عبد العزيز: بوت: تصنيف القالب

2018-11-21T17:57:12Z

بوت: تصنيف القالب

صفحة جديدة

{{GNF_Protein_box
| Name = Synuclein, alpha (non A4 component of amyloid precursor)
| image =
| image_source = [[بنك بيانات البروتينات]] rendering based on {{PDBe|1xq8}}<ref>{{Cite journal| vauthors = Ulmer TS, Bax A, Cole NB, Nussbaum RL | title = Structure and dynamics of micelle-bound human alpha-synuclein | journal = The Journal of Biological Chemistry | volume = 280 | issue = 10 | pages = 9595–603 | date = Mar 2005 | pmid = 15615727 | pmc = | doi = 10.1074/jbc.M411805200 }}</ref>.
| PDB = {{PDB2|1XQ8}}, {{PDB2|2JN5}}, {{PDB2|2KKW}}, {{PDB2|2M55}}, {{PDB2|2X6M}}, {{PDB2|3Q25}}, {{PDB2|3Q26}}, {{PDB2|3Q27}}, {{PDB2|3Q28}}, {{PDB2|3Q29}}, {{PDB2|4BXL}}, {{PDB2|4R0U}}, {{PDB2|4R0W}}
| HGNCid = 11138
| MGIid = 1277151
| Symbol = SNCA
| AltSymbols =; NACP; PARK1; PARK4; PD1
| IUPHAR =
| ChEMBL = 6152
| OMIM = 163890
| ECnumber =
| Homologene = 293
| GeneAtlas_image1 = PBB_GE_SNCA_204466_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_SNCA_204467_s_at_tn.png

