عبد العزيز: بوت: تصنيف القالب

2018-11-21T17:57:27Z

بوت: تصنيف القالب

صفحة جديدة

{{GNF_Protein_box
| Name = Tumor necrosis factor
| image = TNFa_Crystal_Structure.rsh.png
| image_source = [[بنك بيانات البروتينات]] rendering based on 1TNF.
| PDB = {{PDB2|1A8M}}, {{PDB2|1TNF}}, {{PDB2|2AZ5}}, {{PDB2|2E7A}}, {{PDB2|2TUN}}, {{PDB2|2ZJC}}, {{PDB2|2ZPX}}, {{PDB2|3ALQ}}, {{PDB2|3IT8}}, {{PDB2|3L9J}}, {{PDB2|3WD5}}, {{PDB2|4G3Y}}, {{PDB2|4TSV}}, {{PDB2|4TWT}}, {{PDB2|5TSW}}
| HGNCid = 11892
| MGIid = 104798
| Symbol = TNF
| AltSymbols =; DIF; TNF-alpha; TNFA; TNFSF2
| IUPHAR =
| ChEMBL = 1825
| OMIM = 191160
| ECnumber =
| Homologene = 496
| GeneAtlas_image1 = PBB_GE_TNF_207113_s_at.png

| GeneAtlas_image2 =
| GeneAtlas_image3 =
| Protein_domain_image =
| Function = {{GNF GO|id=GO:0002020 |text = protease binding}} {{GNF GO|id=GO:0005125 |text = cytokine activity}} {{GNF GO|id=GO:0005164 |text = tumor necrosis factor receptor binding}} {{GNF GO|id=GO:0005515 |text = protein binding}} {{GNF GO|id=GO:0042802 |text = identical protein binding}} {{GNF GO|id=GO:0044212 |text = transcription regulatory region DNA binding}}
| Component = {{GNF GO|id=GO:0001891 |text = phagocytic cup}} {{GNF GO|id=GO:0005576 |text = extracellular region}} {{GNF GO|id=GO:0005615 |text = extracellular space}} {{GNF GO|id=GO:0005886 |text = plasma membrane}} {{GNF GO|id=GO:0005887 |text = integral component of plasma membrane}} {{GNF GO|id=GO:0009897 |text = external side of plasma membrane}} {{GNF GO|id=GO:0009986 |text = cell surface}} {{GNF GO|id=GO:0045121 |text = membrane raft}} {{GNF GO|id=GO:0055037 |text = recycling endosome}}
| Process = {{GNF GO|id=GO:0000060 |text = protein import into nucleus, translocation}} {{GNF GO|id=GO:0000122 |text = negative regulation of transcription from RNA polymerase II promoter}} {{GNF GO|id=GO:0000165 |text = MAPK cascade}} {{GNF GO|id=GO:0000185 |text = activation of MAPKKK activity}} {{GNF GO|id=GO:0000187 |text = activation of MAPK activity}} {{GNF GO|id=GO:0001819 |text = positive regulation of cytokine production}} {{GNF GO|id=GO:0001934 |text = positive regulation of protein phosphorylation}} {{GNF GO|id=GO:0002439 |text = chronic inflammatory response to antigenic stimulus}} {{GNF GO|id=GO:0002740 |text = negative regulation of cytokine secretion involved in immune response}} {{GNF GO|id=GO:0002876 |text = positive regulation of chronic inflammatory response to antigenic stimulus}} {{GNF GO|id=GO:0002925 |text = positive regulation of humoral immune response mediated by circulating immunoglobulin}} {{GNF GO|id=GO:0006006 |text = glucose metabolic process}} {{GNF GO|id=GO:0006919 |text = activation of cysteine-type endopeptidase activity involved in apoptotic process}} {{GNF GO|id=GO:0006927 |text = transformed cell apoptotic process}} {{GNF GO|id=GO:0006954 |text = inflammatory response}} {{GNF GO|id=GO:0006959 |text = humoral immune response}} {{GNF GO|id=GO:0007166 |text = cell surface receptor signaling pathway}} {{GNF GO|id=GO:0007254 |text = JNK cascade}} {{GNF GO|id=GO:0008625 |text = extrinsic apoptotic signaling pathway via death domain receptors}} {{GNF GO|id=GO:0008630 |text = intrinsic apoptotic signaling pathway in response to DNA damage}} {{GNF GO|id=GO:0009615 |text = response to virus}} {{GNF GO|id=GO:0009651 |text = response to salt stress}} {{GNF GO|id=GO:0010628 |text = positive regulation of gene expression}} {{GNF GO|id=GO:0010629 |text = negative regulation of gene expression}} {{GNF