WNT7A

An Error has occured retrieving Wikidata item for infobox WNT7A‏ (Wnt family member 7A) هوَ بروتين يُشَفر بواسطة جين WNT7A في الإنسان.^[1]^[2]^[3]

الوظيفة

الأهمية السريرية

المراجع

^ "Entrez Gene: WNT7A wingless-type MMTV integration site family, member 7A". مؤرشف من الأصل في 2010-12-05.
^ Bui TD، Lako M، Lejeune S، Curtis AR، Strachan T، Lindsay S، Harris AL (يونيو 1997). "Isolation of a full-length human WNT7A gene implicated in limb development and cell transformation, and mapping to chromosome 3p25". Gene. ج. 189 ع. 1: 25–9. DOI:10.1016/S0378-1119(96)00808-6. PMID:9161407.
^ Ikegawa S، Kumano Y، Okui K، Fujiwara T، Takahashi E، Nakamura Y (ديسمبر 1996). "Isolation, characterization and chromosomal assignment of the human WNT7A gene". Cytogenet Cell Genet. ج. 74 ع. 1–2: 149–52. DOI:10.1159/000134404. PMID:8893824.

قراءة متعمقة

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Parr BA، McMahon AP (1998). "Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a". Nature. ج. 395 ع. 6703: 707–10. DOI:10.1038/27221. PMID:9790192.
Calvo R، West J، Franklin W، وآخرون (2001). "Altered HOX and WNT7A expression in human lung cancer". Proc. Natl. Acad. Sci. U.S.A. ج. 97 ع. 23: 12776–81. DOI:10.1073/pnas.97.23.12776. PMC:18840. PMID:11070089.
Li S، Chiang TC، Davis GR، وآخرون (2001). "Decreased expression of Wnt7a mRNA is inversely associated with the expression of estrogen receptor-alpha in human uterine leiomyoma". J. Clin. Endocrinol. Metab. ج. 86 ع. 1: 454–7. DOI:10.1210/jc.86.1.454. PMID:11232041.
Couse JF، Dixon D، Yates M، وآخرون (2002). "Estrogen receptor-alpha knockout mice exhibit resistance to the developmental effects of neonatal diethylstilbestrol exposure on the female reproductive tract". Dev. Biol. ج. 238 ع. 2: 224–38. DOI:10.1006/dbio.2001.0413. PMID:11784006.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Caricasole A، Ferraro T، Iacovelli L، وآخرون (2003). "Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins". J. Biol. Chem. ج. 278 ع. 39: 37024–31. DOI:10.1074/jbc.M300191200. PMID:12857724.
Tuli R، Tuli S، Nandi S، وآخرون (2003). "Transforming growth factor-beta-mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogen-activated protein kinase and Wnt signaling cross-talk". J. Biol. Chem. ج. 278 ع. 42: 41227–36. DOI:10.1074/jbc.M305312200. PMID:12893825.
Ohira T، Gemmill RM، Ferguson K، وآخرون (2003). "WNT7a induces E-cadherin in lung cancer cells". Proc. Natl. Acad. Sci. U.S.A. ج. 100 ع. 18: 10429–34. DOI:10.1073/pnas.1734137100. PMC:193578. PMID:12937339.
Timmreck LS، Pan HA، Reindollar RH، Gray MR (2004). "WNT7A mutations in patients with Müllerian duct abnormalities". Journal of pediatric and adolescent gynecology. ج. 16 ع. 4: 217–21. DOI:10.1016/S1083-3188(03)00124-4. PMID:14550385.
Hwang SG، Ryu JH، Kim IC، وآخرون (2004). "Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms". J. Biol. Chem. ج. 279 ع. 25: 26597–604. DOI:10.1074/jbc.M401401200. PMID:15082716.
Winn RA، Marek L، Han SY، وآخرون (2005). "Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation". J. Biol. Chem. ج. 280 ع. 20: 19625–34. DOI:10.1074/jbc.M409392200. PMID:15705594.
Lyu J، Joo CK (2005). "Wnt-7a up-regulates matrix metalloproteinase-12 expression and promotes cell proliferation in corneal epithelial cells during wound healing". J. Biol. Chem. ج. 280 ع. 22: 21653–60. DOI:10.1074/jbc.M500374200. PMID:15802269.
Woods CG، Stricker S، Seemann P، وآخرون (2006). "Mutations in WNT7A Cause a Range of Limb Malformations, Including Fuhrmann Syndrome and Al-Awadi/Raas-Rothschild/Schinzel Phocomelia Syndrome". Am. J. Hum. Genet. ج. 79 ع. 2: 402–8. DOI:10.1086/506332. PMC:1559483. PMID:16826533.
Winn RA، Van Scoyk M، Hammond M، وآخرون (2006). "Antitumorigenic effect of Wnt 7a and Fzd 9 in non-small cell lung cancer cells is mediated through ERK-5-dependent activation of peroxisome proliferator-activated receptor gamma". J. Biol. Chem. ج. 281 ع. 37: 26943–50. DOI:10.1074/jbc.M604145200. PMID:16835228.
Lindberg D، Akerström G، Westin G (2007). "Mutational analyses of WNT7A and HDAC11 as candidate tumour suppressor genes in sporadic malignant pancreatic endocrine tumours". Clin. Endocrinol. ج. 66 ع. 1: 110–4. DOI:10.1111/j.1365-2265.2006.02694.x. PMID:17201809.
Thrasivoulou C، Millar M، Ahmed A (2013). "Activation of intracellular calcium by multiple Wnt ligands and translocation of ß-catenin into the nucleus: a convergent model of Wnt/Ca2+ and Wnt/ß-catenin pathways". J. Biol. Chem. ج. 288 ع. 50: 35651–35659. DOI:10.1074/jbc.M112.437913. PMC:3861617. PMID:24158438. {{استشهاد بدورية محكمة}}: الوسيط غير المعروف |last-author-amp= تم تجاهله يقترح استخدام |name-list-style= (مساعدة)

هذه بذرة مقالة عن جين على كروموسوم 3 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[entrez-1] "Entrez Gene: WNT7A wingless-type MMTV integration site family, member 7A". مؤرشف من الأصل في 2010-12-05.

[pmid9161407-2] Bui TD، Lako M، Lejeune S، Curtis AR، Strachan T، Lindsay S، Harris AL (يونيو 1997). "Isolation of a full-length human WNT7A gene implicated in limb development and cell transformation, and mapping to chromosome 3p25". Gene. ج. 189 ع. 1: 25–9. DOI:10.1016/S0378-1119(96)00808-6. PMID:9161407.

[pmid8893824-3] Ikegawa S، Kumano Y، Okui K، Fujiwara T، Takahashi E، Nakamura Y (ديسمبر 1996). "Isolation, characterization and chromosomal assignment of the human WNT7A gene". Cytogenet Cell Genet. ج. 74 ع. 1–2: 149–52. DOI:10.1159/000134404. PMID:8893824.

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