RAB8A

An Error has occured retrieving Wikidata item for infobox RAB8A‏ (RAB8A, member RAS oncogene family) هوَ بروتين يُشَفر بواسطة جين RAB8A في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ "Entrez Gene: RAB8A RAB8A, member RAS oncogene family". مؤرشف من الأصل في 2010-12-05.
^ Huber LA، Pimplikar S، Parton RG، Virta H، Zerial M، Simons K (أكتوبر 1993). "Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane". The Journal of Cell Biology. ج. 123 ع. 1: 35–45. DOI:10.1083/jcb.123.1.35. PMC:2119815. PMID:8408203.
^ Nimmo ER، Sanders PG، Padua RA، Hughes D، Williamson R، Johnson KJ (أغسطس 1991). "The MEL gene: a new member of the RAB/YPT class of RAS-related genes". Oncogene. ج. 6 ع. 8: 1347–51. PMID:1886711.

قراءة متعمقة

Newport J، Roemer MI (مارس 1975). "Comparative perinatal mortality under medical care foundations and other delivery models". Inquiry. ج. 12 ع. 1: 10–7. PMID:123217.
Nimmo E، Padua RA، Hughes D، Brook JD، Williamson R، Johnson KJ (مارس 1989). "Confirmation and refinement of the localisation of the c-MEL locus on chromosome 19 by physical and genetic mapping". Human Genetics. ج. 81 ع. 4: 382–4. DOI:10.1007/BF00283697. PMID:2564840.
Zahraoui A، Joberty G، Arpin M، Fontaine JJ، Hellio R، Tavitian A، Louvard D (يناير 1994). "A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells". The Journal of Cell Biology. ج. 124 ع. 1–2: 101–15. DOI:10.1083/jcb.124.1.101. PMC:2119893. PMID:8294494.
Joberty G، Tavitian A، Zahraoui A (سبتمبر 1993). "Isoprenylation of Rab proteins possessing a C-terminal CaaX motif". FEBS Letters. ج. 330 ع. 3: 323–8. DOI:10.1016/0014-5793(93)80897-4. PMID:8375503.
Ren M، Zeng J، De Lemos-Chiarandini C، Rosenfeld M، Adesnik M، Sabatini DD (مايو 1996). "In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase". Proceedings of the National Academy of Sciences of the United States of America. ج. 93 ع. 10: 5151–5. DOI:10.1073/pnas.93.10.5151. PMC:39423. PMID:8643544.
Bähler M، Kehrer I، Gordon L، Stoffler HE، Olsen AS (يوليو 1997). "Physical mapping of human myosin-IXB (MYO9B), the human orthologue of the rat myosin myr 5, to chromosome 19p13.1". Genomics. ج. 43 ع. 1: 107–9. DOI:10.1006/geno.1997.4776. PMID:9226381.
Wilson AL، Erdman RA، Castellano F، Maltese WA (أغسطس 1998). "Prenylation of Rab8 GTPase by type I and type II geranylgeranyl transferases". The Biochemical Journal. 333 ( Pt 3) ع. Pt 3: 497–504. PMC:1219609. PMID:9677305.
Bao S، Zhu J، Garvey WT (نوفمبر 1998). "Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects". Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme. ج. 30 ع. 11: 656–62. DOI:10.1055/s-2007-978953. PMID:9918381.
Shisheva A، Chinni SR، DeMarco C (سبتمبر 1999). "General role of GDP dissociation inhibitor 2 in membrane release of Rab proteins: modulations of its functional interactions by in vitro and in vivo structural modifications". Biochemistry. ج. 38 ع. 36: 11711–21. DOI:10.1021/bi990200r. PMID:10512627.
Hattula K، Peränen J (2001). "FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis". Current Biology. ج. 10 ع. 24: 1603–6. DOI:10.1016/S0960-9822(00)00864-2. PMID:11137014.
Kuroda TS، Fukuda M، Ariga H، Mikoshiba K (مارس 2002). "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain". The Journal of Biological Chemistry. ج. 277 ع. 11: 9212–8. DOI:10.1074/jbc.M112414200. PMID:11773082.
Hattula K، Furuhjelm J، Arffman A، Peränen J (سبتمبر 2002). "A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport". Molecular Biology of the Cell. ج. 13 ع. 9: 3268–80. DOI:10.1091/mbc.E02-03-0143. PMC:124888. PMID:12221131.
Fukuda M (أبريل 2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". The Journal of Biological Chemistry. ج. 278 ع. 17: 15373–80. DOI:10.1074/jbc.M212341200. PMID:12578829.
Lau AS، Mruk DD (أبريل 2003). "Rab8B GTPase and junction dynamics in the testis". Endocrinology. ج. 144 ع. 4: 1549–63. DOI:10.1210/en.2002-220893. PMID:12639940.
Linder MD، Uronen RL، Hölttä-Vuori M، van der Sluijs P، Peränen J، Ikonen E (يناير 2007). "Rab8-dependent recycling promotes endosomal cholesterol removal in normal and sphingolipidosis cells". Molecular Biology of the Cell. ج. 18 ع. 1: 47–56. DOI:10.1091/mbc.E06-07-0575. PMC:1751315. PMID:17050734.

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

[entrez-1] "Entrez Gene: RAB8A RAB8A, member RAS oncogene family". مؤرشف من الأصل في 2010-12-05.

[pmid8408203-2] Huber LA، Pimplikar S، Parton RG، Virta H، Zerial M، Simons K (أكتوبر 1993). "Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane". The Journal of Cell Biology. ج. 123 ع. 1: 35–45. DOI:10.1083/jcb.123.1.35. PMC:2119815. PMID:8408203.

[pmid1886711-3] Nimmo ER، Sanders PG، Padua RA، Hughes D، Williamson R، Johnson KJ (أغسطس 1991). "The MEL gene: a new member of the RAB/YPT class of RAS-related genes". Oncogene. ج. 6 ع. 8: 1347–51. PMID:1886711.

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