TBC1D4
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هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
An Error has occured retrieving Wikidata item for infobox TBC1D4 (TBC1 domain family member 4) هوَ بروتين يُشَفر بواسطة جين TBC1D4 في الإنسان.[1][2][3][4][5][6][7][3][8][9]
الوظيفة

الأهمية السريرية

المراجع
- ^ "AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain". The Biochemical Journal. 391 (Pt 1): 87–93. Oct 2005. doi:10.1042/BJ20050887. PMC 1237142. PMID 15971998. الوسيط
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تم تجاهله (مساعدة) - ^ "Candidate genes required for embryonic development: a comparative analysis of distal mouse chromosome 14 and human chromosome 13q22". Genomics. 79 (2): 154–61. Feb 2002. doi:10.1006/geno.2002.6692. PMID 11829485. الوسيط
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تم تجاهله (مساعدة) - ↑ أ ب "Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic". Am. J. Physiol. Endocrinol. Metab. 295 (1): E29–37. 2008. doi:10.1152/ajpendo.90331.2008. PMC 2493596. PMID 18477703. الوسيط
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تم تجاهله (مساعدة) - ^ "Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation". The Journal of Biological Chemistry. 278 (17): 14599–602. Apr 2003. doi:10.1074/jbc.C300063200. PMID 12637568. الوسيط
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تم تجاهله (مساعدة) - ^ "Upregulation of the transcript level of GTPase activating protein KIAA0603 in T cells from patients with atopic dermatitis". FEBS Letters. 572 (1–3): 135–40. Aug 2004. doi:10.1016/j.febslet.2004.07.023. PMID 15304337. الوسيط
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تم تجاهله (مساعدة) - ^ "A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain". The Journal of Biological Chemistry. 277 (25): 22115–8. Jun 2002. doi:10.1074/jbc.C200198200. PMID 11994271. الوسيط
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تم تجاهله (مساعدة) - ^ "Entrez Gene: TBC1D4 TBC1 domain family, member 4". مؤرشف من الأصل في 05 ديسمبر 2010. الوسيط
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تم تجاهله (مساعدة) - ^ "A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain". The Journal of Biological Chemistry. 277 (25): 22115–8. Jun 2002. doi:10.1074/jbc.C200198200. PMID 11994271. الوسيط
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تم تجاهله (مساعدة) - ^ "Calmodulin-binding domain of AS160 regulates contraction- but not insulin-stimulated glucose uptake in skeletal muscle". Diabetes. 56 (12): 2854–62. Dec 2007. doi:10.2337/db07-0681. PMID 17717281. الوسيط
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تم تجاهله (مساعدة)
قراءة متعمقة
- "Mice with AS160/TBC1D4-Thr649Ala knockin mutation are glucose intolerant with reduced insulin sensitivity and altered GLUT4 trafficking". Cell Metabolism. 13 (1): 68–79. 2011. doi:10.1016/j.cmet.2010.12.005. PMC 3081066. PMID 21195350. الوسيط
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تم تجاهله (مساعدة) - "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 5 (1): 31–9. Feb 1998. doi:10.1093/dnares/5.1.31. PMID 9628581. الوسيط
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تم تجاهله (مساعدة) - "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs". Genome Research. 12 (11): 1773–84. Nov 2002. doi:10.1101/gr.406902. PMC 187542. PMID 12421765. الوسيط
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تم تجاهله (مساعدة) - "Immunomic analysis of human sarcoma". Proceedings of the National Academy of Sciences of the United States of America. 100 (5): 2651–6. Mar 2003. doi:10.1073/pnas.0437972100. PMC 151395. PMID 12601173. الوسيط
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تم تجاهله (مساعدة) - "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. Aug 2004. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935. الوسيط
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تم تجاهله (مساعدة) - "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Current Biology. 14 (16): 1436–50. Aug 2004. doi:10.1016/j.cub.2004.07.051. PMID 15324660. الوسيط
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تم تجاهله (مساعدة) - "Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects". Diabetes. 54 (6): 1692–7. Jun 2005. doi:10.2337/diabetes.54.6.1692. PMID 15919790. الوسيط
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تم تجاهله (مساعدة) - "Global phosphoproteome of HT-29 human colon adenocarcinoma cells". Journal of Proteome Research. 4 (4): 1339–46. 2005. doi:10.1021/pr050048h. PMID 16083285. الوسيط
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تم تجاهله (مساعدة) - "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. Oct 2006. doi:10.1038/nbt1240. PMID 16964243. الوسيط
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تم تجاهله (مساعدة) - "AS160 phosphorylation is associated with activation of alpha2beta2gamma1- but not alpha2beta2gamma3-AMPK trimeric complex in skeletal muscle during exercise in humans". American Journal of Physiology. Endocrinology and Metabolism. 292 (3): E715-22. Mar 2007. doi:10.1152/ajpendo.00380.2006. PMID 17077344. الوسيط
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تم تجاهله (مساعدة) - "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. Nov 2006. doi:10.1016/j.cell.2006.09.026. PMID 17081983. الوسيط
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تم تجاهله (مساعدة) - "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. 2007. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. الوسيط
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تم تجاهله (مساعدة) - "Resistance exercise and insulin regulate AS160 and interaction with 14-3-3 in human skeletal muscle". Diabetes. 56 (6): 1608–14. Jun 2007. doi:10.2337/db06-1398. PMID 17369524. الوسيط
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تم تجاهله (مساعدة) - "Effects of endurance exercise training on insulin signaling in human skeletal muscle: interactions at the level of phosphatidylinositol 3-kinase, Akt, and AS160". Diabetes. 56 (8): 2093–102. Aug 2007. doi:10.2337/db06-1698. PMID 17513702. الوسيط
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تم تجاهله (مساعدة)
