DLK1

An Error has occured retrieving Wikidata item for infobox DLK1‏ (Delta like non-canonical Notch ligand 1) هوَ بروتين يُشَفر بواسطة جين DLK1 في الإنسان.^[1]^[2]^[3]^[4]^[5]^[6]

الوظيفة

الأهمية السريرية

المراجع

^ Wang Y، Sul HS (2009). "Pref-1 Regulates Mesenchymal Cell Commitment and Differentiation through Sox9". Cell Metabolism. ج. 9 ع. 3: 287–302. DOI:10.1016/j.cmet.2009.01.013. PMC:2673480. PMID:19254573.
^ EntrezGene 8788
^ Laborda J (2000). "The role of the epidermal growth factor-like protein dlk in cell differentiation". Histology and histopathology. ج. 15 ع. 1: 119–29. PMID:10668203.
^ Jensen CH، Krogh TN، Højrup P، Clausen PP، Skjødt K، Larsson LI، Enghild JJ، Teisner B (1994). "Protein Structure of Fetal Antigen 1 (FA1). A Novel Circulating Human Epidermal-Growth-Factor-Like Protein Expressed in Neuroendocrine Tumors and its Relation to the Gene Products of Dlk and pG2". European Journal of Biochemistry. ج. 225 ع. 1: 83–92. DOI:10.1111/j.1432-1033.1994.00083.x. PMID:7925474.
^ Adipogenesis في المكتبة الوطنية الأمريكية للطب نظام فهرسة المواضيع الطبية (MeSH).
^ Laborda J، Sausville EA، Hoffman T، Notario V (1993). "dlk, a Putative Mammalian Homeotic Gene Differentially Expressed in Small Cell Lung Carcinoma and Neuroendocrine Tumor Cell Line". The Journal of Biological Chemistry. ج. 268 ع. 6: 3817–20. PMID:8095043. مؤرشف من الأصل في 2020-03-02.

