BCAR3
An Error has occured retrieving Wikidata item for infobox BCAR3 (BCAR3, NSP family adaptor protein) هوَ بروتين يُشَفر بواسطة جين BCAR3 في الإنسان.[1][2]
الوظيفة
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
- ^ van Agthoven T، van Agthoven TL، Dekker A، van der Spek PJ، Vreede L، Dorssers LC (يوليو 1998). "Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells". EMBO J. ج. 17 ع. 10: 2799–808. DOI:10.1093/emboj/17.10.2799. PMC:1170620. PMID:9582273.
- ^ "Entrez Gene: BCAR3 breast cancer anti-estrogen resistance 3". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Dorssers LC، van Agthoven T (1997). "Genetic mechanisms of estrogen-independence in breast cancer". Pathol. Res. Pract. ج. 192 ع. 7: 743–51. DOI:10.1016/S0344-0338(96)80096-3. PMID:8880875.
- Johnston SR (1998). "Acquired tamoxifen resistance in human breast cancer--potential mechanisms and clinical implications". Anticancer Drugs. ج. 8 ع. 10: 911–30. DOI:10.1097/00001813-199711000-00002. PMID:9436634.
- Lu Y، Brush J، Stewart TA (1999). "NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway". J. Biol. Chem. ج. 274 ع. 15: 10047–52. DOI:10.1074/jbc.274.15.10047. PMID:10187783.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
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- Clark HF، Gurney AL، Abaya E، وآخرون (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. ج. 13 ع. 10: 2265–70. DOI:10.1101/gr.1293003. PMC:403697. PMID:12975309.
- Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Dorssers LC، van Agthoven T، Brinkman A، وآخرون (2006). "Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway". Breast Cancer Res. ج. 7 ع. 1: R82–92. DOI:10.1186/bcr954. PMC:1064102. PMID:15642172.
- Felekkis KN، Narsimhan RP، Near R، وآخرون (2005). "AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner". Mol. Cancer Res. ج. 3 ع. 1: 32–41. PMID:15671247.
- Gregory SG، Barlow KF، McLay KE، وآخرون (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. ج. 441 ع. 7091: 315–21. DOI:10.1038/nature04727. PMID:16710414.
- Beausoleil SA، Villén J، Gerber SA، وآخرون (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. ج. 24 ع. 10: 1285–92. DOI:10.1038/nbt1240. PMID:16964243.
- Olsen JV، Blagoev B، Gnad F، وآخرون (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. ج. 127 ع. 3: 635–48. DOI:10.1016/j.cell.2006.09.026. PMID:17081983.
- Vervoort VS، Roselli S، Oshima RG، Pasquale EB (2007). "Splice variants and expression patterns of SHEP1, BCAR3 and NSP1, a gene family involved in integrin and receptor tyrosine kinase signaling". Gene. ج. 391 ع. 1–2: 161–70. DOI:10.1016/j.gene.2006.12.016. PMC:1876674. PMID:17270363.
- Ewing RM، Chu P، Elisma F، وآخرون (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. ج. 3 ع. 1: 89. DOI:10.1038/msb4100134. PMC:1847948. PMID:17353931.
- Near RI، Zhang Y، Makkinje A، وآخرون (2007). "AND-34/BCAR3 differs from other NSP homologs in induction of anti-estrogen resistance, cyclin D1 promoter activation and altered breast cancer cell morphology". J. Cell. Physiol. ج. 212 ع. 3: 655–65. DOI:10.1002/jcp.21059. PMC:2640322. PMID:17427198.
- Schrecengost RS، Riggins RB، Thomas KS، وآخرون (2007). "Breast cancer antiestrogen resistance-3 expression regulates breast cancer cell migration through promotion of p130Cas membrane localization and membrane ruffling". Cancer Res. ج. 67 ع. 13: 6174–82. DOI:10.1158/0008-5472.CAN-06-3455. PMC:4109708. PMID:17616674.