TFAP2C

An Error has occured retrieving Wikidata item for infobox TFAP2C‏ (Transcription factor AP-2 gamma) هوَ بروتين يُشَفر بواسطة جين TFAP2C في الإنسان.

الوظيفة

هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.

الأهمية السريرية

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قراءة متعمقة

• "Transcription factor AP-2gamma, a novel marker of gonocytes and seminomatous germ cell tumors". Int. J. Cancer. 115 (3): 470–7. 2005. doi:10.1002/ijc.20913. PMID 15700319.
• "Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor". Cancer Res. 64 (22): 8256–61. 2004. doi:10.1158/0008-5472.CAN-04-2055. PMID 15548692.
• "Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure". Clin. Cancer Res. 15 (11): 3672–9. 2009. doi:10.1158/1078-0432.CCR-08-2343. PMC 2776721. PMID 19458056.
• "AP-2gamma promotes proliferation in breast tumour cells by direct repression of the CDKN1A gene". EMBO J. 28 (22): 3591–601. 2009. doi:10.1038/emboj.2009.290. PMC 2782101. PMID 19798054.
• "AP-2alpha and AP-2gamma regulate tumor progression via specific genetic programs". FASEB J. 22 (8): 2702–14. 2008. doi:10.1096/fj.08-106492. PMID 18443366.
• "AP-2alpha and AP-2gamma are transcriptional targets of p53 in human breast carcinoma cells". Oncogene. 25 (39): 5405–15. 2006. doi:10.1038/sj.onc.1209534. PMID 16636674.
• "Elevated expression levels of NCOA3, TOP1, and TFAP2C in breast tumors as predictors of poor prognosis". Cancer. 98 (1): 18–23. 2003. doi:10.1002/cncr.11482. PMID 12833450.
• "Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis". Clin. Cancer Res. 10 (22): 7621–8. 2004. doi:10.1158/1078-0432.CCR-04-1061. PMID 15569994.
• "TFAP2C controls hormone response in breast cancer cells through multiple pathways of estrogen signaling". Cancer Res. 67 (18): 8439–43. 2007. doi:10.1158/0008-5472.CAN-07-2293. PMID 17875680.
• "Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2". J. Biol. Chem. 278 (18): 16021–9. 2003. doi:10.1074/jbc.M208144200. PMID 12586840.
• "Immunohistochemical expression patterns of AP2alpha and AP2gamma in the developing fetal human breast". Histopathology. 51 (6): 814–23. 2007. doi:10.1111/j.1365-2559.2007.02887.x. PMID 18042070.
• "AP-2gamma induces p21 expression, arrests cell cycle, and inhibits the tumor growth of human carcinoma cells". Neoplasia. 8 (7): 568–77. 2006. doi:10.1593/neo.06367. PMC 1601932. PMID 16867219.
• "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• "Sp1 and Sp3 Are important regulators of AP-2gamma gene transcription". Biol. Reprod. 69 (4): 1220–30. 2003. doi:10.1095/biolreprod.103.015545. PMID 12801994.
• "Activator protein-2gamma (AP-2gamma) expression is specifically induced by oestrogens through binding of the oestrogen receptor to a canonical element within the 5'-untranslated region". Biochem. J. 377 (Pt 2): 429–38. 2004. doi:10.1042/BJ20031133. PMC 1223884. PMID 14565844.
• "Fragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in breast cancer". Cancer. 115 (4): 899–908. 2009. doi:10.1002/cncr.24103. PMC 2640223. PMID 19130459.
• "Wwox and Ap2gamma expression levels predict tamoxifen response". Clin. Cancer Res. 13 (20): 6115–21. 2007. doi:10.1158/1078-0432.CCR-07-1282. PMID 17947476.
• "Activator protein-2 impairs the invasion of a human extravillous trophoblast cell line". Endocrinology. 150 (9): 4376–85. 2009. doi:10.1210/en.2008-1645. PMID 19443578.
• "Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells". BMC Cancer. 9: 279. 2009. doi:10.1186/1471-2407-9-279. PMC 3224728. PMID 19671168.

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