FLII

An Error has occured retrieving Wikidata item for infobox FLII‏ (FLII, actin remodeling protein) هوَ بروتين يُشَفر بواسطة جين FLII في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ Chen KS، Gunaratne PH، Hoheisel JD، Young IG، Miklos GL، Greenberg F، Shaffer LG، Campbell HD، Lupski JR (فبراير 1995). "The human homologue of the Drosophila melanogaster flightless-I gene (flil) maps within the Smith-Magenis microdeletion critical region in 17p11.2". Am J Hum Genet. ج. 56 ع. 1: 175–82. PMC:1801336. PMID:7825574.
^ Ghoshdastider U, Popp D, Burtnick LD, Robinson RC (2013). "The expanding superfamily of gelsolin homology domain proteins". Cytoskeleton (Hoboken). ج. 70 ع. 11: 775–95. DOI:10.1002/cm.21149. PMID:24155256.
^ "Entrez Gene: FLII flightless I homolog (Drosophila)". مؤرشف من الأصل في 2010-12-05.

قراءة متعمقة

Campbell HD، Schimansky T، Claudianos C، وآخرون (1994). "The Drosophila melanogaster flightless-I gene involved in gastrulation and muscle degeneration encodes gelsolin-like and leucine-rich repeat domains and is conserved in Caenorhabditis elegans and humans". Proc. Natl. Acad. Sci. U.S.A. ج. 90 ع. 23: 11386–90. Bibcode:1993PNAS...9011386C. DOI:10.1073/pnas.90.23.11386. PMC:47987. PMID:8248259.
Campbell HD، Fountain S، Young IG، وآخرون (1997). "Genomic structure, evolution, and expression of human FLII, a gelsolin and leucine-rich-repeat family member: overlap with LLGL". Genomics. ج. 42 ع. 1: 46–54. DOI:10.1006/geno.1997.4709. PMID:9177775.
Liu YT، Yin HL (1998). "Identification of the binding partners for flightless I, A novel protein bridging the leucine-rich repeat and the gelsolin superfamilies". J. Biol. Chem. ج. 273 ع. 14: 7920–7. DOI:10.1074/jbc.273.14.7920. PMID:9525888.
Wilson SA، Brown EC، Kingsman AJ، Kingsman SM (1998). "TRIP: a novel double stranded RNA binding protein which interacts with the leucine rich repeat of flightless I." Nucleic Acids Res. ج. 26 ع. 15: 3460–7. DOI:10.1093/nar/26.15.3460. PMC:147727. PMID:9671805.
Fong KS، de Couet HG (1999). "Novel proteins interacting with the leucine-rich repeat domain of human flightless-I identified by the yeast two-hybrid system". Genomics. ج. 58 ع. 2: 146–57. DOI:10.1006/geno.1999.5817. PMID:10366446.
Davy DA، Campbell HD، Fountain S، وآخرون (2001). "The flightless I protein colocalizes with actin- and microtubule-based structures in motile Swiss 3T3 fibroblasts: evidence for the involvement of PI 3-kinase and Ras-related small GTPases". J. Cell Sci. ج. 114 ع. Pt 3: 549–62. PMID:11171324.
Campbell HD، Fountain S، McLennan IS، وآخرون (2002). "Fliih, a gelsolin-related cytoskeletal regulator essential for early mammalian embryonic development". Mol. Cell. Biol. ج. 22 ع. 10: 3518–26. DOI:10.1128/MCB.22.10.3518-3526.2002. PMC:133791. PMID:11971982.
Bi W، Yan J، Stankiewicz P، وآخرون (2002). "Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse". Genome Res. ج. 12 ع. 5: 713–28. DOI:10.1101/gr.73702. PMC:186594. PMID:11997338.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Gevaert K، Goethals M، Martens L، وآخرون (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. ج. 21 ع. 5: 566–9. DOI:10.1038/nbt810. PMID:12665801.
Lee YH، Campbell HD، Stallcup MR (2004). "Developmentally essential protein flightless I is a nuclear receptor coactivator with actin binding activity". Mol. Cell. Biol. ج. 24 ع. 5: 2103–17. DOI:10.1128/MCB.24.5.2103-2117.2004. PMC:350567. PMID:14966289.
Beausoleil SA، Jedrychowski M، Schwartz D، وآخرون (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. ج. 101 ع. 33: 12130–5. Bibcode:2004PNAS..10112130B. DOI:10.1073/pnas.0404720101. PMC:514446. PMID:15302935.
Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
Wang T، Chuang TH، Ronni T، وآخرون (2006). "Flightless I homolog negatively modulates the TLR pathway". J. Immunol. ج. 176 ع. 3: 1355–62. DOI:10.4049/jimmunol.176.3.1355. PMID:16424162.
Beausoleil SA، Villén J، Gerber SA، وآخرون (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. ج. 24 ع. 10: 1285–92. DOI:10.1038/nbt1240. PMID:16964243.
Olsen JV، Blagoev B، Gnad F، وآخرون (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. ج. 127 ع. 3: 635–48. DOI:10.1016/j.cell.2006.09.026. PMID:17081983.

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

[pmid7825574-1] Chen KS، Gunaratne PH، Hoheisel JD، Young IG، Miklos GL، Greenberg F، Shaffer LG، Campbell HD، Lupski JR (فبراير 1995). "The human homologue of the Drosophila melanogaster flightless-I gene (flil) maps within the Smith-Magenis microdeletion critical region in 17p11.2". Am J Hum Genet. ج. 56 ع. 1: 175–82. PMC:1801336. PMID:7825574.

[pmid24155256-2] Ghoshdastider U, Popp D, Burtnick LD, Robinson RC (2013). "The expanding superfamily of gelsolin homology domain proteins". Cytoskeleton (Hoboken). ج. 70 ع. 11: 775–95. DOI:10.1002/cm.21149. PMID:24155256.

[entrez-3] "Entrez Gene: FLII flightless I homolog (Drosophila)". مؤرشف من الأصل في 2010-12-05.

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