CYP8B1

An Error has occured retrieving Wikidata item for infobox CYP8B1‏ (Cytochrome P450 family 8 subfamily B member 1) هوَ بروتين يُشَفر بواسطة جين CYP8B1 في الإنسان.^[1]^[2]

الوظيفة

الأهمية السريرية

المراجع

^ Gåfvels M، Olin M، Chowdhary BP، Raudsepp T، Andersson U، Persson B، Jansson M، Björkhem I، Eggertsen G (مارس 1999). "Structure and chromosomal assignment of the sterol 12alpha-hydroxylase gene (CYP8B1) in human and mouse: eukaryotic cytochrome P-450 gene devoid of introns". Genomics. ج. 56 ع. 2: 184–96. DOI:10.1006/geno.1998.5606. PMID:10051404.
^ "Entrez Gene: CYP8B1". مؤرشف من الأصل في 2009-05-11.

قراءة متعمقة

Li Y، Mezei O، Shay NF (2007). "Human and murine hepatic sterol-12-alpha-hydroxylase and other xenobiotic metabolism mRNA are upregulated by soy isoflavones". J. Nutr. ج. 137 ع. 7: 1705–12. PMID:17585019.
Yang Y، Eggertsen G، Gåffvels M، وآخرون (2004). "Mechanisms of cholesterol and sterol regulatory element binding protein regulation of the sterol 12alpha-hydroxylase gene (CYP8B1)". Biochem. Biophys. Res. Commun. ج. 320 ع. 4: 1204–10. DOI:10.1016/j.bbrc.2004.06.069. PMID:15249218.
Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
Ellis EC (2006). "Suppression of bile acid synthesis by thyroid hormone in primary human hepatocytes". World J. Gastroenterol. ج. 12 ع. 29: 4640–5. PMID:16937432.
Wang J، Greene S، Eriksson LC، وآخرون (2005). "Human sterol 12a-hydroxylase (CYP8B1) is mainly expressed in hepatocytes in a homogenous pattern". Histochem. Cell Biol. ج. 123 ع. 4–5: 441–6. DOI:10.1007/s00418-005-0779-0. PMID:15891895.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Nelson DR، Zeldin DC، Hoffman SM، وآخرون (2004). "Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants". Pharmacogenetics. ج. 14 ع. 1: 1–18. DOI:10.1097/00008571-200401000-00001. PMID:15128046.
Ross CJ، Katzov-Eckert H، Dubé MP، وآخرون (2009). "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy". Nat. Genet. ج. 41 ع. 12: 1345–9. DOI:10.1038/ng.478. PMID:19898482.
Lu Y، Dollé ME، Imholz S، وآخرون (2008). "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations". J. Lipid Res. ج. 49 ع. 12: 2582–9. DOI:10.1194/jlr.M800232-JLR200. PMID:18660489.
Zhang M، Chiang JY (2001). "Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression". J. Biol. Chem. ج. 276 ع. 45: 41690–9. DOI:10.1074/jbc.M105117200. PMID:11535594.

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[pmid10051404-1] Gåfvels M، Olin M، Chowdhary BP، Raudsepp T، Andersson U، Persson B، Jansson M، Björkhem I، Eggertsen G (مارس 1999). "Structure and chromosomal assignment of the sterol 12alpha-hydroxylase gene (CYP8B1) in human and mouse: eukaryotic cytochrome P-450 gene devoid of introns". Genomics. ج. 56 ع. 2: 184–96. DOI:10.1006/geno.1998.5606. PMID:10051404.

[entrez-2] "Entrez Gene: CYP8B1". مؤرشف من الأصل في 2009-05-11.

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