عبد العزيز: بوت: تصنيف القالب

2018-11-21T17:57:19Z

بوت: تصنيف القالب

صفحة جديدة

{{GNF_Protein_box
| Name = Transforming growth factor, beta 1
| image = Protein_TGFB1_PDB_1kla.png
| image_source = [[بنك بيانات البروتينات]] rendering based on 1kla.
| PDB = {{PDB2|1KLA}}, {{PDB2|1KLC}}, {{PDB2|1KLD}}, {{PDB2|3KFD}}, {{PDB2|4KV5}}
| HGNCid = 11766
| MGIid = 98725
| Symbol = TGFB1
| AltSymbols =; CED; DPD1; LAP; TGFB; TGFbeta
| IUPHAR =
| ChEMBL = 1795178
| OMIM = 190180
| ECnumber =
| Homologene = 540
| GeneAtlas_image1 = PBB_GE_TGFB1_203085_s_at.png
| GeneAtlas_image2 = PBB_GE_TGFB1_203084_at.png

| GeneAtlas_image3 =
| Protein_domain_image =
| Function = {{GNF GO|id=GO:0001948 |text = glycoprotein binding}} {{GNF GO|id=GO:0003823 |text = antigen binding}} {{GNF GO|id=GO:0005114 |text = type II transforming growth factor beta receptor binding}} {{GNF GO|id=GO:0005125 |text = cytokine activity}} {{GNF GO|id=GO:0005515 |text = protein binding}} {{GNF GO|id=GO:0008083 |text = growth factor activity}} {{GNF GO|id=GO:0019899 |text = enzyme binding}} {{GNF GO|id=GO:0034713 |text = type I transforming growth factor beta receptor binding}} {{GNF GO|id=GO:0034714 |text = type III transforming growth factor beta receptor binding}} {{GNF GO|id=GO:0042803 |text = protein homodimerization activity}} {{GNF GO|id=GO:0046982 |text = protein heterodimerization activity}} {{GNF GO|id=GO:0047485 |text = protein N-terminus binding}}
| Component = {{GNF GO|id=GO:0005576 |text = extracellular region}} {{GNF GO|id=GO:0005578 |text = proteinaceous extracellular matrix}} {{GNF GO|id=GO:0005615 |text = extracellular space}} {{GNF GO|id=GO:0005634 |text = nucleus}} {{GNF GO|id=GO:0005737 |text = cytoplasm}} {{GNF GO|id=GO:0005796 |text = Golgi lumen}} {{GNF GO|id=GO:0005886 |text = plasma membrane}} {{GNF GO|id=GO:0005902 |text = microvillus}} {{GNF GO|id=GO:0009986 |text = cell surface}} {{GNF GO|id=GO:0030424 |text = axon}} {{GNF GO|id=GO:0031093 |text = platelet alpha granule lumen}} {{GNF GO|id=GO:0043025 |text = neuronal cell body}} {{GNF GO|id=GO:0072562 |text = blood microparticle}}
| Process = {{GNF GO|id=GO:0000060 |text = protein import into nucleus, translocation}} {{GNF GO|id=GO:0000122 |text = negative regulation of transcription from RNA polymerase II promoter}} {{GNF GO|id=GO:0000165 |text = MAPK cascade}} {{GNF GO|id=GO:0001657 |text = ureteric bud development}} {{GNF GO|id=GO:0001666 |text = response to hypoxia}} {{GNF GO|id=GO:0001837 |text = epithelial to mesenchymal transition}} {{GNF GO|id=GO:0001933 |text = negative regulation of protein phosphorylation}} {{GNF GO|id=GO:0001934 |text = positive regulation of protein phosphorylation}} {{GNF GO|id=GO:0002028 |text = regulation of sodium ion transport}} {{GNF GO|id=GO:0002062 |text = chondrocyte differentiation}} {{GNF GO|id=GO:0002244 |text = hematopoietic progenitor cell differentiation}} {{GNF GO|id=GO:0002248 |text = connective tissue replacement involved in inflammatory response wound healing}} {{GNF GO|id=GO:0002460 |text = adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains}} {{GNF GO|id=GO:0002513 |text = tolerance induction to self antigen}} {{GNF GO|id=GO:0002576 |text = platelet degranulation}} {{GNF GO|id=GO:0006468 |text = protein phosphorylation}} {{GNF GO|id=GO:0006611 |text = protein export from nucleus}} {{GNF GO|id=GO:0006754 |text = ATP biosynthetic process}} {{GNF GO|id=GO:0006796 |text = phosphate-containing compound metabolic process}} {{GNF GO|id=GO:0006874 |text = cellular calcium ion homeostasis}} {{GNF GO|id=GO:0006954 |text = inflammatory response}} {{GNF