BCL2L11

An Error has occured retrieving Wikidata item for infobox BCL2L11‏ (BCL2 like 11) هوَ بروتين يُشَفر بواسطة جين BCL2L11 في الإنسان.^[1]^[2]

الوظيفة

الأهمية السريرية

المراجع

^ O'Connor L، Strasser A، O'Reilly LA، Hausmann G، Adams JM، Cory S، Huang DC (فبراير 1998). "Bim: a novel member of the Bcl-2 family that promotes apoptosis". EMBO J. ج. 17 ع. 2: 384–95. DOI:10.1093/emboj/17.2.384. PMC:1170389. PMID:9430630.
^ Hsu SY، Lin P، Hsueh AJ (نوفمبر 1998). "BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members". Mol Endocrinol. ج. 12 ع. 9: 1432–40. DOI:10.1210/mend.12.9.0166. PMID:9731710.

قراءة متعمقة

Wang K، Yin XM، Chao DT، وآخرون (1996). "BID: a novel BH3 domain-only death agonist". Genes Dev. ج. 10 ع. 22: 2859–69. DOI:10.1101/gad.10.22.2859. PMID:8918887.
Zha J، Harada H، Yang E، وآخرون (1997). "Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)". Cell. ج. 87 ع. 4: 619–28. DOI:10.1016/S0092-8674(00)81382-3. PMID:8929531.
Huang DC، Adams JM، Cory S (1998). "The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4". EMBO J. ج. 17 ع. 4: 1029–39. DOI:10.1093/emboj/17.4.1029. PMC:1170452. PMID:9463381.
Puthalakath H، Huang DC، O'Reilly LA، وآخرون (1999). "The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex". Mol. Cell. ج. 3 ع. 3: 287–96. DOI:10.1016/S1097-2765(00)80456-6. PMID:10198631.
Ohi N، Tokunaga A، Tsunoda H، وآخرون (1999). "A novel adenovirus E1B19K-binding protein B5 inhibits apoptosis induced by Nip3 by forming a heterodimer through the C-terminal hydrophobic region". Cell Death Differ. ج. 6 ع. 4: 314–25. DOI:10.1038/sj.cdd.4400493. PMID:10381623.
Bouillet P، Metcalf D، Huang DC، وآخرون (1999). "Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity". Science. ج. 286 ع. 5445: 1735–8. DOI:10.1126/science.286.5445.1735. PMID:10576740.
Dijkers PF، Medema RH، Lammers JW، وآخرون (2000). "Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1". Curr. Biol. ج. 10 ع. 19: 1201–4. DOI:10.1016/S0960-9822(00)00728-4. PMID:11050388.
Bouillet P، Zhang LC، Huang DC، وآخرون (2001). "Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim". Mamm. Genome. ج. 12 ع. 2: 163–8. DOI:10.1007/s003350010242. PMID:11210187.
Putcha GV، Moulder KL، Golden JP، وآخرون (2001). "Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis". Neuron. ج. 29 ع. 3: 615–28. DOI:10.1016/S0896-6273(01)00238-0. PMID:11301022.
Murray S، Halford S، Ebenezer ND، وآخرون (2001). "Assignment of BCL2L11 to human chromosome band 2p13 with somatic cell and radiation hybrids". Cytogenet. Cell Genet. ج. 92 ع. 3–4: 353. DOI:10.1159/000056930. PMID:11435715.
Cheng EH، Wei MC، Weiler S، وآخرون (2001). "BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis". Mol. Cell. ج. 8 ع. 3: 705–11. DOI:10.1016/S1097-2765(01)00320-3. PMID:11583631.
Mami U، Miyashita T، Shikama Y، وآخرون (2002). "Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family". FEBS Lett. ج. 509 ع. 1: 135–41. DOI:10.1016/S0014-5793(01)03145-3. PMID:11734221.
Bouillet P، Purton JF، Godfrey DI، وآخرون (2002). "BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes". Nature. ج. 415 ع. 6874: 922–6. DOI:10.1038/415922a. PMID:11859372.
Marani M، Tenev T، Hancock D، وآخرون (2002). "Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis". Mol. Cell. Biol. ج. 22 ع. 11: 3577–89. DOI:10.1128/MCB.22.11.3577-3589.2002. PMC:133811. PMID:11997495.
Liu JW، Chandra D، Tang SH، وآخرون (2002). "Identification and characterization of Bimgamma, a novel proapoptotic BH3-only splice variant of Bim". Cancer Res. ج. 62 ع. 10: 2976–81. PMID:12019181.
Terradillos O، Montessuit S، Huang DC، Martinou JC (2002). "Direct addition of BimL to mitochondria does not lead to cytochrome c release". FEBS Lett. ج. 522 ع. 1–3: 29–34. DOI:10.1016/S0014-5793(02)02871-5. PMID:12095614.
Sugiyama T، Shimizu S، Matsuoka Y، وآخرون (2002). "Activation of mitochondrial voltage-dependent anion channel by apro-apoptotic BH3-only protein Bim". Oncogene. ج. 21 ع. 32: 4944–56. DOI:10.1038/sj.onc.1205621. PMID:12118373.

هذه بذرة مقالة عن جين على كروموسوم 2 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[pmid9430630-1] O'Connor L، Strasser A، O'Reilly LA، Hausmann G، Adams JM، Cory S، Huang DC (فبراير 1998). "Bim: a novel member of the Bcl-2 family that promotes apoptosis". EMBO J. ج. 17 ع. 2: 384–95. DOI:10.1093/emboj/17.2.384. PMC:1170389. PMID:9430630.

[pmid9731710-2] Hsu SY، Lin P، Hsueh AJ (نوفمبر 1998). "BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members". Mol Endocrinol. ج. 12 ع. 9: 1432–40. DOI:10.1210/mend.12.9.0166. PMID:9731710.

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