SOCS2
من أرابيكا، الموسوعة العربية الحرة
المزيد من اللغات
المزيد من الإجراءات
An Error has occured retrieving Wikidata item for infobox SOCS2 (Suppressor of cytokine signaling 2) هوَ بروتين يُشَفر بواسطة جين SOCS2 في الإنسان.[1][2][3][4][5][1]
الوظيفة
![[أيقونة]](/%D9%85%D9%84%D9%81:Crystal_xedit.svg){kind=small} | هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
| هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
- ^ أ ب "Entrez Gene: SOCS2 suppressor of cytokine signaling 2". مؤرشف من الأصل في 2010-12-05.
- ^ Dey BR؛ Spence SL؛ Nissley P؛ Furlanetto RW (سبتمبر 1998). "Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor". J. Biol. Chem. ج. 273 ع. 37: 24095–101. DOI:10.1074/jbc.273.37.24095. PMID:9727029.
- ^ Minamoto S؛ Ikegame K؛ Ueno K؛ Narazaki M؛ Naka T؛ Yamamoto H؛ Matsumoto T؛ Saito H؛ Hosoe S؛ Kishimoto T (سبتمبر 1997). "Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3". Biochem Biophys Res Commun. ج. 237 ع. 1: 79–83. DOI:10.1006/bbrc.1997.7080. PMID:9266833.
- ^ Masuhara M؛ Sakamoto H؛ Matsumoto A؛ Suzuki R؛ Yasukawa H؛ Mitsui K؛ Wakioka T؛ Tanimura S؛ Sasaki A؛ Misawa H؛ Yokouchi M؛ Ohtsubo M؛ Yoshimura A (نوفمبر 1997). "Cloning and characterization of novel CIS family genes". Biochem Biophys Res Commun. ج. 239 ع. 2: 439–46. DOI:10.1006/bbrc.1997.7484. PMID:9344848.
- ^ Greenhalgh CJ؛ Bertolino P؛ Asa SL؛ Metcalf D؛ Corbin JE؛ Adams TE؛ Davey HW؛ Nicola NA؛ Hilton DJ؛ Alexander WS (يونيو 2002). "Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)". Mol. Endocrinol. ج. 16 ع. 6: 1394–406. DOI:10.1210/me.16.6.1394. PMID:12040024.
قراءة متعمقة
- Lopaczynski W (1999). "Differential regulation of signaling pathways for insulin and insulin-like growth factor I.". Acta Biochim. Pol. ج. 46 ع. 1: 51–60. PMID:10453981.
- Wang J؛ Campbell IL (2002). "Cytokine signaling in the brain: putting a SOCS in it?". J. Neurosci. Res. ج. 67 ع. 4: 423–7. DOI:10.1002/jnr.10145. PMID:11835308.
- Kile BT، Schulman BA، Alexander WS، وآخرون (2002). "The SOCS box: a tale of destruction and degradation". Trends Biochem. Sci. ج. 27 ع. 5: 235–41. DOI:10.1016/S0968-0004(02)02085-6. PMID:12076535.
- Pezet A؛ Buteau H؛ Kelly PA؛ Edery M (1997). "The last proline of Box 1 is essential for association with JAK2 and functional activation of the prolactin receptor". Mol. Cell. Endocrinol. ج. 129 ع. 2: 199–208. DOI:10.1016/S0303-7207(97)00063-4. PMID:9202403.
- Dey BR؛ Spence SL؛ Nissley P؛ Furlanetto RW (1998). "Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor". J. Biol. Chem. ج. 273 ع. 37: 24095–101. DOI:10.1074/jbc.273.37.24095. PMID:9727029.
- Pezet A؛ Favre H؛ Kelly PA؛ Edery M (1999). "Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling". J. Biol. Chem. ج. 274 ع. 35: 24497–502. DOI:10.1074/jbc.274.35.24497. PMID:10455112.
- Yandava CN؛ Pillari A؛ Drazen JM (1999). "Radiation hybrid and cytogenetic mapping of SOCS1 and SOCS2 to chromosomes 16p13 and 12q, respectively". Genomics. ج. 61 ع. 1: 108–11. DOI:10.1006/geno.1999.5937. PMID:10512686.
- Ram PA؛ Waxman DJ (2000). "SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms". J. Biol. Chem. ج. 274 ع. 50: 35553–61. DOI:10.1074/jbc.274.50.35553. PMID:10585430.
- Metcalf D، Greenhalgh CJ، Viney E، وآخرون (2000). "Gigantism in mice lacking suppressor of cytokine signalling-2". Nature. ج. 405 ع. 6790: 1069–73. DOI:10.1038/35016611. PMID:10890450.
- Shen X؛ Hong F؛ Nguyen VA؛ Gao B (2000). "IL-10 attenuates IFN-alpha-activated STAT1 in the liver: involvement of SOCS2 and SOCS3". FEBS Lett. ج. 480 ع. 2–3: 132–6. DOI:10.1016/S0014-5793(00)01905-0. PMID:11034314.
- Eyckerman S، Verhee A، der Heyden JV، وآخرون (2002). "Design and application of a cytokine-receptor-based interaction trap". Nat. Cell Biol. ج. 3 ع. 12: 1114–9. DOI:10.1038/ncb1201-1114. PMID:11781573.
- Schultheis B، Carapeti-Marootian M، Hochhaus A، وآخرون (2002). "Overexpression of SOCS-2 in advanced stages of chronic myeloid leukemia: possible inadequacy of a negative feedback mechanism". Blood. ج. 99 ع. 5: 1766–75. DOI:10.1182/blood.V99.5.1766. PMID:11861294.
- Blumenstein M؛ Bowen-Shauver JM؛ Keelan JA؛ Mitchell MD (2002). "Identification of suppressors of cytokine signaling (SOCS) proteins in human gestational tissues: differential regulation is associated with the onset of labor". J. Clin. Endocrinol. Metab. ج. 87 ع. 3: 1094–7. DOI:10.1210/jc.87.3.1094. PMID:11889171.
- Biener E، Maurice S، Sandowski Y، وآخرون (2003). "Recombinant human CIS2 (SOCS2) protein: subcloning, expression, purification, and characterization". Protein Expr. Purif. ج. 25 ع. 2: 305–12. DOI:10.1016/S1046-5928(02)00013-X. PMID:12135564.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
