IFI16

An Error has occured retrieving Wikidata item for infobox IFI16‏ (Interferon gamma inducible protein 16) هوَ بروتين يُشَفر بواسطة جين IFI16 في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ Trapani JA، Dawson M، Apostolidis VA، Browne KA (ديسمبر 1994). "Genomic organization of IFI16, an interferon-inducible gene whose expression is associated with human myeloid cell differentiation: correlation of predicted protein domains with exon organization". Immunogenetics. ج. 40 ع. 6: 415–24. DOI:10.1007/bf00177824. PMID:7959953.
^ "Entrez Gene: IFI16 interferon, gamma-inducible protein 16". مؤرشف من الأصل في 2010-12-05.
^ Trapani JA، Browne KA، Dawson MJ، Ramsay RG، Eddy RL، Show TB، White PC، Dupont B (أكتوبر 1992). "A novel gene constitutively expressed in human lymphoid cells is inducible with interferon-gamma in myeloid cells". Immunogenetics. ج. 36 ع. 6: 369–76. DOI:10.1007/bf00218044. PMID:1526658.

قراءة متعمقة

Dawson MJ، Trapani JA (1995). "IFI 16 gene encodes a nuclear protein whose expression is induced by interferons in human myeloid leukaemia cell lines". J. Cell. Biochem. ج. 57 ع. 1: 39–51. DOI:10.1002/jcb.240570106. PMID:7536752.
Dawson MJ، Trapani JA، Briggs RC، وآخرون (1995). "The closely linked genes encoding the myeloid nuclear differentiation antigen (MNDA) and IFI16 exhibit contrasting haemopoietic expression". Immunogenetics. ج. 41 ع. 1: 40–3. DOI:10.1007/BF00188431. PMID:7806273.
Johnstone RW، Kerry JA، Trapani JA (1998). "The human interferon-inducible protein, IFI 16, is a repressor of transcription". J. Biol. Chem. ج. 273 ع. 27: 17172–7. DOI:10.1074/jbc.273.27.17172. PMID:9642285.
Johnstone RW، Kershaw MH، Trapani JA (1998). "Isotypic variants of the interferon-inducible transcriptional repressor IFI 16 arise through differential mRNA splicing". Biochemistry. ج. 37 ع. 34: 11924–31. DOI:10.1021/bi981069a. PMID:9718316.
Dawson MJ، Elwood NJ، Johnstone RW، Trapani JA (1998). "The IFN-inducible nucleoprotein IFI 16 is expressed in cells of the monocyte lineage, but is rapidly and markedly down-regulated in other myeloid precursor populations". J. Leukoc. Biol. ج. 64 ع. 4: 546–54. PMID:9766636.
Briggs LJ، Johnstone RW، Elliot RM، وآخرون (2001). "Novel properties of the protein kinase CK2-site-regulated nuclear- localization sequence of the interferon-induced nuclear factor IFI 16". Biochem. J. ج. 353 ع. Pt 1: 69–77. DOI:10.1042/0264-6021:3530069. PMC:1221544. PMID:11115400.
Johnstone RW، Wei W، Greenway A، Trapani JA (2001). "Functional interaction between p53 and the interferon-inducible nucleoprotein IFI 16". Oncogene. ج. 19 ع. 52: 6033–42. DOI:10.1038/sj.onc.1204005. PMID:11146555.
Gariglio M، Azzimonti B، Pagano M، وآخرون (2003). "Immunohistochemical expression analysis of the human interferon-inducible gene IFI16, a member of the HIN200 family, not restricted to hematopoietic cells". J. Interferon Cytokine Res. ج. 22 ع. 7: 815–21. DOI:10.1089/107999002320271413. PMID:12184920.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Izmailova E، Bertley FM، Huang Q، وآخرون (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages". Nat. Med. ج. 9 ع. 2: 191–7. DOI:10.1038/nm822. PMID:12539042.
Clarke CJ، Apostolidis V، Hii LL، وآخرون (2003). "Critical role of the transcription factor AP-1 for the constitutive and interferon-induced expression of IFI 16". J. Cell. Biochem. ج. 89 ع. 1: 80–93. DOI:10.1002/jcb.10475. PMID:12682910.
Xin H، Curry J، Johnstone RW، وآخرون (2003). "Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence". Oncogene. ج. 22 ع. 31: 4831–40. DOI:10.1038/sj.onc.1206754. PMID:12894224.
Kwak JC، Ongusaha PP، Ouchi T، Lee SW (2003). "IFI16 as a negative regulator in the regulation of p53 and p21(Waf1)". J. Biol. Chem. ج. 278 ع. 42: 40899–904. DOI:10.1074/jbc.M308012200. PMID:12925527.
Aglipay JA، Lee SW، Okada S، وآخرون (2004). "A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway". Oncogene. ج. 22 ع. 55: 8931–8. DOI:10.1038/sj.onc.1207057. PMID:14654789.
Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
Raffaella R، Gioia D، De Andrea M، وآخرون (2004). "The interferon-inducible IFI16 gene inhibits tube morphogenesis and proliferation of primary, but not HPV16 E6/E7-immortalized human endothelial cells". Exp. Cell Res. ج. 293 ع. 2: 331–45. DOI:10.1016/j.yexcr.2003.10.014. PMID:14729471.
Fujiuchi N، Aglipay JA، Ohtsuka T، وآخرون (2004). "Requirement of IFI16 for the maximal activation of p53 induced by ionizing radiation". J. Biol. Chem. ج. 279 ع. 19: 20339–44. DOI:10.1074/jbc.M400344200. PMID:14990579.
Beausoleil SA، Jedrychowski M، Schwartz D، وآخرون (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. ج. 101 ع. 33: 12130–5. DOI:10.1073/pnas.0404720101. PMC:514446. PMID:15302935.

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[pmid7959953-1] Trapani JA، Dawson M، Apostolidis VA، Browne KA (ديسمبر 1994). "Genomic organization of IFI16, an interferon-inducible gene whose expression is associated with human myeloid cell differentiation: correlation of predicted protein domains with exon organization". Immunogenetics. ج. 40 ع. 6: 415–24. DOI:10.1007/bf00177824. PMID:7959953.

[entrez-2] "Entrez Gene: IFI16 interferon, gamma-inducible protein 16". مؤرشف من الأصل في 2010-12-05.

[pmid1526658-3] Trapani JA، Browne KA، Dawson MJ، Ramsay RG، Eddy RL، Show TB، White PC، Dupont B (أكتوبر 1992). "A novel gene constitutively expressed in human lymphoid cells is inducible with interferon-gamma in myeloid cells". Immunogenetics. ج. 36 ع. 6: 369–76. DOI:10.1007/bf00218044. PMID:1526658.

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