CKAP5

An Error has occured retrieving Wikidata item for infobox CKAP5‏ (Cytoskeleton associated protein 5) هوَ بروتين يُشَفر بواسطة جين CKAP5 في الإنسان.^[1]^[2]^[3]^[4]^[5]

الوظيفة

الأهمية السريرية

المراجع

^ Cassimeris L، Morabito J (2004). "TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly". Mol. Biol. Cell. ج. 15 ع. 4: 1580–90. DOI:10.1091/mbc.E03-07-0544. PMC:379257. PMID:14718566.
^ Nagase T، Miyajima N، Tanaka A، Sazuka T، Seki N، Sato S، Tabata S، Ishikawa K، Kawarabayasi Y، Kotani H (يوليو 1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. ج. 2 ع. 1: 37–43. DOI:10.1093/dnares/2.1.37. PMID:7788527.
^ "Entrez Gene: CKAP5 cytoskeleton associated protein 5". مؤرشف من الأصل في 2010-12-05.
^ Barr AR، Gergely F (2008). "MCAK-independent functions of ch-Tog/XMAP215 in microtubule plus-end dynamics". Mol. Cell. Biol. ج. 28 ع. 23: 7199–211. DOI:10.1128/MCB.01040-08. PMC:2593372. PMID:18809577.
^ Charrasse S، Mazel M، Taviaux S، Berta P، Chow T، Larroque C (فبراير 1996). "Characterization of the cDNA and pattern of expression of a new gene over-expressed in human hepatomas and colonic tumors". Eur. J. Biochem. ج. 234 ع. 2: 406–13. DOI:10.1111/j.1432-1033.1995.406_b.x. PMID:8536682.

قراءة متعمقة

Basto R، Gergely F، Draviam VM، Ohkura H، Liley K، Raff JW (2007). "Hsp90 is required to localise cyclin B and Msps/ch-TOG to the mitotic spindle in Drosophila and humans". J. Cell Sci. ج. 120 ع. Pt 7: 1278–87. DOI:10.1242/jcs.000604. PMID:17376965.
Kosturko LD، Maggipinto MJ، D'Sa C، Carson JH، Barbarese E (2005). "The microtubule-associated protein tumor overexpressed gene binds to the RNA trafficking protein heterogeneous nuclear ribonucleoprotein A2". Mol. Biol. Cell. ج. 16 ع. 4: 1938–47. DOI:10.1091/mbc.E04-08-0709. PMC:1073673. PMID:15703215.
Beausoleil SA، Jedrychowski M، Schwartz D، Elias JE، Villén J، Li J، Cohn MA، Cantley LC، Gygi SP (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. ج. 101 ع. 33: 12130–5. DOI:10.1073/pnas.0404720101. PMC:514446. PMID:15302935.
Cassimeris L، Morabito J (2004). "TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly". Mol. Biol. Cell. ج. 15 ع. 4: 1580–90. DOI:10.1091/mbc.E03-07-0544. PMC:379257. PMID:14718566.
Conte N، Delaval B، Ginestier C، Ferrand A، Isnardon D، Larroque C، Prigent C، Séraphin B، Jacquemier J، Birnbaum D (2003). "TACC1-chTOG-Aurora A protein complex in breast cancer". Oncogene. ج. 22 ع. 50: 8102–16. DOI:10.1038/sj.onc.1206972. PMID:14603251.
Gergely F، Draviam VM، Raff JW (2003). "The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells". Genes Dev. ج. 17 ع. 3: 336–41. DOI:10.1101/gad.245603. PMC:195983. PMID:12569123.
Nakayama M، Kikuno R، Ohara O (2002). "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs". Genome Res. ج. 12 ع. 11: 1773–84. DOI:10.1101/gr.406902. PMC:187542. PMID:12421765.
Lauffart B، Howell SJ، Tasch JE، Cowell JK، Still IH (2002). "Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells". Biochem. J. ج. 363 ع. Pt 1: 195–200. DOI:10.1042/0264-6021:3630195. PMC:1222467. PMID:11903063.
Bonaldo MF، Lennon G، Soares MB (1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. ج. 6 ع. 9: 791–806. DOI:10.1101/gr.6.9.791. PMID:8889548.
Nakamura S، Grigoriev I، Nogi T، Hamaji T، Cassimeris L، Mimori-Kiyosue Y (2012). "Dissecting the nanoscale distributions and functions of microtubule-end-binding proteins EB1 and ch-TOG in interphase HeLa cells". PLoS ONE. ج. 7 ع. 12: e51442. DOI:10.1371/journal.pone.0051442. PMC:3520847. PMID:23251535.
Zanic M، Widlund PO، Hyman AA، Howard J (2013). "Synergy between XMAP215 and EB1 increases microtubule growth rates to physiological levels". Nat. Cell Biol. ج. 15 ع. 6: 688–93. DOI:10.1038/ncb2744. PMID:23666085.

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

[1] Cassimeris L، Morabito J (2004). "TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly". Mol. Biol. Cell. ج. 15 ع. 4: 1580–90. DOI:10.1091/mbc.E03-07-0544. PMC:379257. PMID:14718566.

[pmid7788527-2] Nagase T، Miyajima N، Tanaka A، Sazuka T، Seki N، Sato S، Tabata S، Ishikawa K، Kawarabayasi Y، Kotani H (يوليو 1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. ج. 2 ع. 1: 37–43. DOI:10.1093/dnares/2.1.37. PMID:7788527.

[entrez-3] "Entrez Gene: CKAP5 cytoskeleton associated protein 5". مؤرشف من الأصل في 2010-12-05.

[4] Barr AR، Gergely F (2008). "MCAK-independent functions of ch-Tog/XMAP215 in microtubule plus-end dynamics". Mol. Cell. Biol. ج. 28 ع. 23: 7199–211. DOI:10.1128/MCB.01040-08. PMC:2593372. PMID:18809577.

[pmid8536682-5] Charrasse S، Mazel M، Taviaux S، Berta P، Chow T، Larroque C (فبراير 1996). "Characterization of the cDNA and pattern of expression of a new gene over-expressed in human hepatomas and colonic tumors". Eur. J. Biochem. ج. 234 ع. 2: 406–13. DOI:10.1111/j.1432-1033.1995.406_b.x. PMID:8536682.

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