NRD1

An Error has occured retrieving Wikidata item for infobox NRD1‏ (Nardilysin convertase) هوَ بروتين يُشَفر بواسطة جين NRD1 في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ "Entrez Gene: NRD1 nardilysin (N-arginine dibasic convertase)". مؤرشف من الأصل في 2010-12-05.
^ Hospital V، Prat A، Joulie C، Cherif D، Day R، Cohen P (مايو 1998). "Human and rat testis express two mRNA species encoding variants of NRD convertase, a metalloendopeptidase of the insulinase family". Biochem J. ج. 327 ع. 3: 773–9. PMC:1218856. PMID:9581555.
^ Fumagalli P، Accarino M، Egeo A، Scartezzini P، Rappazzo G، Pizzuti A، Avvantaggiato V، Simeone A، Arrigo G، Zuffardi O، Ottolenghi S، Taramelli R (أبريل 1998). "Human NRD convertase: a highly conserved metalloendopeptidase expressed at specific sites during development and in adult tissues". Genomics. ج. 47 ع. 2: 238–45. DOI:10.1006/geno.1997.5078. PMID:9479496.

قراءة متعمقة

Seidah NG، Prat A (2003). "Precursor convertases in the secretory pathway, cytosol and extracellular milieu". Essays Biochem. ج. 38: 79–94. PMID:12463163.
Hospital V، Prat A (2005). "Nardilysin, a basic residues specific metallopeptidase that mediates cell migration and proliferation". Protein Pept. Lett. ج. 11 ع. 5: 501–8. DOI:10.2174/0929866043406508. PMID:15544571.
Winter AG، Pierotti AR (2001). "Gene expression of the dibasic-pair cleaving enzyme NRD convertase (N-arginine dibasic convertase) is differentially regulated in the GH3 pituitary and Mat-Lu prostate cell lines". Biochem. J. ج. 351 ع. 3: 755–64. DOI:10.1042/0264-6021:3510755. PMC:1221416. PMID:11042131.
Nishi E، Prat A، Hospital V، وآخرون (2001). "N-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor that mediates cell migration". EMBO J. ج. 20 ع. 13: 3342–50. DOI:10.1093/emboj/20.13.3342. PMC:125525. PMID:11432822.
Ma Z، Csuhai E، Chow KM، Hersh LB (2001). "Expression of the acidic stretch of nardilysin as a functional binding domain". Biochemistry. ج. 40 ع. 31: 9447–52. DOI:10.1021/bi010538x. PMID:11478915.
Hospital V، Nishi E، Klagsbrun M، وآخرون (2003). "The metalloendopeptidase nardilysin (NRDc) is potently inhibited by heparin-binding epidermal growth factor-like growth factor (HB-EGF)". Biochem. J. ج. 367 ع. Pt 1: 229–38. DOI:10.1042/BJ20020822. PMC:1222870. PMID:12095415.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Chow KM، Oakley O، Goodman J، وآخرون (2003). "Nardilysin cleaves peptides at monobasic sites". Biochemistry. ج. 42 ع. 7: 2239–44. DOI:10.1021/bi027178d. PMID:12590613.
Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
Kimura K، Wakamatsu A، Suzuki Y، وآخرون (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. ج. 16 ع. 1: 55–65. DOI:10.1101/gr.4039406. PMC:1356129. PMID:16344560.
Gregory SG، Barlow KF، McLay KE، وآخرون (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. ج. 441 ع. 7091: 315–21. Bibcode:2006Natur.441..315G. DOI:10.1038/nature04727. PMID:16710414.
Nishi E، Hiraoka Y، Yoshida K، وآخرون (2006). "Nardilysin enhances ectodomain shedding of heparin-binding epidermal growth factor-like growth factor through activation of tumor necrosis factor-alpha-converting enzyme". J. Biol. Chem. ج. 281 ع. 41: 31164–72. DOI:10.1074/jbc.M601316200. PMID:16923819.
Bernstein HG، Stricker R، Dobrowolny H، وآخرون (2007). "Histochemical evidence for wide expression of the metalloendopeptidase nardilysin in human brain neurons". Neuroscience. ج. 146 ع. 4: 1513–23. DOI:10.1016/j.neuroscience.2007.02.057. PMID:17442499.

هذه بذرة مقالة عن جين على كروموسوم 1 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[entrez-1] "Entrez Gene: NRD1 nardilysin (N-arginine dibasic convertase)". مؤرشف من الأصل في 2010-12-05.

[pmid9581555-2] Hospital V، Prat A، Joulie C، Cherif D، Day R، Cohen P (مايو 1998). "Human and rat testis express two mRNA species encoding variants of NRD convertase, a metalloendopeptidase of the insulinase family". Biochem J. ج. 327 ع. 3: 773–9. PMC:1218856. PMID:9581555.

[pmid9479496-3] Fumagalli P، Accarino M، Egeo A، Scartezzini P، Rappazzo G، Pizzuti A، Avvantaggiato V، Simeone A، Arrigo G، Zuffardi O، Ottolenghi S، Taramelli R (أبريل 1998). "Human NRD convertase: a highly conserved metalloendopeptidase expressed at specific sites during development and in adult tissues". Genomics. ج. 47 ع. 2: 238–45. DOI:10.1006/geno.1997.5078. PMID:9479496.

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