GO|id=GO:0010693 |text = negative regulation of alkaline phosphatase activity}} {{GNF GO|id=GO:0010888 |text = negative regulation of lipid storage}} {{GNF GO|id=GO:0030198 |text = extracellular matrix organization}} {{GNF GO|id=GO:0030316 |text = osteoclast differentiation}} {{GNF GO|id=GO:0030730 |text = sequestering of triglyceride}} {{GNF GO|id=GO:0031334 |text = positive regulation of protein complex assembly}} {{GNF GO|id=GO:0031622 |text = positive regulation of fever generation}} {{GNF GO|id=GO:0031663 |text = lipopolysaccharide-mediated signaling pathway}} {{GNF GO|id=GO:0032715 |text = negative regulation of interleukin-6 production}} {{GNF GO|id=GO:0032722 |text = positive regulation of chemokine production}} {{GNF GO|id=GO:0032729 |text = positive regulation of interferon-gamma production}} {{GNF GO|id=GO:0032755 |text = positive regulation of interleukin-6 production}} {{GNF GO|id=GO:0032757 |text = positive regulation of interleukin-8 production}} {{GNF GO|id=GO:0032800 |text = receptor biosynthetic process}} {{GNF GO|id=GO:0033138 |text = positive regulation of peptidyl-serine phosphorylation}} {{GNF GO|id=GO:0033209 |text = tumor necrosis factor-mediated signaling pathway}} {{GNF GO|id=GO:0034116 |text = positive regulation of heterotypic cell-cell adhesion}} {{GNF GO|id=GO:0042346 |text = positive regulation of NF-kappaB import into nucleus}} {{GNF GO|id=GO:0043065 |text = positive regulation of apoptotic process}} {{GNF GO|id=GO:0043068 |text = positive regulation of programmed cell death}} {{GNF GO|id=GO:0043122 |text = regulation of I-kappaB kinase/NF-kappaB signaling}} {{GNF GO|id=GO:0043123 |text = positive regulation of I-kappaB kinase/NF-kappaB signaling}} {{GNF GO|id=GO:0043242 |text = negative regulation of protein complex disassembly}} {{GNF GO|id=GO:0043243 |text = positive regulation of protein complex disassembly}} {{GNF GO|id=GO:0043280 |text = positive regulation of cysteine-type endopeptidase activity involved in apoptotic process}} {{GNF GO|id=GO:0043406 |text = positive regulation of MAP kinase activity}} {{GNF GO|id=GO:0043491 |text = protein kinase B signaling}} {{GNF GO|id=GO:0043507 |text = positive regulation of JUN kinase activity}} {{GNF GO|id=GO:0044130 |text = negative regulation of growth of symbiont in host}} {{GNF GO|id=GO:0045071 |text = negative regulation of viral genome replication}} {{GNF GO|id=GO:0045080 |text = positive regulation of chemokine biosynthetic process}} {{GNF GO|id=GO:0045416 |text = positive regulation of interleukin-8 biosynthetic process}} {{GNF GO|id=GO:0045429 |text = positive regulation of nitric oxide biosynthetic process}} {{GNF GO|id=GO:0045599 |text = negative regulation of fat cell differentiation}} {{GNF GO|id=GO:0045662 |text = negative regulation of myoblast differentiation}} {{GNF GO|id=GO:0045668 |text = negative regulation of osteoblast differentiation}} {{GNF GO|id=GO:0045672 |text = positive regulation of osteoclast differentiation}} {{GNF GO|id=GO:0045785 |text = positive regulation of cell adhesion}} {{GNF GO|id=GO:0045860 |text = positive regulation of protein kinase activity}} {{GNF GO|id=GO:0045892 |text = negative regulation of transcription, DNA-templated}} {{GNF GO|id=GO:0045893 |text = positive regulation of transcription, DNA-templated}} {{GNF GO|id=GO:0045944 |text = positive regulation of transcription from RNA polymerase II promoter}} {{GNF GO|id=GO:0045994 |text = positive regulation of translational initiation by iron}} {{GNF