ANTXR2

An Error has occured retrieving Wikidata item for infobox ANTXR2‏ (ANTXR cell adhesion molecule 2) هوَ بروتين يُشَفر بواسطة جين ANTXR2 في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ Bell SE، Mavila A، Salazar R، Bayless KJ، Kanagala S، Maxwell SA، Davis GE (أكتوبر 2001). "Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling". J Cell Sci. ج. 114 ع. Pt 15: 2755–73. PMID:11683410.
^ "Entrez Gene: ANTXR2 anthrax toxin receptor 2". مؤرشف من الأصل في 2010-03-07.
^ Scobie HM، Rainey GJ، Bradley KA، Young JA (أبريل 2003). "Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor". Proc Natl Acad Sci U S A. ج. 100 ع. 9: 5170–4. DOI:10.1073/pnas.0431098100. PMC:154317. PMID:12700348.

قراءة متعمقة

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Abrami L، Liu S، Cosson P، وآخرون (2003). "Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent process". J. Cell Biol. ج. 160 ع. 3: 321–8. DOI:10.1083/jcb.200211018. PMC:2172673. PMID:12551953.
Dowling O، Difeo A، Ramirez MC، وآخرون (2003). "Mutations in capillary morphogenesis gene-2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis". Am. J. Hum. Genet. ج. 73 ع. 4: 957–66. DOI:10.1086/378781. PMC:1180616. PMID:12973667.
Hanks S، Adams S، Douglas J، وآخرون (2003). "Mutations in the gene encoding capillary morphogenesis protein 2 cause juvenile hyaline fibromatosis and infantile systemic hyalinosis". Am. J. Hum. Genet. ج. 73 ع. 4: 791–800. DOI:10.1086/378418. PMC:1180602. PMID:14508707.
Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
Wigelsworth DJ، Krantz BA، Christensen KA، وآخرون (2004). "Binding stoichiometry and kinetics of the interaction of a human anthrax toxin receptor, CMG2, with protective antigen". J. Biol. Chem. ج. 279 ع. 22: 23349–56. DOI:10.1074/jbc.M401292200. PMID:15044490.
Lacy DB، Wigelsworth DJ، Scobie HM، وآخرون (2004). "Crystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor". Proc. Natl. Acad. Sci. U.S.A. ج. 101 ع. 17: 6367–72. DOI:10.1073/pnas.0401506101. PMC:404051. PMID:15079089.
Colland F، Jacq X، Trouplin V، وآخرون (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. ج. 14 ع. 7: 1324–32. DOI:10.1101/gr.2334104. PMC:442148. PMID:15231748.
Santelli E، Bankston LA، Leppla SH، Liddington RC (2004). "Crystal structure of a complex between anthrax toxin and its host cell receptor". Nature. ج. 430 ع. 7002: 905–8. DOI:10.1038/nature02763. PMID:15243628.
Lacy DB، Wigelsworth DJ، Melnyk RA، وآخرون (2004). "Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation". Proc. Natl. Acad. Sci. U.S.A. ج. 101 ع. 36: 13147–51. DOI:10.1073/pnas.0405405101. PMC:516539. PMID:15326297.
Abrami L، Lindsay M، Parton RG، وآخرون (2004). "Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway". J. Cell Biol. ج. 166 ع. 5: 645–51. DOI:10.1083/jcb.200312072. PMC:2172425. PMID:15337774.
Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
Lee JY، Tsai YM، Chao SC، Tu YF (2005). "Capillary morphogenesis gene-2 mutation in infantile systemic hyalinosis: ultrastructural study and mutation analysis in a Taiwanese infant". Clin. Exp. Dermatol. ج. 30 ع. 2: 176–9. DOI:10.1111/j.1365-2230.2004.01698.x. PMID:15725249.
Abrami L، Leppla SH، van der Goot FG (2006). "Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis". J. Cell Biol. ج. 172 ع. 2: 309–20. DOI:10.1083/jcb.200507067. PMC:2063559. PMID:16401723.
Gao M، Schulten K (2007). "Onset of anthrax toxin pore formation". Biophys. J. ج. 90 ع. 9: 3267–79. DOI:10.1529/biophysj.105.079376. PMC:1432108. PMID:16473908.
Wei W، Lu Q، Chaudry GJ، وآخرون (2006). "The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin". Cell. ج. 124 ع. 6: 1141–54. DOI:10.1016/j.cell.2005.12.045. PMID:16564009.

هذه بذرة مقالة عن جين على كروموسوم 4 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[pmid11683410-1] Bell SE، Mavila A، Salazar R، Bayless KJ، Kanagala S، Maxwell SA، Davis GE (أكتوبر 2001). "Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling". J Cell Sci. ج. 114 ع. Pt 15: 2755–73. PMID:11683410.

[entrez-2] "Entrez Gene: ANTXR2 anthrax toxin receptor 2". مؤرشف من الأصل في 2010-03-07.

[pmid12700348-3] Scobie HM، Rainey GJ، Bradley KA، Young JA (أبريل 2003). "Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor". Proc Natl Acad Sci U S A. ج. 100 ع. 9: 5170–4. DOI:10.1073/pnas.0431098100. PMC:154317. PMID:12700348.

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