HAPLN1

An Error has occured retrieving Wikidata item for infobox HAPLN1‏ (Hyaluronan and proteoglycan link protein 1) هوَ بروتين يُشَفر بواسطة جين HAPLN1 في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ "Entrez Gene: HAPLN1 hyaluronan and proteoglycan link protein 1". مؤرشف من الأصل في 2010-12-05.
^ Dudhia J، Hardingham TE (مايو 1990). "The primary structure of human cartilage link protein". Nucleic Acids Res. ج. 18 ع. 5: 1292. DOI:10.1093/nar/18.5.1292. PMC:330454. PMID:2320422.
^ Osborne-Lawrence SL، Sinclair AK، Hicks RC، Lacey SW، Eddy RL Jr، Byers MG، Shows TB، Duby AD (مارس 1991). "Complete amino acid sequence of human cartilage link protein (CRTL1) deduced from cDNA clones and chromosomal assignment of the gene". Genomics. ج. 8 ع. 3: 562–7. DOI:10.1016/0888-7543(90)90044-U. PMID:2286376.

قراءة متعمقة

Mundlos S، Meyer R، Yamada Y، Zabel B (1992). "Distribution of cartilage proteoglycan (aggrecan) core protein and link protein gene expression during human skeletal development". Matrix. ج. 11 ع. 5: 339–46. DOI:10.1016/s0934-8832(11)80205-2. PMID:1725805.
Rhodes C، Savagner P، Line S، وآخرون (1991). "Characterization of the promoter for the rat and human link protein gene". Nucleic Acids Res. ج. 19 ع. 8: 1933–9. DOI:10.1093/nar/19.8.1933. PMC:328126. PMID:2030970.
Dudhia J، Hardingham TE (1990). "The primary structure of human cartilage link protein". Nucleic Acids Res. ج. 18 ع. 8: 2214. DOI:10.1093/nar/18.8.2214. PMC:330736. PMID:2336413.
Perkins SJ، Nealis AS، Dudhia J، Hardingham TE (1989). "Immunoglobulin fold and tandem repeat structures in proteoglycan N-terminal domains and link protein". J. Mol. Biol. ج. 206 ع. 4: 737–53. DOI:10.1016/0022-2836(89)90580-9. PMID:2738916.
Nguyen Q، Murphy G، Hughes CE، وآخرون (1993). "Matrix metalloproteinases cleave at two distinct sites on human cartilage link protein". Biochem. J. 295. ( Pt 2): 595–8. PMC:1134922. PMID:7694569.
Dudhia J، Bayliss MT، Hardingham TE (1994). "Human link protein gene: structure and transcription pattern in chondrocytes". Biochem. J. 303. ( Pt 1): 329–33. PMC:1137594. PMID:7945259.
Guerassimov A، Zhang Y، Banerjee S، وآخرون (1998). "Autoimmunity to cartilage link protein in patients with rheumatoid arthritis and ankylosing spondylitis". J. Rheumatol. ج. 25 ع. 8: 1480–4. PMID:9712087.
Perveen R، Hart-Holden N، Dixon MJ، وآخرون (1999). "Refined genetic and physical localization of the Wagner disease (WGN1) locus and the genes CRTL1 and CSPG2 to a 2- to 2.5-cM region of chromosome 5q14.3". Genomics. ج. 57 ع. 2: 219–26. DOI:10.1006/geno.1999.5766. PMID:10198161.
Hirakawa S، Oohashi T، Su WD، وآخرون (2000). "The brain link protein-1 (BRAL1): cDNA cloning, genomic structure, and characterization as a novel link protein expressed in adult brain". Biochem. Biophys. Res. Commun. ج. 276 ع. 3: 982–9. DOI:10.1006/bbrc.2000.3583. PMID:11027579.
Pokharna HK، Pottenger LA (2000). "Glycation induced crosslinking of link proteins, in vivo and in vitro". J. Surg. Res. ج. 94 ع. 1: 35–42. DOI:10.1006/jsre.2000.6000. PMID:11038300.
Milz S، Schlüter T، Putz R، وآخرون (2001). "Fibrocartilage in the transverse ligament of the human atlas". Spine. ج. 26 ع. 16: 1765–71. DOI:10.1097/00007632-200108150-00007. PMID:11493848.
Sun GW، Kobayashi H، Suzuki M، وآخرون (2003). "Production of cartilage link protein by human granulosa-lutein cells". J. Endocrinol. ج. 175 ع. 2: 505–15. DOI:10.1677/joe.0.1750505. PMID:12429048.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Spicer AP، Joo A، Bowling RA (2003). "A hyaluronan binding link protein gene family whose members are physically linked adjacent to chondroitin sulfate proteoglycan core protein genes: the missing links". J. Biol. Chem. ج. 278 ع. 23: 21083–91. DOI:10.1074/jbc.M213100200. PMID:12663660.
Matsumoto K، Shionyu M، Go M، وآخرون (2003). "Distinct interaction of versican/PG-M with hyaluronan and link protein". J. Biol. Chem. ج. 278 ع. 42: 41205–12. DOI:10.1074/jbc.M305060200. PMID:12888576.
Shi S، Grothe S، Zhang Y، وآخرون (2004). "Link protein has greater affinity for versican than aggrecan". J. Biol. Chem. ج. 279 ع. 13: 12060–6. DOI:10.1074/jbc.M310091200. PMID:14724283.
Kou I، Ikegawa S (2005). "SOX9-dependent and -independent transcriptional regulation of human cartilage link protein". J. Biol. Chem. ج. 279 ع. 49: 50942–8. DOI:10.1074/jbc.M406786200. PMID:15456769.
Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.

هذه بذرة مقالة عن جين على كروموسوم 5 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[entrez-1] "Entrez Gene: HAPLN1 hyaluronan and proteoglycan link protein 1". مؤرشف من الأصل في 2010-12-05.

[pmid2320422-2] Dudhia J، Hardingham TE (مايو 1990). "The primary structure of human cartilage link protein". Nucleic Acids Res. ج. 18 ع. 5: 1292. DOI:10.1093/nar/18.5.1292. PMC:330454. PMID:2320422.

[pmid2286376-3] Osborne-Lawrence SL، Sinclair AK، Hicks RC، Lacey SW، Eddy RL Jr، Byers MG، Shows TB، Duby AD (مارس 1991). "Complete amino acid sequence of human cartilage link protein (CRTL1) deduced from cDNA clones and chromosomal assignment of the gene". Genomics. ج. 8 ع. 3: 562–7. DOI:10.1016/0888-7543(90)90044-U. PMID:2286376.

[1]

[2]

[3]