GO|id=GO:0007050 |text = cell cycle arrest}} {{GNF GO|id=GO:0007093 |text = mitotic cell cycle checkpoint}} {{GNF GO|id=GO:0007173 |text = epidermal growth factor receptor signaling pathway}} {{GNF GO|id=GO:0007179 |text = transforming growth factor beta receptor signaling pathway}} {{GNF GO|id=GO:0007182 |text = common-partner SMAD protein phosphorylation}} {{GNF GO|id=GO:0007183 |text = SMAD protein complex assembly}} {{GNF GO|id=GO:0007184 |text = SMAD protein import into nucleus}} {{GNF GO|id=GO:0007406 |text = negative regulation of neuroblast proliferation}} {{GNF GO|id=GO:0007435 |text = salivary gland morphogenesis}} {{GNF GO|id=GO:0007492 |text = endoderm development}} {{GNF GO|id=GO:0007565 |text = female pregnancy}} {{GNF GO|id=GO:0007568 |text = aging}} {{GNF GO|id=GO:0007596 |text = blood coagulation}} {{GNF GO|id=GO:0008156 |text = negative regulation of DNA replication}} {{GNF GO|id=GO:0008284 |text = positive regulation of cell proliferation}} {{GNF GO|id=GO:0008285 |text = negative regulation of cell proliferation}} {{GNF GO|id=GO:0008354 |text = germ cell migration}} {{GNF GO|id=GO:0009314 |text = response to radiation}} {{GNF GO|id=GO:0009611 |text = response to wounding}} {{GNF GO|id=GO:0009749 |text = response to glucose}} {{GNF GO|id=GO:0009817 |text = defense response to fungus, incompatible interaction}} {{GNF GO|id=GO:0010575 |text = positive regulation of vascular endothelial growth factor production}} {{GNF GO|id=GO:0010628 |text = positive regulation of gene expression}} {{GNF GO|id=GO:0010629 |text = negative regulation of gene expression}} {{GNF GO|id=GO:0010716 |text = negative regulation of extracellular matrix disassembly}} {{GNF GO|id=GO:0010718 |text = positive regulation of epithelial to mesenchymal transition}} {{GNF GO|id=GO:0010742 |text = macrophage derived foam cell differentiation}} {{GNF GO|id=GO:0010763 |text = positive regulation of fibroblast migration}} {{GNF GO|id=GO:0010800 |text = positive regulation of peptidyl-threonine phosphorylation}} {{GNF GO|id=GO:0010862 |text = positive regulation of pathway-restricted SMAD protein phosphorylation}} {{GNF GO|id=GO:0010936 |text = negative regulation of macrophage cytokine production}} {{GNF GO|id=GO:0014003 |text = oligodendrocyte development}} {{GNF GO|id=GO:0016049 |text = cell growth}} {{GNF GO|id=GO:0016202 |text = regulation of striated muscle tissue development}} {{GNF GO|id=GO:0017015 |text = regulation of transforming growth factor beta receptor signaling pathway}} {{GNF GO|id=GO:0019048 |text = modulation by virus of host morphology or physiology}} {{GNF GO|id=GO:0019049 |text = evasion or tolerance of host defenses by virus}} {{GNF GO|id=GO:0019058 |text = viral life cycle}} {{GNF GO|id=GO:0022408 |text = negative regulation of cell-cell adhesion}} {{GNF GO|id=GO:0030168 |text = platelet activation}} {{GNF GO|id=GO:0030198 |text = extracellular matrix organization}} {{GNF GO|id=GO:0030214 |text = hyaluronan catabolic process}} {{GNF GO|id=GO:0030279 |text = negative regulation of ossification}} {{GNF GO|id=GO:0030308 |text = negative regulation of cell growth}} {{GNF GO|id=GO:0030334 |text = regulation of cell migration}} {{GNF GO|id=GO:0030335 |text = positive regulation of cell migration}} {{GNF GO|id=GO:0030501 |text = positive regulation of bone mineralization}} {{GNF GO|id=GO:0030512 |text = negative regulation of transforming growth factor beta receptor signaling pathway}} {{GNF GO|id=GO:0031065 |text = positive regulation of histone deacetylation}} {{GNF GO|id=GO:0031100 |text = organ regeneration}} {{GNF GO|id=GO:0031334 |text = positive regulation of protein complex assembly}} {{GNF GO|id=GO:0031536 |text = positive regulation of exit from mitosis}} {{GNF GO|id=GO:0031663 |text = lipopolysaccharide-mediated signaling pathway}} {{GNF GO|id=GO:0032270 |text = positive regulation of cellular protein metabolic process}} {{GNF GO|id=GO:0032355 |text = response to estradiol}} {{GNF GO|id=GO:0032570 |text = response to progesterone}} {{GNF GO|id=GO:0032667 |text = regulation of interleukin-23 production}} {{GNF GO|id=GO:0032700 |text = negative regulation of interleukin-17 production}} {{GNF GO|id=GO:0032740 |text = positive regulation of interleukin-17 production}} {{GNF GO|id=GO:0032801 |text = receptor catabolic process}} {{GNF GO|id=GO:0032930 |text = positive regulation of superoxide anion generation}} {{GNF GO|id=GO:0032943 |text = mononuclear cell proliferation}} {{GNF GO|id=GO:0032967 |text = positive regulation of collagen biosynthetic process}} {{GNF GO|id=GO:0033138 |text = positive regulation of peptidyl-serine phosphorylation}} {{GNF GO|id=GO:0033280 |text = response to vitamin D}} {{GNF GO|id=GO:0034616 |text = response to laminar fluid shear stress}} {{GNF GO|id=GO:0035066 |text = positive regulation of histone acetylation}} {{GNF GO|id=GO:0035307 |text = positive regulation of protein dephosphorylation}} {{GNF GO|id=GO:0042130 |text = negative regulation of T cell proliferation}} {{GNF GO|id=GO:0042306 |text = regulation of protein import into nucleus}} {{GNF GO|id=GO:0042307 |text = positive regulation of protein import into nucleus}} {{GNF GO|id=GO:0042482 |text = positive regulation of odontogenesis}} {{GNF GO|id=GO:0042493 |text = response to drug}} {{GNF GO|id=GO:0042552 |text = myelination}} {{GNF GO|id=GO:0042981 |text = regulation of apoptotic process}} {{GNF GO|id=GO:0043011 |text = myeloid dendritic cell differentiation}} {{GNF GO|id=GO:0043029 |text = T cell homeostasis}} {{GNF GO|id=GO:0043065 |text = positive regulation of apoptotic process}} {{GNF GO|id=GO:0043406 |text = positive regulation of MAP kinase activity}} {{GNF GO|id=GO:0043491 |text = protein kinase B signaling}} {{GNF GO|id=GO:0043536 |text = positive regulation of blood vessel endothelial cell migration}} {{GNF GO|id=GO:0043537 |text = negative regulation of blood vessel endothelial cell migration}} {{GNF GO|id=GO:0043552 |text = positive regulation of phosphatidylinositol 3-kinase activity}} {{GNF GO|id=GO:0043932 |text = ossification involved in bone remodeling}} {{GNF GO|id=GO:0045066 |text = regulatory T cell differentiation}} {{GNF GO|id=GO:0045216 |text = cell-cell junction organization}} {{GNF GO|id=GO:0045596 |text = negative regulation of cell differentiation}} {{GNF GO|id=GO:0045599 |text = negative regulation of fat cell differentiation}} {{GNF GO|id=GO:0045662 |text = negative regulation of myoblast differentiation}} {{GNF GO|id=GO:0045786 |text = negative regulation of cell cycle}} {{GNF GO|id=GO:0045892 |text = negative regulation of transcription, DNA-templated}} {{GNF GO|id=GO:0045893 |text = positive regulation of transcription, DNA-templated}} {{GNF GO|id=GO:0045930 |text = negative regulation of mitotic cell cycle}} {{GNF GO|id=GO:0045944 |text = positive regulation of transcription from RNA polymerase II promoter}} {{GNF GO|id=GO:0046732 |text = active induction of host immune response by virus}} {{GNF GO|id=GO:0048298 |text = positive regulation of isotype switching to IgA isotypes}} {{GNF GO|id=GO:0048468 |text = cell development}} {{GNF GO|id=GO:0048535 |text = lymph node development}} {{GNF GO|id=GO:0048565 |text = digestive tract development}} {{GNF