قراءة متعمقة

Helamn، Lee J.؛ Sack، Nancy؛ Plon، Sharon E.؛ Israel، Mark A. (1990). "The sequence of an adrenal specific human cDNA, pG2". Nucleic Acids Research. ج. 18 ع. 3: 685–685. DOI:10.1093/nar/18.3.685.
Helman، L. J. (1987). "Molecular Markers of Neuroendocrine Development and Evidence of Environmental Regulation". Proceedings of the National Academy of Sciences. ج. 84 ع. 8: 2336–9. DOI:10.1073/pnas.84.8.2336. PMC:304645.
Lee YL، Helman L، Hoffman T، Laborda J (1995). "Dlk, pG2 and Pref-1 mRNAs encode similar proteins belonging to the EGF-like superfamily. Identification of polymorphic variants of this RNA". Biochimica et Biophysica Acta. ج. 1261 ع. 2: 223–32. DOI:10.1016/0167-4781(95)00007-4. PMID:7711066.
Smas CM، Sul HS (1993). "Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation". Cell. ج. 73 ع. 4: 725–34. DOI:10.1016/0092-8674(93)90252-L. PMID:8500166.
Jensen CH، Teisner B، Højrup P، Rasmussen HB، Madsen OD، Nielsen B، Skjødt K (1993). "Studies on the isolation, structural analysis and tissue localization of fetal antigen 1 and its relation to a human adrenal-specific cDNA, pG2". Human Reproduction. ج. 8 ع. 4: 635–41. DOI:10.1093/oxfordjournals.humrep.a138110. PMID:8501199.
Tornehave D، Jensen CH، Teisner B، Larsson LI (1996). "FA1 immunoreactivity in endocrine tumours and during development of the human fetal pancreas; negative correlation with glucagon expression". Histochemistry and Cell Biology. ج. 106 ع. 6: 535–42. DOI:10.1007/BF02473268. PMID:8985741.
Jensen CH، Schroder HD، Teisner B، Laursen I، Brandrup F، Rasmussen HB (1999). "Fetal antigen 1, a member of the epidermal growth factor superfamily, in neurofibromas and serum from patients with neurofibromatosis type 1". British Journal of Dermatology. ج. 140 ع. 6: 1054–9. DOI:10.1046/j.1365-2133.1999.02906.x. PMID:10354070.
Gubina، E.؛ Ruiz-Hidalgo، M.J.؛ Baladrón، V.؛ Laborda، J. (1999). "Assignment of DLK1 to human chromosome band 14q32 by in situ hybridization". Cytogenetic and Genome Research. ج. 84 ع. 3–4: 206–7. DOI:10.1159/000015259.
Jensen CH، Erb K، Westergaard LG، Kliem A، Teisner B (1999). "Fetal antigen 1, an EGF multidomain protein in the sex hormone-producing cells of the gonads and the microenvironment of germ cells". Molecular Human Reproduction. ج. 5 ع. 10: 908–13. DOI:10.1093/molehr/5.10.908. PMID:10508217.
Aguan K، Carvajal JA، Thompson LP، Weiner CP (2000). "Application of a functional genomics approach to identify differentially expressed genes in human myometrium during pregnancy and labour". Molecular Human Reproduction. ج. 6 ع. 12: 1141–5. DOI:10.1093/molehr/6.12.1141. PMID:11101697.
Andersen، M. (2001). "Fetal Antigen 1 in Healthy Adults and Patients with Pituitary Disease: Relation to Physiological, Pathological, and Pharmacological GH Levels". Journal of Clinical Endocrinology & Metabolism. ج. 86 ع. 11: 5465–70. DOI:10.1210/jc.86.11.5465.
Jensen CH، Meyer M، Schroder HD، Kliem A، Zimmer J، Teisner B (2001). "Neurons in the monoaminergic nuclei of the rat and human central nervous system express FA1/dlk". NeuroReport. ج. 12 ع. 18: 3959–63. DOI:10.1097/00001756-200112210-00021. PMID:11742219.
Baladrón V، Ruiz-Hidalgo MJ، Bonvini E، Gubina E، Notario V، Laborda J (2002). "The EGF-like Homeotic Protein dlk Affects Cell Growth and Interacts with Growth-Modulating Molecules in the Yeast Two-Hybrid System". Biochemical and Biophysical Research Communications. ج. 291 ع. 2: 193–204. DOI:10.1006/bbrc.2002.6431. PMID:11846389.
Panin VM، Shao L، Lei L، Moloney DJ، Irvine KD، Haltiwanger RS (2002). "Notch Ligands Are Substrates for Protein O-Fucosyltransferase-1 and Fringe". Journal of Biological Chemistry. ج. 277 ع. 33: 29945–52. DOI:10.1074/jbc.M204445200. PMID:12036964.
Doggett KL، Briggs JA، Linton MF، Fazio S، Head DR، Xie J، Hashimoto Y، Laborda J، Briggs RC (2002). "Retroviral mediated expression of the human myeloid nuclear antigen in a null cell line upregulatesDlk1 expression". Journal of Cellular Biochemistry. ج. 86 ع. 1: 56–66. DOI:10.1002/jcb.10190. PMID:12112016.
Van Limpt VA، Chan AJ، Van Sluis PG، Caron HN، Van Noesel CJ، Versteeg R (2003). "High delta-like 1 expression in a subset of neuroblastoma cell lines corresponds to a differentiated chromaffin cell type". International Journal of Cancer. ج. 105: 61–9. DOI:10.1002/ijc.11047. PMID:12672031.
Abdallah BM، Jensen CH، Gutierrez G، Leslie RG، Jensen TG، Kassem M (2004). "Regulation of Human Skeletal Stem Cells Differentiation by Dlk1/Pref-1". Journal of Bone and Mineral Research. ج. 19 ع. 5: 841–52. DOI:10.1359/JBMR.040118. PMID:15068508.

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

[1] Wang Y، Sul HS (2009). "Pref-1 Regulates Mesenchymal Cell Commitment and Differentiation through Sox9". Cell Metabolism. ج. 9 ع. 3: 287–302. DOI:10.1016/j.cmet.2009.01.013. PMC:2673480. PMID:19254573.

[entrez-2] EntrezGene 8788

[3] Laborda J (2000). "The role of the epidermal growth factor-like protein dlk in cell differentiation". Histology and histopathology. ج. 15 ع. 1: 119–29. PMID:10668203.

[pmid7925474-4] Jensen CH، Krogh TN، Højrup P، Clausen PP، Skjødt K، Larsson LI، Enghild JJ، Teisner B (1994). "Protein Structure of Fetal Antigen 1 (FA1). A Novel Circulating Human Epidermal-Growth-Factor-Like Protein Expressed in Neuroendocrine Tumors and its Relation to the Gene Products of Dlk and pG2". European Journal of Biochemistry. ج. 225 ع. 1: 83–92. DOI:10.1111/j.1432-1033.1994.00083.x. PMID:7925474.

[5] Adipogenesis في المكتبة الوطنية الأمريكية للطب نظام فهرسة المواضيع الطبية (MeSH).

[pmid8095043-6] Laborda J، Sausville EA، Hoffman T، Notario V (1993). "dlk, a Putative Mammalian Homeotic Gene Differentially Expressed in Small Cell Lung Carcinoma and Neuroendocrine Tumor Cell Line". The Journal of Biological Chemistry. ج. 268 ع. 6: 3817–20. PMID:8095043. مؤرشف من الأصل في 2020-03-02.

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