TBX21

An Error has occured retrieving Wikidata item for infobox TBX21‏ (T-box 21) هوَ بروتين يُشَفر بواسطة جين TBX21 في الإنسان.

الوظيفة

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الأهمية السريرية

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قراءة متعمقة

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• "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. Oct 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• "A novel transcription factor, T-bet, directs Th1 lineage commitment". Cell. 100 (6): 655–69. Mar 2000. doi:10.1016/S0092-8674(00)80702-3. PMID 10761931.
• "Cloning and characterization of a new member of the T-box gene family". Genomics. 70 (1): 41–8. Nov 2000. doi:10.1006/geno.2000.6361. PMID 11087660.
• "Developmental expression of the T-box transcription factor T-bet/Tbx21 during mouse embryogenesis". Mechanisms of Development. 116 (1–2): 157–60. Aug 2002. doi:10.1016/S0925-4773(02)00114-4. PMID 12128215.
• "Association analysis of novel TBX21 variants with asthma phenotypes". Human Mutation. 22 (3): 257. Sep 2003. doi:10.1002/humu.9169. PMID 12938094.
• "Different antigens trigger different Th1/Th2 reactions in neonatal mononuclear cells (MNCs) relating to T-bet/GATA-3 expression". Journal of Leukocyte Biology. 74 (5): 952–8. Nov 2003. doi:10.1189/jlb.0902474. PMID 12960249.
• "Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities". The Journal of Allergy and Clinical Immunology. 113 (5): 987–94. May 2004. doi:10.1016/j.jaci.2004.02.004. PMID 15131585.
• "Identification of a novel type 1 diabetes susceptibility gene, T-bet". Human Genetics. 115 (3): 177–84. Aug 2004. doi:10.1007/s00439-004-1146-2. PMID 15241679.
• "TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids". Proceedings of the National Academy of Sciences of the United States of America. 101 (52): 18099–104. Dec 2004. doi:10.1073/pnas.0408532102. PMC 539815. PMID 15604153.
• "Expression of the T-cell transcription factors, GATA-3 and T-bet, in the neoplastic cells of Hodgkin lymphomas". The American Journal of Pathology. 166 (1): 127–34. Jan 2005. doi:10.1016/S0002-9440(10)62238-9. PMC 1602286. PMID 15632006.
• "T-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-site". Proceedings of the National Academy of Sciences of the United States of America. 102 (6): 2034–9. Feb 2005. doi:10.1073/pnas.0409510102. PMC 548570. PMID 15684083.
• "T-bet, a T cell-associated transcription factor, is expressed in Hodgkin's lymphoma". Human Pathology. 36 (1): 10–5. Jan 2005. doi:10.1016/j.humpath.2004.10.006. PMID 15712176.
• "HIV-1 Tat modulates T-bet expression and induces Th1 type of immune response". Biochemical and Biophysical Research Communications. 329 (2): 706–12. Apr 2005. doi:10.1016/j.bbrc.2005.02.042. PMID 15737643.
• "Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma". Human Genetics. 117 (1): 16–26. Jun 2005. doi:10.1007/s00439-005-1285-0. PMID 15806396.
• "Female steroid hormones use signal transducers and activators of transcription protein-mediated pathways to modulate the expression of T-bet in epithelial cells: a mechanism for local immune regulation in the human reproductive tract". Molecular Endocrinology. 19 (8): 2047–59. Aug 2005. doi:10.1210/me.2004-0489. PMID 15860546.
• "Transcription factor expression in B-cell precursor-leukemia cell lines: preferential expression of T-bet". Leukemia Research. 29 (7): 841–8. Jul 2005. doi:10.1016/j.leukres.2004.12.010. PMID 15927679.
• "Transcription factor Foxo1 is a negative regulator of natural killer cell maturation and function". Immunity. 42 (3): 457–70. Mar 2015. doi:10.1016/j.immuni.2015.02.006. PMC 4400836. PMID 25769609.
• "T-bet polymorphisms are associated with asthma and airway hyperresponsiveness". American Journal of Respiratory and Critical Care Medicine. 173 (1): 64–70. Jan 2006. doi:10.1164/rccm.200503-505OC. PMC 2662983. PMID 16179640.

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