HCLS1

An Error has occured retrieving Wikidata item for infobox HCLS1‏ (Hematopoietic cell-specific Lyn substrate 1) هوَ بروتين يُشَفر بواسطة جين HCLS1 في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ Egashira M، Kitamura D، Watanabe T، Niikawa N (يناير 1997). "The human HCLS1 gene maps to chromosome 3q13 by fluorescence in situ hybridization". Cytogenet Cell Genet. ج. 72 ع. 2–3: 175–6. DOI:10.1159/000134179. PMID:8978766.
^ "Entrez Gene: HCLS1 hematopoietic cell-specific Lyn substrate 1". مؤرشف من الأصل في 2010-12-05.
^ van Rossum AG، Schuuring-Scholtes E، van Buuren-van Seggelen V، Kluin PM، Schuuring E (مارس 2005). "Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain". BMC Genomics. ج. 6: 15. DOI:10.1186/1471-2164-6-15. PMC:554100. PMID:15710041.

قراءة متعمقة

Kitamura D، Kaneko H، Miyagoe Y، وآخرون (1990). "Isolation and characterization of a novel human gene expressed specifically in the cells of hematopoietic lineage". Nucleic Acids Res. ج. 17 ع. 22: 9367–79. PMC:335138. PMID:2587259.
Yamanashi Y، Okada M، Semba T، وآخرون (1993). "Identification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling". Proc. Natl. Acad. Sci. U.S.A. ج. 90 ع. 8: 3631–5. Bibcode:1993PNAS...90.3631Y. DOI:10.1073/pnas.90.8.3631. PMC:46355. PMID:7682714.
Hata D، Nakamura T، Kawakami T، وآخرون (1994). "Tyrosine phosphorylation of MB-1, B29, and HS1 proteins in human B cells following receptor crosslinking". Immunol. Lett. ج. 40 ع. 1: 65–71. DOI:10.1016/0165-2478(94)90208-9. PMID:7927516.
Maruyama K، Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. ج. 138 ع. 1–2: 171–4. DOI:10.1016/0378-1119(94)90802-8. PMID:8125298.
Egerton M، Moritz RL، Druker B، وآخرون (1996). "Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes". Biochem. Biophys. Res. Commun. ج. 224 ع. 3: 666–74. DOI:10.1006/bbrc.1996.1082. PMID:8713105.
Suzuki Y، Demoliere C، Kitamura D، وآخرون (1997). "HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases". J. Immunol. ج. 158 ع. 6: 2736–44. PMID:9058808.
Yamanashi Y، Fukuda T، Nishizumi H، وآخرون (1997). "Role of tyrosine phosphorylation of HS1 in B cell antigen receptor-mediated apoptosis". J. Exp. Med. ج. 185 ع. 7: 1387–92. DOI:10.1084/jem.185.7.1387. PMC:2196252. PMID:9104825.
Suzuki Y، Yoshitomo-Nakagawa K، Maruyama K، وآخرون (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. ج. 200 ع. 1–2: 149–56. DOI:10.1016/S0378-1119(97)00411-3. PMID:9373149.
Brunati AM، Donella-Deana A، James P، وآخرون (1999). "Molecular features underlying the sequential phosphorylation of HS1 protein and its association with c-Fgr protein-tyrosine kinase". J. Biol. Chem. ج. 274 ع. 11: 7557–64. DOI:10.1074/jbc.274.11.7557. PMID:10066823.
Nagata Y، Kiefer F، Watanabe T، Todokoro K (1999). "Activation of hematopoietic progenitor kinase-1 by erythropoietin". Blood. ج. 93 ع. 10: 3347–54. PMID:10233887.
Takemoto Y، Furuta M، Sato M، وآخرون (2000). "Isolation and characterization of a novel HS1 SH3 domain binding protein, HS1BP3". Int. Immunol. ج. 11 ع. 12: 1957–64. DOI:10.1093/intimm/11.12.1957. PMID:10590261.
Ruzzene M، Brunati AM، Sarno S، وآخرون (2000). "Ser/Thr phosphorylation of hematopoietic specific protein 1 (HS1): implication of protein kinase CK2". Eur. J. Biochem. ج. 267 ع. 10: 3065–72. DOI:10.1046/j.1432-1033.2000.01333.x. PMID:10806407.
Chen YR، Kori R، John B، Tan TH (2001). "Caspase-mediated cleavage of actin-binding and SH3-domain-containing proteins cortactin, HS1, and HIP-55 during apoptosis". Biochem. Biophys. Res. Commun. ج. 288 ع. 4: 981–9. DOI:10.1006/bbrc.2001.5862. PMID:11689006.
Ruzzene M، Penzo D، Pinna LA (2002). "Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells". Biochem. J. ج. 364 ع. Pt 1: 41–7. DOI:10.1042/bj3640041. PMC:1222543. PMID:11988074.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Salomon AR، Ficarro SB، Brill LM، وآخرون (2003). "Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry". Proc. Natl. Acad. Sci. U.S.A. ج. 100 ع. 2: 443–8. Bibcode:2003PNAS..100..443S. DOI:10.1073/pnas.2436191100. PMC:141014. PMID:12522270.
Uruno T، Zhang P، Liu J، وآخرون (2003). "Haematopoietic lineage cell-specific protein 1 (HS1) promotes actin-related protein (Arp) 2/3 complex-mediated actin polymerization". Biochem. J. ج. 371 ع. Pt 2: 485–93. DOI:10.1042/BJ20021791. PMC:1223309. PMID:12534372.
Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
Brill LM، Salomon AR، Ficarro SB، وآخرون (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. ج. 76 ع. 10: 2763–72. DOI:10.1021/ac035352d. PMID:15144186.

هذه بذرة مقالة عن جين على كروموسوم 3 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[pmid8978766-1] Egashira M، Kitamura D، Watanabe T، Niikawa N (يناير 1997). "The human HCLS1 gene maps to chromosome 3q13 by fluorescence in situ hybridization". Cytogenet Cell Genet. ج. 72 ع. 2–3: 175–6. DOI:10.1159/000134179. PMID:8978766.

[entrez-2] "Entrez Gene: HCLS1 hematopoietic cell-specific Lyn substrate 1". مؤرشف من الأصل في 2010-12-05.

[pmid15710041-3] van Rossum AG، Schuuring-Scholtes E، van Buuren-van Seggelen V، Kluin PM، Schuuring E (مارس 2005). "Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain". BMC Genomics. ج. 6: 15. DOI:10.1186/1471-2164-6-15. PMC:554100. PMID:15710041.

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