PRKCH

An Error has occured retrieving Wikidata item for infobox PRKCH‏ (Protein kinase C eta) هوَ بروتين يُشَفر بواسطة جين PRKCH في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ "Entrez Gene: PRKCH protein kinase C, eta". مؤرشف من الأصل في 2010-03-07.
^ Bacher N، Zisman Y، Berent E، Livneh E (أبريل 1992). "Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart". Mol Cell Biol. ج. 12 ع. 3: 1404. PMC:369574. PMID:1545821.
^ Bacher N، Zisman Y، Berent E، Livneh E (فبراير 1991). "Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart". Mol Cell Biol. ج. 11 ع. 1: 126–33. PMC:359602. PMID:1986216.

قراءة متعمقة

Greif H، Ben-Chaim J، Shimon T، وآخرون (1992). "The protein kinase C-related PKC-L(eta) gene product is localized in the cell nucleus". Mol. Cell. Biol. ج. 12 ع. 3: 1304–11. PMC:369563. PMID:1545811.
Liyanage M، Frith D، Livneh E، Stabel S (1992). "Protein kinase C group B members PKC-delta, -epsilon, -zeta and PKC-L(eta). Comparison of properties of recombinant proteins in vitro and in vivo". Biochem. J. ج. 283 ع. 3: 781–7. PMC:1130954. PMID:1590767.
Ruegg CL، Strand M (1991). "A synthetic peptide with sequence identity to the transmembrane protein GP41 of HIV-1 inhibits distinct lymphocyte activation pathways dependent on protein kinase C and intracellular calcium influx". Cell. Immunol. ج. 137 ع. 1: 1–13. DOI:10.1016/0008-8749(91)90051-C. PMID:1832084.
Chowdhury IH، Koyanagi Y، Kobayashi S، وآخرون (1990). "The phorbol ester TPA strongly inhibits HIV-1-induced syncytia formation but enhances virus production: possible involvement of protein kinase C pathway". Virology. ج. 176 ع. 1: 126–32. DOI:10.1016/0042-6822(90)90237-L. PMID:1970444.
Ruegg CL، Strand M (1990). "Inhibition of protein kinase C and anti-CD3-induced Ca2+ influx in Jurkat T cells by a synthetic peptide with sequence identity to HIV-1 gp41". J. Immunol. ج. 144 ع. 10: 3928–35. PMID:2139676.
Jakobovits A، Rosenthal A، Capon DJ (1990). "Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C." EMBO J. ج. 9 ع. 4: 1165–70. PMC:551792. PMID:2182321.
Fields AP، Bednarik DP، Hess A، May WS (1988). "Human immunodeficiency virus induces phosphorylation of its cell surface receptor". Nature. ج. 333 ع. 6170: 278–80. DOI:10.1038/333278a0. PMID:3259291.
Chirmule N، Goonewardena H، Pahwa S، وآخرون (1995). "HIV-1 envelope glycoproteins induce activation of activated protein-1 in CD4+ T cells". J. Biol. Chem. ج. 270 ع. 33: 19364–9. DOI:10.1074/jbc.270.33.19364. PMID:7642615.
Ward NE، Gravitt KR، O'Brian CA (1995). "Inhibition of protein kinase C by a synthetic peptide corresponding to cytoplasmic domain residues 828-848 of the human immunodeficiency virus type 1 envelope glycoprotein". Cancer Lett. ج. 88 ع. 1: 37–40. DOI:10.1016/0304-3835(94)03610-U. PMID:7850771.
Palmer RH، Ridden J، Parker PJ (1995). "Identification of multiple, novel, protein kinase C-related gene products". FEBS Lett. ج. 356 ع. 1: 5–8. DOI:10.1016/0014-5793(94)01202-4. PMID:7988719.
Gupta S، Aggarwal S، Kim C، Gollapudi S (1994). "Human immunodeficiency virus-1 recombinant gp120 induces changes in protein kinase C isozymes--a preliminary report". Int. J. Immunopharmacol. ج. 16 ع. 3: 197–204. DOI:10.1016/0192-0561(94)90013-2. PMID:8206685.
Parada NA، Cruikshank WW، Danis HL، وآخرون (1996). "IL-16- and other CD4 ligand-induced migration is dependent upon protein kinase C.". Cell. Immunol. ج. 168 ع. 1: 100–6. DOI:10.1006/cimm.1996.0054. PMID:8599832.
Denning MF، Dlugosz AA، Threadgill DW، وآخرون (1996). "Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta". J. Biol. Chem. ج. 271 ع. 10: 5325–31. DOI:10.1074/jbc.271.10.5325. PMID:8621384.
Ueda E، Ohno S، Kuroki T، وآخرون (1996). "The eta isoform of protein kinase C mediates transcriptional activation of the human transglutaminase 1 gene". J. Biol. Chem. ج. 271 ع. 16: 9790–4. DOI:10.1074/jbc.271.16.9790. PMID:8621660.
Conant K، Ma M، Nath A، Major EO (1996). "Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes". J. Virol. ج. 70 ع. 3: 1384–9. PMC:189957. PMID:8627654.
Holmes AM (1996). "In vitro phosphorylation of human immunodeficiency virus type 1 Tat protein by protein kinase C: evidence for the phosphorylation of amino acid residue serine-46". Arch. Biochem. Biophys. ج. 335 ع. 1: 8–12. DOI:10.1006/abbi.1996.0476. PMID:8914829.
Borgatti P، Zauli G، Cantley LC، Capitani S (1998). "Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells". Biochem. Biophys. Res. Commun. ج. 242 ع. 2: 332–7. DOI:10.1006/bbrc.1997.7877. PMID:9446795.
Zidovetzki R، Wang JL، Chen P، وآخرون (1998). "Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP-dependent protein kinase pathways". AIDS Res. Hum. Retroviruses. ج. 14 ع. 10: 825–33. DOI:10.1089/aid.1998.14.825. PMID:9671211.

هذه بذرة مقالة عن جين على كروموسوم 14 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[1] "Entrez Gene: PRKCH protein kinase C, eta". مؤرشف من الأصل في 2010-03-07.

[2] Bacher N، Zisman Y، Berent E، Livneh E (أبريل 1992). "Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart". Mol Cell Biol. ج. 12 ع. 3: 1404. PMC:369574. PMID:1545821.

[3] Bacher N، Zisman Y، Berent E، Livneh E (فبراير 1991). "Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart". Mol Cell Biol. ج. 11 ع. 1: 126–33. PMC:359602. PMID:1986216.

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