قالب:PBB/672

Breast cancer 1, early onset
ملف:Protein BRCA1 PDB 1jm7.png PDB rendering based on 1jm7.
التراكيب المتوفرة بنك بيانات البروتين بحث أورثولوغ: PDBe, RCSB قائمة رموز معرفات بنك بيانات البروتين 1JM7, 1JNX, 1N5O, 1OQA, 1T15, 1T29, 1T2U, 1T2V, 1Y98, 2ING, 3COJ, 3K0H, 3K0K, 3K15, 3K16, 3PXA, 3PXB, 3PXC, 3PXD, 3PXE, 4IFI, 4IGK, 4JLU, 4OFB
المعرفات
الرمز، (أو الرموز)	BRCA1; BRCAI; BRCC1; BROVCA1; FANCS; IRIS; PNCA4; PPP1R53; PSCP; RNF53
معرفات خارجية	OMIM: 113705 MGI: 104537 هومولوجين: 5276 مختبر علم الأحياء الجزيئي الأوروبي الكيميائي: 5990 بطاقات الجينات: BRCA1 Gene
علم الوجود الجيني الوظيفة الجزيئية • DNA binding • damaged DNA binding • transcription coactivator activity • RNA binding • ubiquitin-protein transferase activity • protein binding • zinc ion binding • tubulin binding • ligase activity • enzyme binding • ubiquitin protein ligase binding • transcription regulatory region DNA binding • androgen receptor binding المكونات الخلوية • ubiquitin ligase complex • condensed nuclear chromosome • nucleus • nucleoplasm • chromosome • cytoplasm • plasma membrane • gamma-tubulin ring complex • ribonucleoprotein complex • BRCA1-BARD1 complex • protein complex • BRCA1-A complex العملية الإحيائية • double-strand break repair via homologous recombination • DNA replication • DNA repair • postreplication repair • double-strand break repair • regulation of gene expression by genetic imprinting • transcription, DNA-templated • regulation of transcription from RNA polymerase II promoter • regulation of transcription from RNA polymerase III promoter • fatty acid biosynthetic process • apoptotic process • cellular response to DNA damage stimulus • DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator • chromosome segregation • centrosome cycle • intrinsic apoptotic signaling pathway in response to DNA damage • dosage compensation by inactivation of X chromosome • response to ionizing radiation • positive regulation of vascular endothelial growth factor production • positive regulation of gene expression • protein ubiquitination • protein sumoylation • androgen receptor signaling pathway • positive regulation of protein ubiquitination • G2 DNA damage checkpoint • negative regulation of intracellular estrogen receptor signaling pathway • positive regulation of histone acetylation • negative regulation of histone acetylation • regulation of cell proliferation • regulation of apoptotic process • chordate embryonic development • response to estrogen • post-translational protein modification • regulation of DNA methylation • cellular protein metabolic process • negative regulation of fatty acid biosynthetic process • positive regulation of DNA repair • positive regulation of angiogenesis • negative regulation of transcription, DNA-templated • positive regulation of transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter • negative regulation of centriole replication • positive regulation of histone H3-K4 methylation • negative regulation of histone H3-K4 methylation • negative regulation of histone H3-K9 methylation • positive regulation of histone H3-K9 methylation • protein autoubiquitination • positive regulation of histone H4-K20 methylation • positive regulation of cell cycle arrest • cellular response to tumor necrosis factor • cellular response to indole-3-methanol • protein K6-linked ubiquitination • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • negative regulation of reactive oxygen species metabolic process • positive regulation of histone H3-K9 acetylation • positive regulation of histone H4-K16 acetylation المصادر: Amigo / QuickGO
نمط التعبير عن الحمض النووي الريبوزي
ملف:PBB GE BRCA1 204531 s at.png
ملف:PBB GE BRCA1 211851 x at.png
مصادر أخرى عن بيانات أنماط التعبير
التقويمات
الأنواع	الإنسان	الفأر
أنتريه	672	12189
انسمبل	ENSG00000012048	ENSMUSG00000017146
يونيبروت	P38398	P48754
قاعدة بيانات مرجعية (مرسال ر.ن.ا)	NM_007294	NM_009764
قاعدة بيانات مرجعية (بروتين)	NP_009225	NP_033894
الموقع (قاعدة بيانات UCSC)	Chr 17: 43.04 – 43.13 Mb	Chr 11: 101.49 – 101.55 Mb
بحث ببمد	[1]	[2]