MAPRE1

An Error has occured retrieving Wikidata item for infobox MAPRE1‏ (Microtubule associated protein RP/EB family member 1) هوَ بروتين يُشَفر بواسطة جين MAPRE1 في الإنسان.^[1]^[2]^[3]^[4]

الوظيفة

الأهمية السريرية

المراجع

^ Berrueta L، Kraeft SK، Tirnauer JS، Schuyler SC، Chen LB، Hill DE، Pellman D، Bierer BE (سبتمبر 1998). "The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules". Proc. Natl. Acad. Sci. USA. ج. 95 ع. 18: 10596–601. Bibcode:1998PNAS...9510596B. DOI:10.1073/pnas.95.18.10596. PMC:27940. PMID:9724749.
^ Nakamura M، Zhou XZ، Lu KP (يوليو 2001). "Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization". Curr. Biol. ج. 11 ع. 13: 1062–7. DOI:10.1016/S0960-9822(01)00297-4. PMID:11470413.
^ "Entrez Gene: MAPRE1 microtubule-associated protein, RP/EB family, member 1". مؤرشف من الأصل في 2010-12-05.
^ Su LK، Burrell M، Hill DE، Gyuris J، Brent R، Wiltshire R، Trent J، Vogelstein B، Kinzler KW (أغسطس 1995). "APC binds to the novel protein EB1". Cancer Res. ج. 55 ع. 14: 2972–7. PMID:7606712.