GO|id=GO:0048642 |text = negative regulation of skeletal muscle tissue development}} {{GNF GO|id=GO:0048839 |text = inner ear development}} {{GNF GO|id=GO:0050679 |text = positive regulation of epithelial cell proliferation}} {{GNF GO|id=GO:0050680 |text = negative regulation of epithelial cell proliferation}} {{GNF GO|id=GO:0050714 |text = positive regulation of protein secretion}} {{GNF GO|id=GO:0050765 |text = negative regulation of phagocytosis}} {{GNF GO|id=GO:0050921 |text = positive regulation of chemotaxis}} {{GNF GO|id=GO:0051092 |text = positive regulation of NF-kappaB transcription factor activity}} {{GNF GO|id=GO:0051098 |text = regulation of binding}} {{GNF GO|id=GO:0051101 |text = regulation of DNA binding}} {{GNF GO|id=GO:0051152 |text = positive regulation of smooth muscle cell differentiation}} {{GNF GO|id=GO:0051280 |text = negative regulation of release of sequestered calcium ion into cytosol}} {{GNF GO|id=GO:0051897 |text = positive regulation of protein kinase B signaling}} {{GNF GO|id=GO:0060312 |text = regulation of blood vessel remodeling}} {{GNF GO|id=GO:0060325 |text = face morphogenesis}} {{GNF GO|id=GO:0060364 |text = frontal suture morphogenesis}} {{GNF GO|id=GO:0060389 |text = pathway-restricted SMAD protein phosphorylation}} {{GNF GO|id=GO:0060391 |text = positive regulation of SMAD protein import into nucleus}} {{GNF GO|id=GO:0060395 |text = SMAD protein signal transduction}} {{GNF GO|id=GO:0060744 |text = mammary gland branching involved in thelarche}} {{GNF GO|id=GO:0060751 |text = branch elongation involved in mammary gland duct branching}} {{GNF GO|id=GO:0060762 |text = regulation of branching involved in mammary gland duct morphogenesis}} {{GNF GO|id=GO:0060965 |text = negative regulation of gene silencing by miRNA}} {{GNF GO|id=GO:0061035 |text = regulation of cartilage development}} {{GNF GO|id=GO:0070306 |text = lens fiber cell differentiation}} {{GNF GO|id=GO:0070723 |text = response to cholesterol}} {{GNF GO|id=GO:0071158 |text = positive regulation of cell cycle arrest}} {{GNF GO|id=GO:0071407 |text = cellular response to organic cyclic compound}} {{GNF GO|id=GO:0071549 |text = cellular response to dexamethasone stimulus}} {{GNF GO|id=GO:0071560 |text = cellular response to transforming growth factor beta stimulus}} {{GNF GO|id=GO:0085029 |text = extracellular matrix assembly}} {{GNF GO|id=GO:0090190 |text = positive regulation of branching involved in ureteric bud morphogenesis}} {{GNF GO|id=GO:0097191 |text = extrinsic apoptotic signaling pathway}} {{GNF GO|id=GO:1900126 |text = negative regulation of hyaluronan biosynthetic process}} {{GNF GO|id=GO:1901203 |text = positive regulation of extracellular matrix assembly}} {{GNF GO|id=GO:1901666 |text = positive regulation of NAD+ ADP-ribosyltransferase activity}} {{GNF GO|id=GO:2000249 |text = regulation of actin cytoskeleton reorganization}} {{GNF GO|id=GO:2000679 |text = positive regulation of transcription regulatory region DNA binding}}
| Hs_EntrezGene = 7040
| Hs_Ensembl = ENSG00000105329
| Hs_RefseqmRNA = NM_000660
| Hs_RefseqProtein = NP_000651
| Hs_GenLoc_db = hg38
| Hs_GenLoc_chr = 19
| Hs_GenLoc_start = 41301587
| Hs_GenLoc_end = 41353911
| Hs_Uniprot = P01137
| Mm_EntrezGene = 21803
| Mm_Ensembl = ENSMUSG00000002603
| Mm_RefseqmRNA = NM_011577
| Mm_RefseqProtein = NP_035707
| Mm_GenLoc_db = mm10
| Mm_GenLoc_chr = 7
| Mm_GenLoc_start = 25687002
| Mm_GenLoc_end = 25705077
| Mm_Uniprot = P04202
| path = PBB/7040
}}<noinclude>
[[تصنيف:قوالب بأسماء أجنبية]]
</noinclude>

قالب:PBB/7040 - تاريخ المراجعة

عبد العزيز: بوت: تصنيف القالب