LMO1

An Error has occured retrieving Wikidata item for infobox LMO1‏ (LIM domain only 1) هوَ بروتين يُشَفر بواسطة جين LMO1 في الإنسان.^[1]^[2]^[1]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ ^أ ^ب "Entrez Gene: LMO1 LIM domain only 1 (rhombotin 1)". مؤرشف من الأصل في 2010-12-05.
^ McGuire EA، Davis AR، Korsmeyer SJ (مارس 1991). "T-cell translocation gene 1 (Ttg-1) encodes a nuclear protein normally expressed in neural lineage cells". Blood. ج. 77 ع. 3: 599–606. PMID:1703797.
^ Boehm T، Foroni L، Kaneko Y، Perutz MF، Rabbitts TH (يونيو 1991). "The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13". Proc Natl Acad Sci U S A. ج. 88 ع. 10: 4367–71. Bibcode:1991PNAS...88.4367B. DOI:10.1073/pnas.88.10.4367. PMC:51660. PMID:2034676.

قراءة متعمقة

Foroni L، Boehm T، White L، وآخرون (1992). "The rhombotin gene family encode related LIM-domain proteins whose differing expression suggests multiple roles in mouse development". J. Mol. Biol. ج. 226 ع. 3: 747–61. DOI:10.1016/0022-2836(92)90630-3. PMID:1507224.
Boehm T، Spillantini MG، Sofroniew MV، وآخرون (1991). "Developmentally regulated and tissue specific expression of mRNAs encoding the two alternative forms of the LIM domain oncogene rhombotin: evidence for thymus expression". Oncogene. ج. 6 ع. 5: 695–703. PMID:2052354.
Chen Q، Cheng JT، Tasi LH، وآخرون (1990). "The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein". EMBO J. ج. 9 ع. 2: 415–24. PMC:551682. PMID:2303035.
Boehm T، Greenberg JM، Buluwela L، وآخرون (1990). "An unusual structure of a putative T cell oncogene which allows production of similar proteins from distinct mRNAs". EMBO J. ج. 9 ع. 3: 857–68. PMC:551746. PMID:2311586.
McGuire EA، Hockett RD، Pollock KM، وآخرون (1989). "The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein". Mol. Cell. Biol. ج. 9 ع. 5: 2124–32. PMC:363006. PMID:2501659.
Boehm T، Baer R، Lavenir I، وآخرون (1988). "The mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15". EMBO J. ج. 7 ع. 2: 385–94. PMC:454331. PMID:3259177.
Wadman I، Li J، Bash RO، وآخرون (1994). "Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia". EMBO J. ج. 13 ع. 20: 4831–9. PMC:395422. PMID:7957052.
Valge-Archer VE، Osada H، Warren AJ، وآخرون (1994). "The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells". Proc. Natl. Acad. Sci. U.S.A. ج. 91 ع. 18: 8617–21. Bibcode:1994PNAS...91.8617V. DOI:10.1073/pnas.91.18.8617. PMC:44657. PMID:8078932.
Arber S، Caroni P (1996). "Specificity of single LIM motifs in targeting and LIM/LIM interactions in situ". Genes Dev. ج. 10 ع. 3: 289–300. DOI:10.1101/gad.10.3.289. PMID:8595880.
Jurata LW، Kenny DA، Gill GN (1996). "Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development". Proc. Natl. Acad. Sci. U.S.A. ج. 93 ع. 21: 11693–8. Bibcode:1996PNAS...9311693J. DOI:10.1073/pnas.93.21.11693. PMC:38120. PMID:8876198.
Ono Y، Fukuhara N، Yoshie O (1997). "Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL". J. Biol. Chem. ج. 272 ع. 7: 4576–81. DOI:10.1074/jbc.272.7.4576. PMID:9020185.
Valge-Archer V، Forster A، Rabbitts TH (1999). "The LMO1 and LDB1 proteins interact in human T cell acute leukaemia with the chromosomal translocation t(11;14)(p15;q11)". Oncogene. ج. 17 ع. 24: 3199–202. DOI:10.1038/sj.onc.1202353. PMID:9872335.
Bao J، Talmage DA، Role LW، Gautier J (2000). "Regulation of neurogenesis by interactions between HEN1 and neuronal LMO proteins". Development. ج. 127 ع. 2: 425–35. PMID:10603358.
Cichutek A، Brueckmann T، Seipel B، وآخرون (2001). "Comparative architectural aspects of regions of conserved synteny on human chromosome 11p15.3 and mouse chromosome 7 (including genes WEE1 and LMO1)". Cytogenet. Cell Genet. ج. 93 ع. 3–4: 277–83. DOI:10.1159/000056998. PMID:11528126.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
Lin YW، Deveney R، Barbara M، وآخرون (2005). "OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1". Cancer Res. ج. 65 ع. 16: 7151–8. DOI:10.1158/0008-5472.CAN-05-1400. PMC:1681523. PMID:16103065.
Saeki N، Kim DH، Usui T، وآخرون (2007). "GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling". Oncogene. ج. 26 ع. 45: 6488–98. DOI:10.1038/sj.onc.1210475. PMID:17471240.

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

[entrez-1] أ ^ب "Entrez Gene: LMO1 LIM domain only 1 (rhombotin 1)". مؤرشف من الأصل في 2010-12-05.

[pmid1703797-2] McGuire EA، Davis AR، Korsmeyer SJ (مارس 1991). "T-cell translocation gene 1 (Ttg-1) encodes a nuclear protein normally expressed in neural lineage cells". Blood. ج. 77 ع. 3: 599–606. PMID:1703797.

[pmid2034676-3] Boehm T، Foroni L، Kaneko Y، Perutz MF، Rabbitts TH (يونيو 1991). "The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13". Proc Natl Acad Sci U S A. ج. 88 ع. 10: 4367–71. Bibcode:1991PNAS...88.4367B. DOI:10.1073/pnas.88.10.4367. PMC:51660. PMID:2034676.

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