PTPRN2

An Error has occured retrieving Wikidata item for infobox PTPRN2‏ (Protein tyrosine phosphatase, receptor type N2) هوَ بروتين يُشَفر بواسطة جين PTPRN2 في الإنسان.^[1]^[2]^[1]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ ^أ ^ب "Entrez Gene: PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2". مؤرشف من الأصل في 2010-03-07.
^ Li Q، Borovitskaya AE، DeSilva MG، Wasserfall C، Maclaren NK، Notkins AL، Lan MS (سبتمبر 1997). "Autoantigens in insulin-dependent diabetes mellitus: molecular cloning and characterization of human IA-2 beta". Proc Assoc Am Physicians. ج. 109 ع. 4: 429–39. PMID:9220540.
^ Smith PD، Barker KT، Wang J، Lu YJ، Shipley J، Crompton MR (يناير 1997). "ICAAR, a novel member of a new family of transmembrane, tyrosine phosphatase-like proteins". Biochem Biophys Res Commun. ج. 229 ع. 2: 402–11. DOI:10.1006/bbrc.1996.1817. PMID:8954911.

قراءة متعمقة

Lan MS، Lu J، Goto Y، Notkins AL (1994). "Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2, from human insulinoma". DNA Cell Biol. ج. 13 ع. 5: 505–14. DOI:10.1089/dna.1994.13.505. PMID:8024693.
Cui L، Yu WP، DeAizpurua HJ، وآخرون (1996). "Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes". J. Biol. Chem. ج. 271 ع. 40: 24817–23. DOI:10.1074/jbc.271.40.24817. PMID:8798755.
Kawasaki E، Hutton JC، Eisenbarth GS (1996). "Molecular cloning and characterization of the human transmembrane protein tyrosine phosphatase homologue, phogrin, an autoantigen of type 1 diabetes". Biochem. Biophys. Res. Commun. ج. 227 ع. 2: 440–7. DOI:10.1006/bbrc.1996.1526. PMID:8878534.
Schmidli RS، Colman PG، Cui L، وآخرون (1998). "Antibodies to the protein tyrosine phosphatases IAR and IA-2 are associated with progression to insulin-dependent diabetes (IDDM) in first-degree relatives at-risk for IDDM". Autoimmunity. ج. 28 ع. 1: 15–23. DOI:10.3109/08916939808993841. PMID:9754810.
van den Maagdenberg AM، Schepens JT، Schepens MT، وآخرون (1999). "Assignment of Ptprn2, the gene encoding receptor-type protein tyrosine phosphatase IA-2beta, a major autoantigen in insulin-dependent diabetes mellitus, to mouse chromosome region 12F". Cytogenet. Cell Genet. ج. 82 ع. 3–4: 153–5. DOI:10.1159/000015090. PMID:9858807.
Berghs S، Aggujaro D، Dirkx R، وآخرون (2001). "betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system". J. Cell Biol. ج. 151 ع. 5: 985–1002. DOI:10.1083/jcb.151.5.985. PMC:2174349. PMID:11086001.
Kubosaki A، Gross S، Miura J، وآخرون (2004). "Targeted disruption of the IA-2beta gene causes glucose intolerance and impairs insulin secretion but does not prevent the development of diabetes in NOD mice". Diabetes. ج. 53 ع. 7: 1684–91. DOI:10.2337/diabetes.53.7.1684. PMID:15220191.
Lim J، Hao T، Shaw C، وآخرون (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. ج. 125 ع. 4: 801–14. DOI:10.1016/j.cell.2006.03.032. PMID:16713569.

هذه بذرة مقالة عن جين على كروموسوم 7 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[entrez-1] أ ^ب "Entrez Gene: PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2". مؤرشف من الأصل في 2010-03-07.

[pmid9220540-2] Li Q، Borovitskaya AE، DeSilva MG، Wasserfall C، Maclaren NK، Notkins AL، Lan MS (سبتمبر 1997). "Autoantigens in insulin-dependent diabetes mellitus: molecular cloning and characterization of human IA-2 beta". Proc Assoc Am Physicians. ج. 109 ع. 4: 429–39. PMID:9220540.

[pmid8954911-3] Smith PD، Barker KT، Wang J، Lu YJ، Shipley J، Crompton MR (يناير 1997). "ICAAR, a novel member of a new family of transmembrane, tyrosine phosphatase-like proteins". Biochem Biophys Res Commun. ج. 229 ع. 2: 402–11. DOI:10.1006/bbrc.1996.1817. PMID:8954911.

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