Giantin

An Error has occured retrieving Wikidata item for infobox Giantin‏ (Golgin B1) هوَ بروتين يُشَفر بواسطة جين Giantin في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ "Entrez Gene: GOLGB1 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1". مؤرشف من الأصل في 2010-12-05.
^ Oka T، Ungar D، Hughson FM، Krieger M (أبريل 2004). "The COG and COPI complexes interact to control the abundance of GEARs, a subset of Golgi integral membrane proteins". Mol Biol Cell. ج. 15 ع. 5: 2423–35. DOI:10.1091/mbc.E03-09-0699. PMC:404034. PMID:15004235.
^ Linstedt AD، Hauri HP (نوفمبر 1993). "Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa". Mol Biol Cell. ج. 4 ع. 7: 679–93. DOI:10.1091/mbc.4.7.679. PMC:300978. PMID:7691276.

قراءة متعمقة

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Seelig HP، Schranz P، Schröter H، وآخرون (1994). "Macrogolgin--a new 376 kD Golgi complex outer membrane protein as target of antibodies in patients with rheumatic diseases and HIV infections". J. Autoimmun. ج. 7 ع. 1: 67–91. DOI:10.1006/jaut.1994.1006. PMID:8198703.
Sönnichsen B، Lowe M، Levine T، وآخرون (1998). "A role for giantin in docking COPI vesicles to Golgi membranes". J. Cell Biol. ج. 140 ع. 5: 1013–21. DOI:10.1083/jcb.140.5.1013. PMC:2132694. PMID:9490716.
Linstedt AD، Jesch SA، Mehta A، وآخرون (2000). "Binding relationships of membrane tethering components. The giantin N terminus and the GM130 N terminus compete for binding to the p115 C terminus". J. Biol. Chem. ج. 275 ع. 14: 10196–201. DOI:10.1074/jbc.275.14.10196. PMID:10744704.
Dirac-Svejstrup AB، Shorter J، Waters MG، Warren G (2000). "Phosphorylation of the vesicle-tethering protein p115 by a casein kinase II-like enzyme is required for Golgi reassembly from isolated mitotic fragments". J. Cell Biol. ج. 150 ع. 3: 475–88. DOI:10.1083/jcb.150.3.475. PMC:2175190. PMID:10931861.
Alvarez C، Garcia-Mata R، Hauri HP، Sztul E (2001). "The p115-interactive proteins GM130 and giantin participate in endoplasmic reticulum-Golgi traffic". J. Biol. Chem. ج. 276 ع. 4: 2693–700. DOI:10.1074/jbc.M007957200. PMID:11035033.
Sohda M، Misumi Y، Yamamoto A، وآخرون (2002). "Identification and characterization of a novel Golgi protein, GCP60, that interacts with the integral membrane protein giantin". J. Biol. Chem. ج. 276 ع. 48: 45298–306. DOI:10.1074/jbc.M108961200. PMID:11590181.
Shorter J، Beard MB، Seemann J، وآخرون (2002). "Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115". J. Cell Biol. ج. 157 ع. 1: 45–62. DOI:10.1083/jcb.200112127. PMC:2173270. PMID:11927603.
Gillingham AK، Pfeifer AC، Munro S (2003). "CASP, the alternatively spliced product of the gene encoding the CCAAT-displacement protein transcription factor, is a Golgi membrane protein related to giantin". Mol. Biol. Cell. ج. 13 ع. 11: 3761–74. DOI:10.1091/mbc.E02-06-0349. PMC:133590. PMID:12429822.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Anderson NL، Polanski M، Pieper R، وآخرون (2004). "The human plasma proteome: a nonredundant list developed by combination of four separate sources". Mol. Cell. Proteomics. ج. 3 ع. 4: 311–26. DOI:10.1074/mcp.M300127-MCP200. PMID:14718574.
Colland F، Jacq X، Trouplin V، وآخرون (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. ج. 14 ع. 7: 1324–32. DOI:10.1101/gr.2334104. PMC:442148. PMID:15231748.
Breuza L، Halbeisen R، Jenö P، وآخرون (2004). "Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46". J. Biol. Chem. ج. 279 ع. 45: 47242–53. DOI:10.1074/jbc.M406644200. PMID:15308636.
Malsam J، Satoh A، Pelletier L، Warren G (2005). "Golgin tethers define subpopulations of COPI vesicles". Science. ج. 307 ع. 5712: 1095–8. DOI:10.1126/science.1108061. PMID:15718469.
Stelzl U، Worm U، Lalowski M، وآخرون (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. ج. 122 ع. 6: 957–68. DOI:10.1016/j.cell.2005.08.029. PMID:16169070.
Rosing M، Ossendorf E، Rak A، Barnekow A (2007). "Giantin interacts with both the small GTPase Rab6 and Rab1". Exp. Cell Res. ج. 313 ع. 11: 2318–25. DOI:10.1016/j.yexcr.2007.03.031. PMID:17475246.

هذه بذرة مقالة عن جين على كروموسوم 3 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[entrez-1] "Entrez Gene: GOLGB1 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1". مؤرشف من الأصل في 2010-12-05.

[pmid15004235-2] Oka T، Ungar D، Hughson FM، Krieger M (أبريل 2004). "The COG and COPI complexes interact to control the abundance of GEARs, a subset of Golgi integral membrane proteins". Mol Biol Cell. ج. 15 ع. 5: 2423–35. DOI:10.1091/mbc.E03-09-0699. PMC:404034. PMID:15004235.

[pmid7691276-3] Linstedt AD، Hauri HP (نوفمبر 1993). "Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa". Mol Biol Cell. ج. 4 ع. 7: 679–93. DOI:10.1091/mbc.4.7.679. PMC:300978. PMID:7691276.

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