SPINT1
An Error has occured retrieving Wikidata item for infobox SPINT1 (Serine peptidase inhibitor, Kunitz type 1) هوَ بروتين يُشَفر بواسطة جين SPINT1 في الإنسان.[1]
الوظيفة
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
- ^ "Entrez Gene: SPINT1 serine peptidase inhibitor, Kunitz type 1". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
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- Shimomura T، Denda K، Kitamura A، وآخرون (1997). "Hepatocyte growth factor activator inhibitor, a novel Kunitz-type serine protease inhibitor". J. Biol. Chem. ج. 272 ع. 10: 6370–6. DOI:10.1074/jbc.272.10.6370. PMID:9045658.
- Yamada T، Tsujioka Y، Taguchi J، وآخرون (1998). "White matter astrocytes produce hepatocyte growth factor activator inhibitor in human brain tissues". Exp. Neurol. ج. 153 ع. 1: 60–4. DOI:10.1006/exnr.1998.6874. PMID:9743567.
- Kataoka H، Suganuma T، Shimomura T، وآخرون (1999). "Distribution of hepatocyte growth factor activator inhibitor type 1 (HAI-1) in human tissues. Cellular surface localization of HAI-1 in simple columnar epithelium and its modulated expression in injured and regenerative tissues". J. Histochem. Cytochem. ج. 47 ع. 5: 673–82. DOI:10.1177/002215549904700509. PMID:10219059.
- Lin CY، Anders J، Johnson M، Dickson RB (1999). "Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk". J. Biol. Chem. ج. 274 ع. 26: 18237–42. DOI:10.1074/jbc.274.26.18237. PMID:10373425.
- Shimomura T، Denda K، Kawaguchi T، وآخرون (2000). "Multiple sites of proteolytic cleavage to release soluble forms of hepatocyte growth factor activator inhibitor type 1 from a transmembrane form". J. Biochem. ج. 126 ع. 5: 821–8. DOI:10.1093/oxfordjournals.jbchem.a022522. PMID:10544273.
- Itoh H، Yamauchi M، Kataoka H، وآخرون (2000). "Genomic structure and chromosomal localization of the human hepatocyte growth factor activator inhibitor type 1 and 2 genes". Eur. J. Biochem. ج. 267 ع. 11: 3351–9. DOI:10.1046/j.1432-1327.2000.01368.x. PMID:10824123.
- Kataoka H، Shimomura T، Kawaguchi T، وآخرون (2001). "Hepatocyte growth factor activator inhibitor type 1 is a specific cell surface binding protein of hepatocyte growth factor activator (HGFA) and regulates HGFA activity in the pericellular microenvironment". J. Biol. Chem. ج. 275 ع. 51: 40453–62. DOI:10.1074/jbc.M006412200. PMID:11013244.
- Kataoka H، Meng JY، Itoh H، وآخرون (2001). "Localization of hepatocyte growth factor activator inhibitor type 1 in Langhans' cells of human placenta". Histochem. Cell Biol. ج. 114 ع. 6: 469–75. DOI:10.1007/s004180000228. PMID:11201608.
- Oberst M، Anders J، Xie B، وآخرون (2001). "Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo". Am. J. Pathol. ج. 158 ع. 4: 1301–11. DOI:10.1016/S0002-9440(10)64081-3. PMC:1891898. PMID:11290548.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Kirchhofer D، Peek M، Li W، وآخرون (2003). "Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1". J. Biol. Chem. ج. 278 ع. 38: 36341–9. DOI:10.1074/jbc.M304643200. PMID:12815039.
- Clark HF، Gurney AL، Abaya E، وآخرون (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. ج. 13 ع. 10: 2265–70. DOI:10.1101/gr.1293003. PMC:403697. PMID:12975309.
- Colland F، Jacq X، Trouplin V، وآخرون (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. ج. 14 ع. 7: 1324–32. DOI:10.1101/gr.2334104. PMC:442148. PMID:15231748.
- Zhang Z، Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. ج. 13 ع. 10: 2819–24. DOI:10.1110/ps.04682504. PMC:2286551. PMID:15340161.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Shia S، Stamos J، Kirchhofer D، وآخرون (2005). "Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B". J. Mol. Biol. ج. 346 ع. 5: 1335–49. DOI:10.1016/j.jmb.2004.12.048. PMID:15713485.
- Fan B، Wu TD، Li W، Kirchhofer D (2005). "Identification of hepatocyte growth factor activator inhibitor-1B as a potential physiological inhibitor of prostasin". J. Biol. Chem. ج. 280 ع. 41: 34513–20. DOI:10.1074/jbc.M502119200. PMID:16103126.
- Rual JF، Venkatesan K، Hao T، وآخرون (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. ج. 437 ع. 7062: 1173–8. DOI:10.1038/nature04209. PMID:16189514.