SHC3
من أرابيكا، الموسوعة العربية الحرة
المزيد من اللغات
المزيد من الإجراءات
An Error has occured retrieving Wikidata item for infobox SHC3 (SHC adaptor protein 3) هوَ بروتين يُشَفر بواسطة جين SHC3 في الإنسان.[1][2]
الوظيفة
![[أيقونة]](/%D9%85%D9%84%D9%81:Crystal_xedit.svg){kind=small} | هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
| هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
- ^ Nakamura T؛ Sanokawa R؛ Sasaki Y؛ Ayusawa D؛ Oishi M؛ Mori N (نوفمبر 1996). "N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway". Oncogene. ج. 13 ع. 6: 1111–21. PMID:8808684.
- ^ "Entrez Gene: SHC3 SHC (Src homology 2 domain containing) transforming protein 3". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- O'Bryan JP، Songyang Z، Cantley L، وآخرون (1996). "A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain". Proc. Natl. Acad. Sci. U.S.A. ج. 93 ع. 7: 2729–34. Bibcode:1996PNAS...93.2729O. DOI:10.1073/pnas.93.7.2729. PMC:39699. PMID:8610109.
- Pelicci G، Dente L، De Giuseppe A، وآخرون (1996). "A family of Shc related proteins with conserved PTB, CH1 and SH2 regions". Oncogene. ج. 13 ع. 3: 633–41. PMID:8760305.
- Menegon A؛ Leoni C؛ Benfenati F؛ Valtorta F (1997). "Tat protein from HIV-1 activates MAP kinase in granular neurons and glial cells from rat cerebellum". Biochem. Biophys. Res. Commun. ج. 238 ع. 3: 800–5. DOI:10.1006/bbrc.1997.7393. PMID:9325171.
- Wang JF، Ganju RK، Liu ZY، وآخرون (1997). "Signal transduction in human hematopoietic cells by vascular endothelial growth factor related protein, a novel ligand for the FLT4 receptor". Blood. ج. 90 ع. 9: 3507–15. PMID:9345034.
- Nakamura T؛ Muraoka S؛ Sanokawa R؛ Mori N (1998). "N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling". J. Biol. Chem. ج. 273 ع. 12: 6960–7. DOI:10.1074/jbc.273.12.6960. PMID:9507002.
- Cook KK؛ Fadool DA (2002). "Two adaptor proteins differentially modulate the phosphorylation and biophysics of Kv1.3 ion channel by SRC kinase". J. Biol. Chem. ج. 277 ع. 15: 13268–80. DOI:10.1074/jbc.M108898200. PMC:2779217. PMID:11812778.
- Tarr PE، Roncarati R، Pelicci G، وآخرون (2002). "Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc". J. Biol. Chem. ج. 277 ع. 19: 16798–804. DOI:10.1074/jbc.M110286200. PMID:11877420.
- Liu HY؛ Meakin SO (2002). "ShcB and ShcC activation by the Trk family of receptor tyrosine kinases". J. Biol. Chem. ج. 277 ع. 29: 26046–56. DOI:10.1074/jbc.M111659200. PMID:12006576.
- Miyake I، Hakomori Y، Shinohara A، وآخرون (2002). "Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines". Oncogene. ج. 21 ع. 38: 5823–34. DOI:10.1038/sj.onc.1205735. PMID:12185581.
- Pelicci G، Troglio F، Bodini A، وآخرون (2002). "The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway". Mol. Cell. Biol. ج. 22 ع. 20: 7351–63. DOI:10.1128/MCB.22.20.7351-7363.2002. PMC:139827. PMID:12242309.
- Nakamura T، Komiya M، Sone K، وآخرون (2003). "Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter molecules". Mol. Cell. Biol. ج. 22 ع. 24: 8721–34. DOI:10.1128/MCB.22.24.8721-8734.2002. PMC:139861. PMID:12446789.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Miyake I، Hakomori Y، Misu Y، وآخرون (2005). "Domain-specific function of ShcC docking protein in neuroblastoma cells". Oncogene. ج. 24 ع. 19: 3206–15. DOI:10.1038/sj.onc.1208523. PMID:15735675.
- Magrassi L، Conti L، Lanterna A، وآخرون (2005). "Shc3 affects human high-grade astrocytomas survival". Oncogene. ج. 24 ع. 33: 5198–206. DOI:10.1038/sj.onc.1208708. PMID:15870690.
- De Falco V، Guarino V، Malorni L، وآخرون (2005). "RAI(ShcC/N-Shc)-dependent recruitment of GAB 1 to RET oncoproteins potentiates PI 3-K signalling in thyroid tumors". Oncogene. ج. 24 ع. 41: 6303–13. DOI:10.1038/sj.onc.1208776. PMID:15940252.
- Toschi E، Bacigalupo I، Strippoli R، وآخرون (2006). "HIV-1 Tat regulates endothelial cell cycle progression via activation of the Ras/ERK MAPK signaling pathway". Mol. Biol. Cell. ج. 17 ع. 4: 1985–94. DOI:10.1091/mbc.E05-08-0717. PMC:1415297. PMID:16436505.
- Li MD، Sun D، Lou XY، وآخرون (2007). "Linkage and association studies in African- and Caucasian-American populations demonstrate that SHC3 is a novel susceptibility locus for nicotine dependence". Mol. Psychiatry. ج. 12 ع. 5: 462–73. DOI:10.1038/sj.mp.4001933. PMID:17179996.
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