TPX2

An Error has occured retrieving Wikidata item for infobox TPX2‏ (TPX2, microtubule nucleation factor) هوَ بروتين يُشَفر بواسطة جين TPX2 في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ Zhang Y، Heidebrecht H، Rott A، Schlegelberger B، Parwaresch R (يوليو 1999). "Assignment of human proliferation associated p100 gene (C20orf1) to human chromosome band 20q11.2 by in situ hybridization". Cytogenet Cell Genet. ج. 84 ع. 3–4: 182–3. DOI:10.1159/000015251. PMID:10393424.
^ Heidebrecht HJ، Buck F، Steinmann J، Sprenger R، Wacker HH، Parwaresch R (يوليو 1997). "p100: a novel proliferation-associated nuclear protein specifically restricted to cell cycle phases S, G2, and M". Blood. ج. 90 ع. 1: 226–33. PMID:9207457.
^ "Entrez Gene: TPX2 TPX2, microtubule-associated, homolog (Xenopus laevis)". مؤرشف من الأصل في 2010-12-05.

قراءة متعمقة

Manda R، Kohno T، Matsuno Y، وآخرون (1999). "Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display". Genomics. ج. 61 ع. 1: 5–14. DOI:10.1006/geno.1999.5939. PMID:10512675.
Wittmann T، Wilm M، Karsenti E، Vernos I (2000). "TPX2, A novel xenopus MAP involved in spindle pole organization". J. Cell Biol. ج. 149 ع. 7: 1405–18. DOI:10.1083/jcb.149.7.1405. PMC:2175143. PMID:10871281.
Deloukas P، Matthews LH، Ashurst J، وآخرون (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. ج. 414 ع. 6866: 865–71. Bibcode:2001Natur.414..865D. DOI:10.1038/414865a. PMID:11780052.
Wang Y، Han KJ، Pang XW، وآخرون (2002). "Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies". J. Immunol. ج. 169 ع. 2: 1102–9. DOI:10.4049/jimmunol.169.2.1102. PMID:12097419.
Kufer TA، Silljé HH، Körner R، وآخرون (2002). "Human TPX2 is required for targeting Aurora-A kinase to the spindle". J. Cell Biol. ج. 158 ع. 4: 617–23. DOI:10.1083/jcb.200204155. PMC:2174010. PMID:12177045.
Gruss OJ، Wittmann M، Yokoyama H، وآخرون (2004). "Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells". Nat. Cell Biol. ج. 4 ع. 11: 871–9. DOI:10.1038/ncb870. PMID:12389033.
Garrett S، Auer K، Compton DA، Kapoor TM (2003). "hTPX2 is required for normal spindle morphology and centrosome integrity during vertebrate cell division". Curr. Biol. ج. 12 ع. 23: 2055–9. DOI:10.1016/S0960-9822(02)01277-0. PMID:12477396.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Heidebrecht HJ، Adam-Klages S، Szczepanowski M، وآخرون (2004). "repp86: A human protein associated in the progression of mitosis". Mol. Cancer Res. ج. 1 ع. 4: 271–9. PMID:12612055.
Bayliss R، Sardon T، Vernos I، Conti E (2003). "Structural basis of Aurora-A activation by TPX2 at the mitotic spindle". Mol. Cell. ج. 12 ع. 4: 851–62. DOI:10.1016/S1097-2765(03)00392-7. PMID:14580337.
Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
Cassimeris L، Morabito J (2004). "TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly". Mol. Biol. Cell. ج. 15 ع. 4: 1580–90. DOI:10.1091/mbc.E03-07-0544. PMC:379257. PMID:14718566.
Beausoleil SA، Jedrychowski M، Schwartz D، وآخرون (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. ج. 101 ع. 33: 12130–5. Bibcode:2004PNAS..10112130B. DOI:10.1073/pnas.0404720101. PMC:514446. PMID:15302935.
Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
Maxwell CA، Keats JJ، Belch AR، وآخرون (2005). "Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity". Cancer Res. ج. 65 ع. 3: 850–60. PMID:15705883.
Stewart S، Fang G (2005). "Anaphase-promoting complex/cyclosome controls the stability of TPX2 during mitotic exit". Mol. Cell. Biol. ج. 25 ع. 23: 10516–27. DOI:10.1128/MCB.25.23.10516-10527.2005. PMC:1291225. PMID:16287863.
Ma Y، Lin D، Sun W، وآخرون (2006). "Expression of targeting protein for xklp2 associated with both malignant transformation of respiratory epithelium and progression of squamous cell lung cancer". Clin. Cancer Res. ج. 12 ع. 4: 1121–7. DOI:10.1158/1078-0432.CCR-05-1766. PMID:16489064.
Nousiainen M، Silljé HH، Sauer G، وآخرون (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. ج. 103 ع. 14: 5391–6. Bibcode:2006PNAS..103.5391N. DOI:10.1073/pnas.0507066103. PMC:1459365. PMID:16565220.

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

[pmid10393424-1] Zhang Y، Heidebrecht H، Rott A، Schlegelberger B، Parwaresch R (يوليو 1999). "Assignment of human proliferation associated p100 gene (C20orf1) to human chromosome band 20q11.2 by in situ hybridization". Cytogenet Cell Genet. ج. 84 ع. 3–4: 182–3. DOI:10.1159/000015251. PMID:10393424.

[pmid9207457-2] Heidebrecht HJ، Buck F، Steinmann J، Sprenger R، Wacker HH، Parwaresch R (يوليو 1997). "p100: a novel proliferation-associated nuclear protein specifically restricted to cell cycle phases S, G2, and M". Blood. ج. 90 ع. 1: 226–33. PMID:9207457.

[entrez-3] "Entrez Gene: TPX2 TPX2, microtubule-associated, homolog (Xenopus laevis)". مؤرشف من الأصل في 2010-12-05.

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