CDC34

An Error has occured retrieving Wikidata item for infobox CDC34‏ (Cell division cycle 34) هوَ بروتين يُشَفر بواسطة جين CDC34 في إنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ "Entrez Gene: CDC34 cell division cycle 34 homolog (S. cerevisiae)". مؤرشف من الأصل في 2010-12-05.
^ Plon SE، Leppig KA، Do HN، Groudine M (ديسمبر 1993). "Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeast". Proc Natl Acad Sci U S A. ج. 90 ع. 22: 10484–8. Bibcode:1993PNAS...9010484P. DOI:10.1073/pnas.90.22.10484. PMC:47801. PMID:8248134.
^ Gazdoiu S، Yamoah K، Wu K، Escalante CR، Tappin I، Bermudez V، Aggarwal AK، Hurwitz J، Pan ZQ (أكتوبر 2005). "Proximity-induced activation of human Cdc34 through heterologous dimerization". Proc Natl Acad Sci U S A. ج. 102 ع. 42: 15053–8. Bibcode:2005PNAS..10215053G. DOI:10.1073/pnas.0507646102. PMC:1242854. PMID:16210246.

قراءة متعمقة

King RW، Deshaies RJ، Peters JM، Kirschner MW (1997). "How proteolysis drives the cell cycle". Science. ج. 274 ع. 5293: 1652–9. Bibcode:1996Sci...274.1652K. DOI:10.1126/science.274.5293.1652. PMID:8939846.
Pagano M (1997). "Cell cycle regulation by the ubiquitin pathway". FASEB J. ج. 11 ع. 13: 1067–75. PMID:9367342.
Lisztwan J، Marti A، Sutterlüty H، وآخرون (1998). "Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway". EMBO J. ج. 17 ع. 2: 368–83. DOI:10.1093/emboj/17.2.368. PMC:1170388. PMID:9430629.
Song A، Wang Q، Goebl MG، Harrington MA (1998). "Phosphorylation of nuclear MyoD is required for its rapid degradation". Mol. Cell. Biol. ج. 18 ع. 9: 4994–9. PMC:109084. PMID:9710583.
Gonen H، Bercovich B، Orian A، وآخرون (1999). "Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkappaBalpha". J. Biol. Chem. ج. 274 ع. 21: 14823–30. DOI:10.1074/jbc.274.21.14823. PMID:10329681.
Pati D، Meistrich ML، Plon SE (1999). "Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis". Mol. Cell. Biol. ج. 19 ع. 7: 5001–13. DOI:10.1128/mcb.19.7.5001. PMC:84326. PMID:10373550.
Seol JH، Feldman RM، Zachariae W، وآخرون (1999). "Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34". Genes Dev. ج. 13 ع. 12: 1614–26. DOI:10.1101/gad.13.12.1614. PMC:316801. PMID:10385629.
Read MA، Brownell JE، Gladysheva TB، وآخرون (2000). "Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha". Mol. Cell. Biol. ج. 20 ع. 7: 2326–33. DOI:10.1128/MCB.20.7.2326-2333.2000. PMC:85397. PMID:10713156.
Reymond F، Wirbelauer C، Krek W (2000). "Association of human ubiquitin-conjugating enzyme CDC34 with the mitotic spindle in anaphase". J. Cell Sci. ج. 113 ع. 10: 1687–94. PMID:10769200.
Charrasse S، Carena I، Brondani V، وآخرون (2000). "Degradation of B-Myb by ubiquitin-mediated proteolysis: involvement of the Cdc34-SCF(p45Skp2) pathway". Oncogene. ج. 19 ع. 26: 2986–95. DOI:10.1038/sj.onc.1203618. PMID:10871850.
Strack P، Caligiuri M، Pelletier M، وآخرون (2000). "SCF(beta-TRCP) and phosphorylation dependent ubiquitinationof I kappa B alpha catalyzed by Ubc3 and Ubc4". Oncogene. ج. 19 ع. 31: 3529–36. DOI:10.1038/sj.onc.1203647. PMID:10918611.
Duan W، Sun B، Li TW، وآخرون (2001). "Cloning and characterization of AWP1, a novel protein that associates with serine/threonine kinase PRK1 in vivo". Gene. ج. 256 ع. 1–2: 113–21. DOI:10.1016/S0378-1119(00)00365-6. PMID:11054541.
Block K، Boyer TG، Yew PR (2001). "Phosphorylation of the human ubiquitin-conjugating enzyme, CDC34, by casein kinase 2". J. Biol. Chem. ج. 276 ع. 44: 41049–58. DOI:10.1074/jbc.M106453200. PMID:11546811.
Wu K، Chen A، Tan P، Pan ZQ (2002). "The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34". J. Biol. Chem. ج. 277 ع. 1: 516–27. DOI:10.1074/jbc.M108008200. PMID:11675391.
Kiernan RE، Emiliani S، Nakayama K، وآخرون (2001). "Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome". Mol. Cell. Biol. ج. 21 ع. 23: 7956–70. DOI:10.1128/MCB.21.23.7956-7970.2001. PMC:99964. PMID:11689688.
Semplici F، Meggio F، Pinna LA، Oliviero S (2002). "CK2-dependent phosphorylation of the E2 ubiquitin conjugating enzyme UBC3B induces its interaction with beta-TrCP and enhances beta-catenin degradation". Oncogene. ج. 21 ع. 25: 3978–87. DOI:10.1038/sj.onc.1205574. PMID:12037680.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

[entrez-1] "Entrez Gene: CDC34 cell division cycle 34 homolog (S. cerevisiae)". مؤرشف من الأصل في 2010-12-05.

[pmid8248134-2] Plon SE، Leppig KA، Do HN، Groudine M (ديسمبر 1993). "Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeast". Proc Natl Acad Sci U S A. ج. 90 ع. 22: 10484–8. Bibcode:1993PNAS...9010484P. DOI:10.1073/pnas.90.22.10484. PMC:47801. PMID:8248134.

[pmid16210246-3] Gazdoiu S، Yamoah K، Wu K، Escalante CR، Tappin I، Bermudez V، Aggarwal AK، Hurwitz J، Pan ZQ (أكتوبر 2005). "Proximity-induced activation of human Cdc34 through heterologous dimerization". Proc Natl Acad Sci U S A. ج. 102 ع. 42: 15053–8. Bibcode:2005PNAS..10215053G. DOI:10.1073/pnas.0507646102. PMC:1242854. PMID:16210246.

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