TLE2
من أرابيكا، الموسوعة العربية الحرة
المزيد من اللغات
المزيد من الإجراءات
An Error has occured retrieving Wikidata item for infobox TLE2 (Transducin like enhancer of split 2) هوَ بروتين يُشَفر بواسطة جين TLE2 في الإنسان.[1][2]
الوظيفة
![[أيقونة]](/%D9%85%D9%84%D9%81:Crystal_xedit.svg){kind=small} | هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
| هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
- ^ "Entrez Gene: TLE2 transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)". مؤرشف من الأصل في 2010-12-05.
- ^ Liu Y، Dehni G، Purcell KJ، Sokolow J، Carcangiu ML، Artavanis-Tsakonas S، Stifani S (أكتوبر 1996). "Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia". Genomics. ج. 31 ع. 1: 58–64. DOI:10.1006/geno.1996.0009. PMID:8808280.
قراءة متعمقة
- Stifani S، Blaumueller CM، Redhead NJ، وآخرون (1993). "Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins". Nat. Genet. ج. 2 ع. 2: 119–27. DOI:10.1038/ng1092-119. PMID:1303260.
- Miyasaka H، Choudhury BK، Hou EW، Li SS (1993). "Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein". Eur. J. Biochem. ج. 216 ع. 1: 343–52. DOI:10.1111/j.1432-1033.1993.tb18151.x. PMID:8365415.
- Palaparti A، Baratz A، Stifani S (1997). "The Groucho/transducin-like enhancer of split transcriptional repressors interact with the genetically defined amino-terminal silencing domain of histone H3". J. Biol. Chem. ج. 272 ع. 42: 26604–10. DOI:10.1074/jbc.272.42.26604. PMID:9334241.
- Grbavec D، Lo R، Liu Y، وآخرون (1999). "Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms". Biochem. J. ج. 337 ع. 1: 13–7. DOI:10.1042/0264-6021:3370013. PMC:1219929. PMID:9854018.
- Grbavec D، Lo R، Liu Y، Stifani S (1999). "Transducin-like Enhancer of split 2, a mammalian homologue of Drosophila Groucho, acts as a transcriptional repressor, interacts with Hairy/Enhancer of split proteins, and is expressed during neuronal development". Eur. J. Biochem. ج. 258 ع. 2: 339–49. DOI:10.1046/j.1432-1327.1998.2580339.x. PMID:9874198.
- Ren B، Chee KJ، Kim TH، Maniatis T (1999). "PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins". Genes Dev. ج. 13 ع. 1: 125–37. DOI:10.1101/gad.13.1.125. PMC:316372. PMID:9887105.
- Javed A، Guo B، Hiebert S، وآخرون (2000). "Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription". J. Cell Sci. ج. 113 ع. 12: 2221–31. PMID:10825294.
- Brantjes H، Roose J، van De Wetering M، Clevers H (2001). "All Tcf HMG box transcription factors interact with Groucho-related co-repressors". Nucleic Acids Res. ج. 29 ع. 7: 1410–9. DOI:10.1093/nar/29.7.1410. PMC:31284. PMID:11266540.
- Dintilhac A، Bernués J (2002). "HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences". J. Biol. Chem. ج. 277 ع. 9: 7021–8. DOI:10.1074/jbc.M108417200. PMID:11748221.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
- Grimwood J، Gordon LA، Olsen A، وآخرون (2004). "The DNA sequence and biology of human chromosome 19". Nature. ج. 428 ع. 6982: 529–35. Bibcode:2004Natur.428..529G. DOI:10.1038/nature02399. PMID:15057824.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Rual JF، Venkatesan K، Hao T، وآخرون (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. ج. 437 ع. 7062: 1173–8. Bibcode:2005Natur.437.1173R. DOI:10.1038/nature04209. PMID:16189514.
- Higa LA، Wu M، Ye T، وآخرون (2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation". Nat. Cell Biol. ج. 8 ع. 11: 1277–83. DOI:10.1038/ncb1490. PMID:17041588.
