BCCIP

An Error has occured retrieving Wikidata item for infobox BCCIP‏ (BRCA2 and CDKN1A interacting protein) هوَ بروتين يُشَفر بواسطة جين BCCIP في الإنسان.^[1]^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ ^أ ^ب "Entrez Gene: BCCIP BRCA2 and CDKN1A interacting protein". مؤرشف من الأصل في 2010-12-05.
^ Liu J، Yuan Y، Huan J، Shen Z (أبريل 2001). "Inhibition of breast and brain cancer cell growth by BCCIPalpha, an evolutionarily conserved nuclear protein that interacts with BRCA2". Oncogene. ج. 20 ع. 3: 336–45. DOI:10.1038/sj.onc.1204098. PMID:11313963.
^ Ono T، Kitaura H، Ugai H، Murata T، Yokoyama KK، Iguchi-Ariga SM، Ariga H (أكتوبر 2000). "TOK-1, a novel p21Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinase". J Biol Chem. ج. 275 ع. 40: 31145–54. DOI:10.1074/jbc.M003031200. PMID:10878006.

قراءة متعمقة

Coleman RA، Rao P، Fogelsong RJ، Bardes ES (1992). "2-Bromopalmitoyl-CoA and 2-bromopalmitate: promiscuous inhibitors of membrane-bound enzymes". Biochim. Biophys. Acta. ج. 1125 ع. 2: 203–9. DOI:10.1016/0005-2760(92)90046-X. PMID:1571364.
Machackova E، Damborsky J، Valik D، Foretova L (2002). "Novel germline BRCA1 and BRCA2 mutations in breast and breast/ovarian cancer families from the Czech Republic". Hum. Mutat. ج. 18 ع. 6: 545. DOI:10.1002/humu.1232. PMID:11748848.
Armakolas A، Ladopoulou A، Konstantopoulou I، وآخرون (2002). "BRCA2 gene mutations in Greek patients with familial breast cancer". Hum. Mutat. ج. 19 ع. 1: 81–2. DOI:10.1002/humu.9003. PMID:11754111.
Robson M، Scheuer L، Nafa K، وآخرون (2002). "Unique de novo mutation of BRCA2 in a woman with early onset breast cancer". J. Med. Genet. ج. 39 ع. 2: 126–8. DOI:10.1136/jmg.39.2.126. PMC:1735025. PMID:11836363.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Meng X، Liu J، Shen Z (2003). "Genomic structure of the human BCCIP gene and its expression in cancer". Gene. ج. 302 ع. 1–2: 139–46. DOI:10.1016/S0378-1119(02)01098-3. PMID:12527204.
Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
Meng X، Liu J، Shen Z (2004). "Inhibition of G1 to S cell cycle progression by BCCIP beta". Cell Cycle. ج. 3 ع. 3: 343–8. DOI:10.4161/cc.3.3.672. PMID:14726710.
Deloukas P، Earthrowl ME، Grafham DV، وآخرون (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. ج. 429 ع. 6990: 375–81. DOI:10.1038/nature02462. PMID:15164054.
Colland F، Jacq X، Trouplin V، وآخرون (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. ج. 14 ع. 7: 1324–32. DOI:10.1101/gr.2334104. PMC:442148. PMID:15231748.
Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
Meng X، Lu H، Shen Z (2007). "BCCIP functions through p53 to regulate the expression of p21Waf1/Cip1". Cell Cycle. ج. 3 ع. 11: 1457–62. DOI:10.4161/cc.3.11.1213. PMID:15539944.
Lu H، Guo X، Meng X، وآخرون (2005). "The BRCA2-interacting protein BCCIP functions in RAD51 and BRCA2 focus formation and homologous recombinational repair". Mol. Cell. Biol. ج. 25 ع. 5: 1949–57. DOI:10.1128/MCB.25.5.1949-1957.2005. PMC:549367. PMID:15713648.
Stelzl U، Worm U، Lalowski M، وآخرون (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. ج. 122 ع. 6: 957–68. DOI:10.1016/j.cell.2005.08.029. PMID:16169070.
Rual JF، Venkatesan K، Hao T، وآخرون (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. ج. 437 ع. 7062: 1173–8. DOI:10.1038/nature04209. PMID:16189514.
Olsen JV، Blagoev B، Gnad F، وآخرون (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. ج. 127 ع. 3: 635–48. DOI:10.1016/j.cell.2006.09.026. PMID:17081983.
Meng X، Yue J، Liu Z، Shen Z (2007). "Abrogation of the transactivation activity of p53 by BCCIP down-regulation". J. Biol. Chem. ج. 282 ع. 3: 1570–6. DOI:10.1074/jbc.M607520200. PMC:2679999. PMID:17135243.
Ewing RM، Chu P، Elisma F، وآخرون (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. ج. 3 ع. 1: 89. DOI:10.1038/msb4100134. PMC:1847948. PMID:17353931.

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

[entrez-1] أ ^ب "Entrez Gene: BCCIP BRCA2 and CDKN1A interacting protein". مؤرشف من الأصل في 2010-12-05.

[pmid11313963-2] Liu J، Yuan Y، Huan J، Shen Z (أبريل 2001). "Inhibition of breast and brain cancer cell growth by BCCIPalpha, an evolutionarily conserved nuclear protein that interacts with BRCA2". Oncogene. ج. 20 ع. 3: 336–45. DOI:10.1038/sj.onc.1204098. PMID:11313963.

[pmid10878006-3] Ono T، Kitaura H، Ugai H، Murata T، Yokoyama KK، Iguchi-Ariga SM، Ariga H (أكتوبر 2000). "TOK-1, a novel p21Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinase". J Biol Chem. ج. 275 ع. 40: 31145–54. DOI:10.1074/jbc.M003031200. PMID:10878006.

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