HSPB2

An Error has occured retrieving Wikidata item for infobox HSPB2‏ (Heat shock protein family B (small) member 2) هوَ بروتين يُشَفر بواسطة جين HSPB2 في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ Suzuki A، Sugiyama Y، Hayashi Y، Nyu-i N، Yoshida M، Nonaka I، Ishiura S، Arahata K، Ohno S (أبريل 1998). "MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase". J Cell Biol. ج. 140 ع. 5: 1113–24. DOI:10.1083/jcb.140.5.1113. PMC:2132705. PMID:9490724.
^ Iwaki A، Nagano T، Nakagawa M، Iwaki T، Fukumaki Y (فبراير 1998). "Identification and characterization of the gene encoding a new member of the alpha-crystallin/small hsp family, closely linked to the alphaB-crystallin gene in a head-to-head manner". Genomics. ج. 45 ع. 2: 386–94. DOI:10.1006/geno.1997.4956. PMID:9344664.
^ "Entrez Gene: HSPB2 heat shock 27kDa protein 2". مؤرشف من الأصل في 2010-12-05.

قراءة متعمقة

Concannon CG، Gorman AM، Samali A (2003). "On the role of Hsp27 in regulating apoptosis". Apoptosis. ج. 8 ع. 1: 61–70. DOI:10.1023/A:1021601103096. PMID:12510153.
Elisei R، Weightman D، Kendall-Taylor P، Vassart G، Ludgate M (1993). "Muscle autoantigens in thyroid associated ophthalmopathy: the limits of molecular genetics". J. Endocrinol. Invest. ج. 16 ع. 7: 533–40. DOI:10.1007/bf03348900. PMID:8227983.
Deak M، Clifton AD، Lucocq LM، Alessi DR (1998). "Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB". EMBO J. ج. 17 ع. 15: 4426–41. DOI:10.1093/emboj/17.15.4426. PMC:1170775. PMID:9687510.
Sugiyama Y، Suzuki A، Kishikawa M، Akutsu R، Hirose T، Waye MM، Tsui SK، Yoshida S، Ohno S (2000). "Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation". J. Biol. Chem. ج. 275 ع. 2: 1095–104. DOI:10.1074/jbc.275.2.1095. PMID:10625651.
Baysal BE، Willett-Brozick JE، Taschner PE، Dauwerse JG، Devilee P، Devlin B (2001). "A high-resolution integrated map spanning the SDHD gene at 11q23: a 1.1-Mb BAC contig, a partial transcript map and 15 new repeat polymorphisms in a tumour-suppressor region". Eur. J. Hum. Genet. ج. 9 ع. 2: 121–9. DOI:10.1038/sj.ejhg.5200585. PMID:11313745.
Nakagawa M، Tsujimoto N، Nakagawa H، Iwaki T، Fukumaki Y، Iwaki A (2001). "Association of HSPB2, a member of the small heat shock protein family, with mitochondria". Exp. Cell Res. ج. 271 ع. 1: 161–8. DOI:10.1006/excr.2001.5362. PMID:11697892.
Ito H، Kamei K، Iwamoto I، Inaguma Y، García-Mata R، Sztul E، Kato K (2002). "Inhibition of proteasomes induces accumulation, phosphorylation, and recruitment of HSP27 and alphaB-crystallin to aggresomes". J. Biochem. ج. 131 ع. 4: 593–603. DOI:10.1093/oxfordjournals.jbchem.a003139. PMID:11926998.
Boxman IL، Kempenaar J، de Haas E، Ponec M (2003). "Induction of HSP27 nuclear immunoreactivity during stress is modulated by vitamin C.". Exp. Dermatol. ج. 11 ع. 6: 509–17. DOI:10.1034/j.1600-0625.2002.110603.x. PMID:12473058.
Patel VM، Heinel LA، Provencio JJ، Vinall PE، Kramer MS، Rosenwasser RH (2003). "Validation of image analysis for enzyme histochemical and immunocytochemical staining". Biotechnic & Histochemistry. ج. 77 ع. 4: 213–21. DOI:10.1080/714028196. PMID:12503731.
Mao H، Li F، Ruchalski K، Mosser DD، Schwartz JH، Wang Y، Borkan SC (2003). "hsp72 inhibits focal adhesion kinase degradation in ATP-depleted renal epithelial cells". J. Biol. Chem. ج. 278 ع. 20: 18214–20. DOI:10.1074/jbc.M300126200. PMID:12611892.
Yonekura N، Yokota S، Yonekura K، Dehari H، Arata S، Kohama G، Fujii N (2003). "Interferon-gamma downregulates Hsp27 expression and suppresses the negative regulation of cell death in oral squamous cell carcinoma lines". Cell Death Differ. ج. 10 ع. 3: 313–22. DOI:10.1038/sj.cdd.4401169. PMID:12700631.
Kantham L، Kerr-Bayles L، Godde N، Quick M، Webb R، Sunderland T، Bond J، Walder K، Augert G، Collier G (2003). "Beacon interacts with cdc2/cdc28-like kinases". Biochem. Biophys. Res. Commun. ج. 304 ع. 1: 125–9. DOI:10.1016/S0006-291X(03)00549-7. PMID:12705895.
Yaglom J، O'Callaghan-Sunol C، Gabai V، Sherman MY (2003). "Inactivation of dual-specificity phosphatases is involved in the regulation of extracellular signal-regulated kinases by heat shock and hsp72". Mol. Cell. Biol. ج. 23 ع. 11: 3813–24. DOI:10.1128/MCB.23.11.3813-3824.2003. PMC:155207. PMID:12748284.
Park KJ، Gaynor RB، Kwak YT (2003). "Heat shock protein 27 association with the I kappa B kinase complex regulates tumor necrosis factor alpha-induced NF-kappa B activation". J. Biol. Chem. ج. 278 ع. 37: 35272–8. DOI:10.1074/jbc.M305095200. PMID:12829720.
Wen FC، Li YH، Tsai HF، Lin CH، Li C، Liu CS، Lii CK، Nukina N، Hsieh M (2003). "Down-regulation of heat shock protein 27 in neuronal cells and non-neuronal cells expressing mutant ataxin-3". FEBS Lett. ج. 546 ع. 2–3: 307–14. DOI:10.1016/S0014-5793(03)00605-7. PMID:12832059.
Parcellier A، Schmitt E، Gurbuxani S، Seigneurin-Berny D، Pance A، Chantôme A، Plenchette S، Khochbin S، Solary E، Garrido C (2003). "HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation". Mol. Cell. Biol. ج. 23 ع. 16: 5790–802. DOI:10.1128/MCB.23.16.5790-5802.2003. PMC:166315. PMID:12897149.

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

[pmid9490724-1] Suzuki A، Sugiyama Y، Hayashi Y، Nyu-i N، Yoshida M، Nonaka I، Ishiura S، Arahata K، Ohno S (أبريل 1998). "MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase". J Cell Biol. ج. 140 ع. 5: 1113–24. DOI:10.1083/jcb.140.5.1113. PMC:2132705. PMID:9490724.

[pmid9344664-2] Iwaki A، Nagano T، Nakagawa M، Iwaki T، Fukumaki Y (فبراير 1998). "Identification and characterization of the gene encoding a new member of the alpha-crystallin/small hsp family, closely linked to the alphaB-crystallin gene in a head-to-head manner". Genomics. ج. 45 ع. 2: 386–94. DOI:10.1006/geno.1997.4956. PMID:9344664.

[entrez-3] "Entrez Gene: HSPB2 heat shock 27kDa protein 2". مؤرشف من الأصل في 2010-12-05.

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