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HGFAC
An Error has occured retrieving Wikidata item for infobox HGFAC (HGF activator) هوَ بروتين يُشَفر بواسطة جين HGFAC في الإنسان.[1][2][3]
الوظيفة
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
- ^ Shimomura T، Kondo J، Ochiai M، Naka D، Miyazawa K، Morimoto Y، Kitamura N (ديسمبر 1993). "Activation of the zymogen of hepatocyte growth factor activator by thrombin". J Biol Chem. ج. 268 ع. 30: 22927–32. PMID:8226803.
- ^ "Entrez Gene: HGFAC HGF activator". مؤرشف من الأصل في 2010-12-05.
- ^ Miyazawa K، Shimomura T، Kitamura A، Kondo J، Morimoto Y، Kitamura N (يونيو 1993). "Molecular Cloning and Sequence Analysis of the cDNA for a Human Serine Protease Responsible for Activation of Hepatocyte Growth Factor. Structural similarity of the protease precursor to blood coagulation factor XII". J Biol Chem. ج. 268 ع. 14: 10024–8. PMID:7683665.
قراءة متعمقة
- Nakamura T (1992). "Structure and function of hepatocyte growth factor". Prog. Growth Factor Res. ج. 3 ع. 1: 67–85. DOI:10.1016/0955-2235(91)90014-U. PMID:1838014.
- Shimomura T، Ochiai M، Kondo J، Morimoto Y (1992). "A novel protease obtained from FBS-containing culture supernatant, that processes single chain form hepatocyte growth factor to two chain form in serum-free culture". Cytotechnology. ج. 8 ع. 3: 219–29. DOI:10.1007/BF02522039. PMID:1368819.
- Miyazawa K، Shimomura T، Kitamura N (1996). "Activation of hepatocyte growth factor in the injured tissues is mediated by hepatocyte growth factor activator". J. Biol. Chem. ج. 271 ع. 7: 3615–8. DOI:10.1074/jbc.271.7.3615. PMID:8631970.
- Shimomura T، Denda K، Kitamura A، وآخرون (1997). "Hepatocyte growth factor activator inhibitor, a novel Kunitz-type serine protease inhibitor". J. Biol. Chem. ج. 272 ع. 10: 6370–6. DOI:10.1074/jbc.272.10.6370. PMID:9045658.
- Kawaguchi T، Qin L، Shimomura T، وآخرون (1997). "Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor". J. Biol. Chem. ج. 272 ع. 44: 27558–64. DOI:10.1074/jbc.272.44.27558. PMID:9346890.
- Miyazawa K، Wang Y، Minoshima S، وآخرون (1999). "Structural organization and chromosomal localization of the human hepatocyte growth factor activator gene--phylogenetic and functional relationship with blood coagulation factor XII, urokinase, and tissue-type plasminogen activator". Eur. J. Biochem. ج. 258 ع. 2: 355–61. DOI:10.1046/j.1432-1327.1998.2580355.x. PMID:9874200.
- Kataoka H، Shimomura T، Kawaguchi T، وآخرون (2001). "Hepatocyte growth factor activator inhibitor type 1 is a specific cell surface binding protein of hepatocyte growth factor activator (HGFA) and regulates HGFA activity in the pericellular microenvironment". J. Biol. Chem. ج. 275 ع. 51: 40453–62. DOI:10.1074/jbc.M006412200. PMID:11013244.
- Kataoka H، Meng JY، Itoh H، وآخرون (2001). "Localization of hepatocyte growth factor activator inhibitor type 1 in Langhans' cells of human placenta". Histochem. Cell Biol. ج. 114 ع. 6: 469–75. DOI:10.1007/s004180000228. PMID:11201608.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Anderson NL، Polanski M، Pieper R، وآخرون (2004). "The human plasma proteome: a nonredundant list developed by combination of four separate sources". Mol. Cell. Proteomics. ج. 3 ع. 4: 311–26. DOI:10.1074/mcp.M300127-MCP200. PMID:14718574.
- Tjin EP، Derksen PW، Kataoka H، وآخرون (2004). "Multiple myeloma cells catalyze hepatocyte growth factor (HGF) activation by secreting the serine protease HGF-activator". Blood. ج. 104 ع. 7: 2172–5. DOI:10.1182/blood-2003-12-4386. PMID:15172968.
- Zhang Z، Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. ج. 13 ع. 10: 2819–24. DOI:10.1110/ps.04682504. PMC:2286551. PMID:15340161.
- Shia S، Stamos J، Kirchhofer D، وآخرون (2005). "Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B". J. Mol. Biol. ج. 346 ع. 5: 1335–49. DOI:10.1016/j.jmb.2004.12.048. PMID:15713485.
- Tjin EP، Groen RW، Vogelzang I، وآخرون (2006). "Functional analysis of HGF/MET signaling and aberrant HGF-activator expression in diffuse large B-cell lymphoma". Blood. ج. 107 ع. 2: 760–8. DOI:10.1182/blood-2005-05-1929. PMID:16189274.
- Liu T، Qian WJ، Gritsenko MA، وآخرون (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. ج. 4 ع. 6: 2070–80. DOI:10.1021/pr0502065. PMC:1850943. PMID:16335952.