SLC6A6

An Error has occured retrieving Wikidata item for infobox SLC6A6‏ (Solute carrier family 6 member 6) هوَ بروتين يُشَفر بواسطة جين SLC6A6 في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ Jhiang SM، Fithian L، Smanik P، McGill J، Tong Q، Mazzaferri EL (مارس 1993). "Cloning of the human taurine transporter and characterization of taurine uptake in thyroid cells". FEBS Lett. ج. 318 ع. 2: 139–44. DOI:10.1016/0014-5793(93)80008-I. PMID:8382624.
^ "Entrez Gene: SLC6A6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6". مؤرشف من الأصل في 2010-12-05.
^ Ramamoorthy S، Leibach FH، Mahesh VB، Han H، Yang-Feng T، Blakely RD، Ganapathy V (يوليو 1994). "Functional characterization and chromosomal localization of a cloned taurine transporter from human placenta". Biochem J. ج. 300 ع. 3: 893–900. PMC:1138249. PMID:8010975.

قراءة متعمقة

Uchida S، Kwon HM، Yamauchi A، وآخرون (1992). "Molecular cloning of the cDNA for an MDCK cell Na(+)- and Cl(−)-dependent taurine transporter that is regulated by hypertonicity". Proc. Natl. Acad. Sci. U.S.A. ج. 89 ع. 17: 8230–4. DOI:10.1073/pnas.89.17.8230. PMC:49891. PMID:1518851.
Miyamoto Y، Liou GI، Sprinkle TJ (1996). "Isolation of a cDNA encoding a taurine transporter in the human retinal pigment epithelium". Curr. Eye Res. ج. 15 ع. 3: 345–9. DOI:10.3109/02713689609007631. PMID:8654117.
Bonaldo MF، Lennon G، Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. ج. 6 ع. 9: 791–806. DOI:10.1101/gr.6.9.791. PMID:8889548.
Mochizuki T، Satsu H، Shimizu M (2002). "Tumor necrosis factor alpha stimulates taurine uptake and transporter gene expression in human intestinal Caco-2 cells". FEBS Lett. ج. 517 ع. 1–3: 92–6. DOI:10.1016/S0014-5793(02)02584-X. PMID:12062416.
Han X، Patters AB، Chesney RW (2002). "Transcriptional repression of taurine transporter gene (TauT) by p53 in renal cells". J. Biol. Chem. ج. 277 ع. 42: 39266–73. DOI:10.1074/jbc.M205939200. PMID:12163498.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Han X، Chesney RW (2003). "Regulation of taurine transporter gene (TauT) by WT1". FEBS Lett. ج. 540 ع. 1–3: 71–6. DOI:10.1016/S0014-5793(03)00227-8. PMID:12681485.
Roos S، Powell TL، Jansson T (2004). "Human placental taurine transporter in uncomplicated and IUGR pregnancies: cellular localization, protein expression, and regulation". Am. J. Physiol. Regul. Integr. Comp. Physiol. ج. 287 ع. 4: R886–93. DOI:10.1152/ajpregu.00232.2004. PMID:15166008.
Satsu H، Manabe M، Shimizu M (2004). "Activation of Ca2+/calmodulin-dependent protein kinase II is involved in hyperosmotic induction of the human taurine transporter". FEBS Lett. ج. 569 ع. 1–3: 123–8. DOI:10.1016/j.febslet.2004.05.062. PMID:15225620.
Mochizuki T، Satsu H، Nakano T، Shimizu M (2005). "Regulation of the human taurine transporter by TNF-alpha and an anti-inflammatory function of taurine in human intestinal Caco-2 cells". BioFactors. ج. 21 ع. 1–4: 141–4. DOI:10.1002/biof.552210128. PMID:15630186.
Mochizuki T، Satsu H، Shimizu M (2005). "Signaling pathways involved in tumor necrosis factor alpha-induced upregulation of the taurine transporter in Caco-2 cells". FEBS Lett. ج. 579 ع. 14: 3069–74. DOI:10.1016/j.febslet.2005.04.063. PMID:15907840.
Nakashima E، Pop-Busui R، Towns R، وآخرون (2006). "Regulation of the human taurine transporter by oxidative stress in retinal pigment epithelial cells stably transformed to overexpress aldose reductase". Antioxid. Redox Signal. ج. 7 ع. 11–12: 1530–42. DOI:10.1089/ars.2005.7.1530. PMID:16356117.
Iruloh CG، D'Souza SW، Speake PF، وآخرون (2007). "Taurine transporter in fetal T lymphocytes and platelets: differential expression and functional activity". Am. J. Physiol., Cell Physiol. ج. 292 ع. 1: C332–41. DOI:10.1152/ajpcell.00634.2005. PMID:16956961.

هذه بذرة مقالة عن جين على كروموسوم 3 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[pmid8382624-1] Jhiang SM، Fithian L، Smanik P، McGill J، Tong Q، Mazzaferri EL (مارس 1993). "Cloning of the human taurine transporter and characterization of taurine uptake in thyroid cells". FEBS Lett. ج. 318 ع. 2: 139–44. DOI:10.1016/0014-5793(93)80008-I. PMID:8382624.

[entrez-2] "Entrez Gene: SLC6A6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6". مؤرشف من الأصل في 2010-12-05.

[pmid8010975-3] Ramamoorthy S، Leibach FH، Mahesh VB، Han H، Yang-Feng T، Blakely RD، Ganapathy V (يوليو 1994). "Functional characterization and chromosomal localization of a cloned taurine transporter from human placenta". Biochem J. ج. 300 ع. 3: 893–900. PMC:1138249. PMID:8010975.

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