RHOQ

An Error has occured retrieving Wikidata item for infobox RHOQ‏ (Ras homolog family member Q) هوَ بروتين يُشَفر بواسطة جين RHOQ في الإنسان.^[1]^[2]^[3]^[2]

الوظيفة

الأهمية السريرية

المراجع

^ Drivas GT، Shih A، Coutavas E، Rush MG، D'Eustachio P (مايو 1990). "Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line". Mol Cell Biol. ج. 10 ع. 4: 1793–8. PMC:362288. PMID:2108320.
^ ^أ ^ب "Entrez Gene: RHOQ ras homolog gene family, member Q". مؤرشف من الأصل في 2010-12-05.
^ Hoek KS، Schlegel NC، Eichhoff OM، وآخرون (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. ج. 21 ع. 6: 665–76. DOI:10.1111/j.1755-148X.2008.00505.x. PMID:19067971.

قراءة متعمقة

Murphy GA، Solski PA، Jillian SA، وآخرون (1999). "Cellular functions of TC10, a Rho family GTPase: regulation of morphology, signal transduction and cell growth". Oncogene. ج. 18 ع. 26: 3831–45. DOI:10.1038/sj.onc.1202758. PMID:10445846.
Joberty G، Perlungher RR، Macara IG (2000). "The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins". Mol. Cell. Biol. ج. 19 ع. 10: 6585–97. PMC:84628. PMID:10490598.
Joberty G، Petersen C، Gao L، Macara IG (2000). "The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42". Nat. Cell Biol. ج. 2 ع. 8: 531–9. DOI:10.1038/35019573. PMID:10934474.
Vignal E، De Toledo M، Comunale F، وآخرون (2000). "Characterization of TCL, a new GTPase of the rho family related to TC10 andCcdc42". J. Biol. Chem. ج. 275 ع. 46: 36457–64. DOI:10.1074/jbc.M003487200. PMID:10967094.
Michaelson D، Silletti J، Murphy G، وآخرون (2001). "Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding". J. Cell Biol. ج. 152 ع. 1: 111–26. DOI:10.1083/jcb.152.1.111. PMC:2193662. PMID:11149925.
Neudauer CL، Joberty G، Macara IG (2001). "PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10". Biochem. Biophys. Res. Commun. ج. 280 ع. 2: 541–7. DOI:10.1006/bbrc.2000.4160. PMID:11162552.
Chiang SH، Hou JC، Hwang J، وآخرون (2002). "Cloning and functional characterization of related TC10 isoforms, a subfamily of Rho proteins involved in insulin-stimulated glucose transport". J. Biol. Chem. ج. 277 ع. 15: 13067–73. DOI:10.1074/jbc.M109471200. PMID:11821390.
Kanzaki M، Watson RT، Hou JC، وآخرون (2003). "Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes". Mol. Biol. Cell. ج. 13 ع. 7: 2334–46. DOI:10.1091/mbc.01-10-0490. PMC:117317. PMID:12134073.
Chang L، Adams RD، Saltiel AR (2002). "The TC10-interacting protein CIP4/2 is required for insulin-stimulated Glut4 translocation in 3T3L1 adipocytes". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 20: 12835–40. DOI:10.1073/pnas.202495599. PMC:130546. PMID:12242347.
Abe T، Kato M، Miki H، وآخرون (2003). "Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowth". J. Cell Sci. ج. 116 ع. Pt 1: 155–68. DOI:10.1242/jcs.00208. PMID:12456725.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Heilig R، Eckenberg R، Petit JL، وآخرون (2003). "The DNA sequence and analysis of human chromosome 14". Nature. ج. 421 ع. 6923: 601–7. DOI:10.1038/nature01348. PMID:12508121.
Watson RT، Furukawa M، Chiang SH، وآخرون (2003). "The exocytotic trafficking of TC10 occurs through both classical and nonclassical secretory transport pathways in 3T3L1 adipocytes". Mol. Cell. Biol. ج. 23 ع. 3: 961–74. DOI:10.1128/MCB.23.3.961-974.2003. PMC:140699. PMID:12529401.
Inoue M، Chang L، Hwang J، وآخرون (2003). "The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin". Nature. ج. 422 ع. 6932: 629–33. DOI:10.1038/nature01533. PMID:12687004.
Chunqiu Hou J، Pessin JE (2004). "Lipid Raft targeting of the TC10 amino terminal domain is responsible for disruption of adipocyte cortical actin". Mol. Biol. Cell. ج. 14 ع. 9: 3578–91. DOI:10.1091/mbc.E03-01-0012. PMC:196551. PMID:12972548.
Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
Ng Y، Tan I، Lim L، Leung T (2004). "Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding". J. Biol. Chem. ج. 279 ع. 33: 34156–64. DOI:10.1074/jbc.M405252200. PMID:15194684.
Ruusala A، Aspenström P (2004). "Isolation and characterisation of DOCK8, a member of the DOCK180-related regulators of cell morphology". FEBS Lett. ج. 572 ع. 1–3: 159–66. DOI:10.1016/j.febslet.2004.06.095. PMID:15304341.
Nalbant P، Hodgson L، Kraynov V، وآخرون (2004). "Activation of endogenous Cdc42 visualized in living cells". Science. ج. 305 ع. 5690: 1615–9. DOI:10.1126/science.1100367. PMID:15361624.

هذه بذرة مقالة عن جين على كروموسوم 2 بحاجة للتوسيع. فضلًا شارك في تحريرها.

RHOQ في المشاريع الشقيقة:

[pmid2108320-1] Drivas GT، Shih A، Coutavas E، Rush MG، D'Eustachio P (مايو 1990). "Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line". Mol Cell Biol. ج. 10 ع. 4: 1793–8. PMC:362288. PMID:2108320.

[entrez-2] أ ^ب "Entrez Gene: RHOQ ras homolog gene family, member Q". مؤرشف من الأصل في 2010-12-05.

[pmid19067971-3] Hoek KS، Schlegel NC، Eichhoff OM، وآخرون (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. ج. 21 ع. 6: 665–76. DOI:10.1111/j.1755-148X.2008.00505.x. PMID:19067971.

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