ras, a widely expressed 29-kD homologue of p21 Ras: expression of a constitutively active mutant results in factor-independent growth of an interleukin-3-dependent cell line". Blood. ج. 94 ع. 7: 2433–44. PMID:10498616.
Movilla N، Crespo P، Bustelo XR (1999). "Signal transduction elements of TC21, an oncogenic member of the R-Ras subfamily of GTP-binding proteins". Oncogene. ج. 18 ع. 43: 5860–9. DOI:10.1038/sj.onc.1202968. PMID:10557073.
Ohba Y، Mochizuki N، Yamashita S، وآخرون (2000). "Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3". J. Biol. Chem. ج. 275 ع. 26: 20020–6. DOI:10.1074/jbc.M000981200. PMID:10777492.
Figueroa C، Taylor J، Vojtek AB (2001). "Prenylated Rab acceptor protein is a receptor for prenylated small GTPases". J. Biol. Chem. ج. 276 ع. 30: 28219–25. DOI:10.1074/jbc.M101763200. PMID:11335720.
Murphy GA، Graham SM، Morita S، وآخرون (2002). "Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformation". J. Biol. Chem. ج. 277 ع. 12: 9966–75. DOI:10.1074/jbc.M109059200. PMID:11788587.
Rong R، He Q، Liu Y، وآخرون (2002). "TC21 mediates transformation and cell survival via activation of phosphatidylinositol 3-kinase/Akt and NF-kappaB signaling pathway". Oncogene. ج. 21 ع. 7: 1062–70. DOI:10.1038/sj.onc.1205154. PMID:11850823.
Ortiz-Vega S، Khokhlatchev A، Nedwidek M، وآخرون (2002). "The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1". Oncogene. ج. 21 ع. 9: 1381–90. DOI:10.1038/sj.onc.1205192. PMID:11857081.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Yuryev A، Wennogle LP (2003). "Novel raf kinase protein-protein interactions found by an exhaustive yeast two-hybrid analysis". Genomics. ج. 81 ع. 2: 112–25. DOI:10.1016/S0888-7543(02)00008-3. PMID:12620389.
Mitin NY، Ramocki MB، Zullo AJ، وآخرون (2004). "Identification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localization". J. Biol. Chem. ج. 279 ع. 21: 22353–61. DOI:10.1074/jbc.M312867200. PMID:15031288.
Kho Y، Kim SC، Jiang C، وآخرون (2004). "A tagging-via-substrate technology for detection and proteomics of farnesylated proteins". Proc. Natl. Acad. Sci. U.S.A. ج. 101 ع. 34: 12479–84. Bibcode:2004PNAS..10112479K. DOI:10.1073/pnas.0403413101. PMC:515085. PMID:15308774.
Suzuki Y، Yamashita R، Shirota M، وآخرون (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. ج. 14 ع. 9: 1711–8. DOI:10.1101/gr.2435604. PMC:515316. PMID:15342556.
Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
Barrios-Rodiles M، Brown KR، Ozdamar B، وآخرون (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. ج. 307 ع. 5715: 1621–5. Bibcode:2005Sci...307.1621B. DOI:10.1126/science.1105776. PMID:15761153.

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

[entrez-1] "Entrez Gene: RRAS2 related RAS viral (r-ras) oncogene homolog 2". مؤرشف من الأصل في 2010-12-05.

[pmid2108320-2] Drivas GT، Shih A، Coutavas E، Rush MG، D'Eustachio P (مايو 1990). "Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line". Mol Cell Biol. ج. 10 ع. 4: 1793–8. PMC:362288. PMID:2108320.

[pmid8052619-3] Chan AM، Miki T، Meyers KA، Aaronson SA (سبتمبر 1994). "A human oncogene of the RAS superfamily unmasked by expression cDNA cloning". Proc Natl Acad Sci U S A. ج. 91 ع. 16: 7558–62. Bibcode:1994PNAS...91.7558C. DOI:10.1073/pnas.91.16.7558. PMC:44441. PMID:8052619.

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