قراءة متعمقة

Tirnauer JS، Bierer BE (2000). "EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability". J. Cell Biol. ج. 149 ع. 4: 761–6. DOI:10.1083/jcb.149.4.761. PMC:2174556. PMID:10811817.
Morrison EE، Wardleworth BN، Askham JM، Markham AF، Meredith DM (1999). "EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle". Oncogene. ج. 17 ع. 26: 3471–7. DOI:10.1038/sj.onc.1202247. PMID:10030671.
Juwana JP، Henderikx P، Mischo A، Wadle A، Fadle N، Gerlach K، Arends JW، Hoogenboom H، Pfreundschuh M، Renner C (1999). "EB/RP gene family encodes tubulin binding proteins". Int. J. Cancer. ج. 81 ع. 2: 275–84. DOI:10.1002/(SICI)1097-0215(19990412)81:2<275::AID-IJC18>3.0.CO;2-Z. PMID:10188731.
Berrueta L، Tirnauer JS، Schuyler SC، Pellman D، Bierer BE (1999). "The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain". Curr. Biol. ج. 9 ع. 8: 425–8. DOI:10.1016/S0960-9822(99)80190-0. PMID:10226031.
Nakagawa H، Koyama K، Murata Y، Morito M، Akiyama T، Nakamura Y (2000). "EB3, a novel member of the EB1 family preferentially expressed in the central nervous system, binds to a CNS-specific APC homologue". Oncogene. ج. 19 ع. 2: 210–6. DOI:10.1038/sj.onc.1203308. PMID:10644998.
Askham JM، Moncur P، Markham AF، Morrison EE (2000). "Regulation and function of the interaction between the APC tumour suppressor protein and EB1". Oncogene. ج. 19 ع. 15: 1950–8. DOI:10.1038/sj.onc.1203498. PMID:10773885.
Mimori-Kiyosue Y، Shiina N، Tsukita S (2000). "The dynamic behavior of the APC-binding protein EB1 on the distal ends of microtubules". Curr. Biol. ج. 10 ع. 14: 865–8. DOI:10.1016/S0960-9822(00)00600-X. PMID:10899006.
Zhou XZ، Lu KP (2001). "The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor". Cell. ج. 107 ع. 3: 347–59. DOI:10.1016/S0092-8674(01)00538-4. PMID:11701125.
Nakamura M، Zhou XZ، Kishi S، Lu KP (2002). "Involvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindle". FEBS Lett. ج. 514 ع. 2–3: 193–8. DOI:10.1016/S0014-5793(02)02363-3. PMID:11943150.
Askham JM، Vaughan KT، Goodson HV، Morrison EE (2003). "Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome". Mol. Biol. Cell. ج. 13 ع. 10: 3627–45. DOI:10.1091/mbc.E02-01-0061. PMC:129971. PMID:12388762.
Tirnauer JS، Canman JC، Salmon ED، Mitchison TJ (2003). "EB1 targets to kinetochores with attached, polymerizing microtubules". Mol. Biol. Cell. ج. 13 ع. 12: 4308–16. DOI:10.1091/mbc.E02-04-0236. PMC:138635. PMID:12475954.
Ligon LA، Shelly SS، Tokito M، Holzbaur EL (2003). "The microtubule plus-end proteins EB1 and dynactin have differential effects on microtubule polymerization". Mol. Biol. Cell. ج. 14 ع. 4: 1405–17. DOI:10.1091/mbc.E02-03-0155. PMC:153110. PMID:12686597.
Hayashi I، Ikura M (2003). "Crystal structure of the amino-terminal microtubule-binding domain of end-binding protein 1 (EB1)". J. Biol. Chem. ج. 278 ع. 38: 36430–4. DOI:10.1074/jbc.M305773200. PMID:12857735.
Bu W، Su LK (2004). "Characterization of functional domains of human EB1 family proteins". J. Biol. Chem. ج. 278 ع. 50: 49721–31. DOI:10.1074/jbc.M306194200. PMID:14514668.
Bieling P، Laan L، Schek H، Munteanu EL، Sandblad L، Dogterom M، Brunner D، Surrey T (2007). "Reconstitution of a microtubule plus-end tracking system in vitro". Nature. ج. 450 ع. 7172: 1100–5. Bibcode:2007Natur.450.1100B. DOI:10.1038/nature06386. PMID:18059460.
Maurer SP، Fourniol FJ، Bohner G، Moores CA، Surrey T (2012). "EBs recognize a nucleotide-dependent structural cap at growing microtubule ends". Cell. ج. 149 ع. 2: 371–82. DOI:10.1016/j.cell.2012.02.049. PMC:3368265. PMID:22500803.
Nakamura S، Grigoriev I، Nogi T، Hamaji T، Cassimeris L، Mimori-Kiyosue Y (2012). "Dissecting the nanoscale distributions and functions of microtubule-end-binding proteins EB1 and ch-TOG in interphase HeLa cells". PLoS ONE. ج. 7 ع. 12: e51442. Bibcode:2012PLoSO...751442N. DOI:10.1371/journal.pone.0051442. PMC:3520847. PMID:23251535.
Zanic M، Widlund PO، Hyman AA، Howard J (2013). "Synergy between XMAP215 and EB1 increases microtubule growth rates to physiological levels". Nat. Cell Biol. ج. 15 ع. 6: 688–93. DOI:10.1038/ncb2744. PMID:23666085.
Jie، Chen (2014). "Phosphoregulation of the dimerization and functions of end-binding protein 1". Protein & Cell. ج. 5 ع. 10: 795–799. DOI:10.1007/s13238-014-0081-9. PMC:4180461. PMID:25048701.

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

[pmid9724749-1] Berrueta L، Kraeft SK، Tirnauer JS، Schuyler SC، Chen LB، Hill DE، Pellman D، Bierer BE (سبتمبر 1998). "The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules". Proc. Natl. Acad. Sci. USA. ج. 95 ع. 18: 10596–601. Bibcode:1998PNAS...9510596B. DOI:10.1073/pnas.95.18.10596. PMC:27940. PMID:9724749.

[pmid11470413-2] Nakamura M، Zhou XZ، Lu KP (يوليو 2001). "Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization". Curr. Biol. ج. 11 ع. 13: 1062–7. DOI:10.1016/S0960-9822(01)00297-4. PMID:11470413.

[entrez-3] "Entrez Gene: MAPRE1 microtubule-associated protein, RP/EB family, member 1". مؤرشف من الأصل في 2010-12-05.

[pmid7606712-4] Su LK، Burrell M، Hill DE، Gyuris J، Brent R، Wiltshire R، Trent J، Vogelstein B، Kinzler KW (أغسطس 1995). "APC binds to the novel protein EB1". Cancer Res. ج. 55 ع. 14: 2972–7. PMID:7606712.

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