TOB1
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هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
An Error has occured retrieving Wikidata item for infobox TOB1 (Transducer of ERBB2, 1) هوَ بروتين يُشَفر بواسطة جين TOB1 في الإنسان.[1][2][3]
الوظيفة
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.الأهمية السريرية
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.المراجع
- ^ "Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation". Molecular and Cellular Biology. 27 (22): 7791–801. Nov 2007. doi:10.1128/MCB.01254-07. PMC 2169145. PMID 17785442. الوسيط
|CitationClass=تم تجاهله (مساعدة) - ^ "Tob, a novel protein that interacts with p185erbB2, is associated with anti-proliferative activity". Oncogene. 12 (4): 705–13. Feb 1996. PMID 8632892. الوسيط
|CitationClass=تم تجاهله (مساعدة) - ^ "Entrez Gene: TOB1 transducer of ERBB2, 1". مؤرشف من الأصل في 05 ديسمبر 2010. الوسيط
|CitationClass=تم تجاهله (مساعدة)
قراءة متعمقة
- "[Monoclonal antibody induces apoptosis against cancer cells]". Nihon Rinsho. Japanese Journal of Clinical Medicine. 60 (3): 451–6. Mar 2002. PMID 11904957. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Cloning and characterization of the mouse tob gene". Gene. 191 (1): 109–13. May 1997. doi:10.1016/S0378-1119(97)00049-8. PMID 9210596. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Tob2, a novel anti-proliferative Tob/BTG1 family member, associates with a component of the CCR4 transcriptional regulatory complex capable of binding cyclin-dependent kinases". Oncogene. 18 (52): 7432–41. Dec 1999. doi:10.1038/sj.onc.1203193. PMID 10602502. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Negative regulation of BMP/Smad signaling by Tob in osteoblasts". Cell. 103 (7): 1085–97. Dec 2000. doi:10.1016/S0092-8674(00)00211-7. PMID 11163184. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "A serine/threonine kinase p90rsk1 phosphorylates the anti-proliferative protein Tob". Genes to Cells. 6 (2): 131–8. Feb 2001. doi:10.1046/j.1365-2443.2001.00406.x. PMID 11260258. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Tob-mediated cross-talk between MARCKS phosphorylation and ErbB-2 activation". Biochemical and Biophysical Research Communications. 283 (2): 273–7. May 2001. doi:10.1006/bbrc.2001.4773. PMID 11327693. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Association of ANA, a member of the antiproliferative Tob family proteins, with a Caf1 component of the CCR4 transcriptional regulatory complex". Japanese Journal of Cancer Research. 92 (6): 592–6. Jun 2001. doi:10.1111/j.1349-7006.2001.tb01135.x. PMID 11429045. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells". Nature Immunology. 2 (12): 1174–82. Dec 2001. doi:10.1038/ni730. PMID 11694881. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation". Genes & Development. 16 (11): 1356–70. Jun 2002. doi:10.1101/gad.962802. PMC 186319. PMID 12050114. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Antiproliferative proteins of the BTG/Tob family are degraded by the ubiquitin-proteasome system". European Journal of Biochemistry / FEBS. 269 (14): 3596–604. Jul 2002. doi:10.1046/j.1432-1033.2002.03052.x. PMID 12135500. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Identification of the Anti-proliferative protein Tob as a MAPK substrate". The Journal of Biological Chemistry. 277 (40): 37783–7. Oct 2002. doi:10.1074/jbc.M204506200. PMID 12151396. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Tob proteins enhance inhibitory Smad-receptor interactions to repress BMP signaling". Mechanisms of Development. 120 (5): 629–37. May 2003. doi:10.1016/S0925-4773(03)00020-0. PMID 12782279. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Alteration of expression or phosphorylation status of tob, a novel tumor suppressor gene product, is an early event in lung cancer". Cancer Letters. 202 (1): 71–9. Dec 2003. doi:10.1016/j.canlet.2003.08.019. PMID 14643028. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Regulation of subcellular localization of the antiproliferative protein Tob by its nuclear export signal and bipartite nuclear localization signal sequences". Experimental Cell Research. 295 (1): 59–65. Apr 2004. doi:10.1016/j.yexcr.2003.12.016. PMID 15051490. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Nuclear localization of Tob is important for regulation of its antiproliferative activity". Oncogene. 23 (39): 6630–8. Aug 2004. doi:10.1038/sj.onc.1207890. PMID 15235587. الوسيط
|CitationClass=تم تجاهله (مساعدة) - "Interaction of anti-proliferative protein Tob with poly(A)-binding protein and inducible poly(A)-binding protein: implication of Tob in translational control". Genes to Cells. 10 (2): 151–63. Feb 2005. doi:10.1111/j.1365-2443.2005.00826.x. PMID 15676026. الوسيط
|CitationClass=تم تجاهله (مساعدة)