GO|id=GO:0046325 |text = negative regulation of glucose import}} {{GNF GO|id=GO:0048566 |text = embryonic digestive tract development}} {{GNF GO|id=GO:0048661 |text = positive regulation of smooth muscle cell proliferation}} {{GNF GO|id=GO:0050715 |text = positive regulation of cytokine secretion}} {{GNF GO|id=GO:0050766 |text = positive regulation of phagocytosis}} {{GNF GO|id=GO:0050796 |text = regulation of insulin secretion}} {{GNF GO|id=GO:0050830 |text = defense response to Gram-positive bacterium}} {{GNF GO|id=GO:0050901 |text = leukocyte tethering or rolling}} {{GNF GO|id=GO:0050995 |text = negative regulation of lipid catabolic process}} {{GNF GO|id=GO:0051023 |text = regulation of immunoglobulin secretion}} {{GNF GO|id=GO:0051044 |text = positive regulation of membrane protein ectodomain proteolysis}} {{GNF GO|id=GO:0051091 |text = positive regulation of sequence-specific DNA binding transcription factor activity}} {{GNF GO|id=GO:0051092 |text = positive regulation of NF-kappaB transcription factor activity}} {{GNF GO|id=GO:0051222 |text = positive regulation of protein transport}} {{GNF GO|id=GO:0051384 |text = response to glucocorticoid}} {{GNF GO|id=GO:0051533 |text = positive regulation of NFAT protein import into nucleus}} {{GNF GO|id=GO:0051798 |text = positive regulation of hair follicle development}} {{GNF GO|id=GO:0051897 |text = positive regulation of protein kinase B signaling}} {{GNF GO|id=GO:0060557 |text = positive regulation of vitamin D biosynthetic process}} {{GNF GO|id=GO:0060559 |text = positive regulation of calcidiol 1-monooxygenase activity}} {{GNF GO|id=GO:0060664 |text = epithelial cell proliferation involved in salivary gland morphogenesis}} {{GNF GO|id=GO:0060693 |text = regulation of branching involved in salivary gland morphogenesis}} {{GNF GO|id=GO:0061048 |text = negative regulation of branching involved in lung morphogenesis}} {{GNF GO|id=GO:0070374 |text = positive regulation of ERK1 and ERK2 cascade}} {{GNF GO|id=GO:0071230 |text = cellular response to amino acid stimulus}} {{GNF GO|id=GO:0071316 |text = cellular response to nicotine}} {{GNF GO|id=GO:0071407 |text = cellular response to organic cyclic compound}} {{GNF GO|id=GO:0071550 |text = death-inducing signaling complex assembly}} {{GNF GO|id=GO:0071677 |text = positive regulation of mononuclear cell migration}} {{GNF GO|id=GO:0071803 |text = positive regulation of podosome assembly}} {{GNF GO|id=GO:0097191 |text = extrinsic apoptotic signaling pathway}} {{GNF GO|id=GO:0097527 |text = necroptotic signaling pathway}} {{GNF GO|id=GO:2000010 |text = positive regulation of protein localization to cell surface}} {{GNF GO|id=GO:2000343 |text = positive regulation of chemokine (C-X-C motif) ligand 2 production}} {{GNF GO|id=GO:2001240 |text = negative regulation of extrinsic apoptotic signaling pathway in absence of ligand}}
| Hs_EntrezGene = 7124
| Hs_Ensembl = ENSG00000204490
| Hs_RefseqmRNA = NM_000594
| Hs_RefseqProtein = NP_000585
| Hs_GenLoc_db = hg38
| Hs_GenLoc_chr = 6
| Hs_GenLoc_start = 31575567
| Hs_GenLoc_end = 31578336
| Hs_Uniprot = P01375
| Mm_EntrezGene = 21926
| Mm_Ensembl = ENSMUSG00000024401
| Mm_RefseqmRNA = NM_001278601
| Mm_RefseqProtein = NP_001265530
| Mm_GenLoc_db = mm10
| Mm_GenLoc_chr = 17
| Mm_GenLoc_start = 35199381
| Mm_GenLoc_end = 35202007
| Mm_Uniprot = P06804
| path = PBB/7124
}}<noinclude>
[[تصنيف:قوالب بأسماء أجنبية]]
</noinclude>

قالب:PBB/7124 - تاريخ المراجعة

عبد العزيز: بوت: تصنيف القالب