| GeneAtlas_image3 =
| Protein_domain_image =
| Function = {{GNF GO|id=GO:0000287 |text = magnesium ion binding}} {{GNF GO|id=GO:0005504 |text = fatty acid binding}} {{GNF GO|id=GO:0005507 |text = copper ion binding}} {{GNF GO|id=GO:0005509 |text = calcium ion binding}} {{GNF GO|id=GO:0005515 |text = protein binding}} {{GNF GO|id=GO:0005543 |text = phospholipid binding}} {{GNF GO|id=GO:0008017 |text = microtubule binding}} {{GNF GO|id=GO:0008198 |text = ferrous iron binding}} {{GNF GO|id=GO:0008270 |text = zinc ion binding}} {{GNF GO|id=GO:0016491 |text = oxidoreductase activity}} {{GNF GO|id=GO:0019894 |text = kinesin binding}} {{GNF GO|id=GO:0019904 |text = protein domain specific binding}} {{GNF GO|id=GO:0042393 |text = histone binding}} {{GNF GO|id=GO:0042802 |text = identical protein binding}} {{GNF GO|id=GO:0043014 |text = alpha-tubulin binding}} {{GNF GO|id=GO:0043027 |text = cysteine-type endopeptidase inhibitor activity involved in apoptotic process}} {{GNF GO|id=GO:0043274 |text = phospholipase binding}} {{GNF GO|id=GO:0044212 |text = transcription regulatory region DNA binding}} {{GNF GO|id=GO:0045502 |text = dynein binding}} {{GNF GO|id=GO:0047485 |text = protein N-terminus binding}} {{GNF GO|id=GO:0048156 |text = tau protein binding}} {{GNF GO|id=GO:0048487 |text = beta-tubulin binding}} {{GNF GO|id=GO:0051219 |text = phosphoprotein binding}} {{GNF GO|id=GO:0060961 |text = phospholipase D inhibitor activity}}
| Component = {{GNF GO|id=GO:0005576 |text = extracellular region}} {{GNF GO|id=GO:0005615 |text = extracellular space}} {{GNF GO|id=GO:0005634 |text = nucleus}} {{GNF GO|id=GO:0005640 |text = nuclear outer membrane}} {{GNF GO|id=GO:0005737 |text = cytoplasm}} {{GNF GO|id=GO:0005739 |text = mitochondrion}} {{GNF GO|id=GO:0005747 |text = mitochondrial respiratory chain complex I}} {{GNF GO|id=GO:0005764 |text = lysosome}} {{GNF GO|id=GO:0005791 |text = rough endoplasmic reticulum}} {{GNF GO|id=GO:0005794 |text = Golgi apparatus}} {{GNF GO|id=GO:0005829 |text = cytosol}} {{GNF GO|id=GO:0005840 |text = ribosome}} {{GNF GO|id=GO:0005886 |text = plasma membrane}} {{GNF GO|id=GO:0005938 |text = cell cortex}} {{GNF GO|id=GO:0008021 |text = synaptic vesicle}} {{GNF GO|id=GO:0015629 |text = actin cytoskeleton}} {{GNF GO|id=GO:0016020 |text = membrane}} {{GNF GO|id=GO:0016234 |text = inclusion body}} {{GNF GO|id=GO:0030054 |text = cell junction}} {{GNF GO|id=GO:0030424 |text = axon}} {{GNF GO|id=GO:0030426 |text = growth cone}} {{GNF GO|id=GO:0031092 |text = platelet alpha granule membrane}} {{GNF GO|id=GO:0043195 |text = terminal bouton}} {{GNF GO|id=GO:0043205 |text = fibril}} {{GNF GO|id=GO:0048471 |text = perinuclear region of cytoplasm}}
| Process = {{GNF GO|id=GO:0000122 |text = negative regulation of transcription from RNA polymerase II promoter}} {{GNF GO|id=GO:0001774 |text = microglial cell activation}} {{GNF GO|id=GO:0001921 |text = positive regulation of receptor recycling}} {{GNF GO|id=GO:0001933 |text = negative regulation of protein phosphorylation}} {{GNF GO|id=GO:0001956 |text = positive regulation of neurotransmitter secretion}} {{GNF GO|id=GO:0006631 |text = fatty acid metabolic process}} {{GNF GO|id=GO:0006638 |text = neutral lipid metabolic process}} {{GNF GO|id=GO:0006644 |text = phospholipid metabolic process}} {{GNF GO|id=GO:0006919 |text = activation of cysteine-type endopeptidase activity involved in apoptotic process}} {{GNF GO|id=GO:0007006 |text = mitochondrial membrane organization}} {{GNF GO|id=GO:0007568 |text = aging}} {{GNF GO|id=GO:0008344 |text = adult locomotory behavior}} {{GNF GO|id=GO:0010040 |text = response to iron(II) ion}} {{GNF GO|id=GO:0010517 |text = regulation of phospholipase activity}} {{GNF GO|id=GO:0010642 |text = negative regulation of platelet-derived growth factor receptor signaling pathway}} {{GNF GO|id=GO:0014048 |text = regulation of glutamate secretion}} {{GNF GO|id=GO:0014059 |text = regulation of dopamine secretion}} {{GNF GO|id=GO:0031115 |text = negative regulation of microtubule polymerization}} {{GNF GO|id=GO:0031623 |text = receptor internalization}} {{GNF GO|id=GO:0031648 |text = protein destabilization}} {{GNF GO|id=GO:0032026 |text = response to magnesium ion}} {{GNF GO|id=GO:0032410 |text = negative regulation of transporter activity}} {{GNF GO|id=GO:0032496 |text = response to lipopolysaccharide}} {{GNF GO|id=GO:0032769 |text = negative regulation of monooxygenase activity}} {{GNF GO|id=GO:0033138 |text = positive regulation of peptidyl-serine phosphorylation}} {{GNF GO|id=GO:0034341 |text = response to interferon-gamma}} {{GNF GO|id=GO:0034599 |text = cellular response to oxidative stress}} {{GNF GO|id=GO:0035067 |text = negative regulation of histone acetylation}} {{GNF GO|id=GO:0040012 |text = regulation of locomotion}} {{GNF GO|id=GO:0042416 |text = dopamine biosynthetic process}} {{GNF GO|id=GO:0042493 |text = response to drug}} {{GNF GO|id=GO:0042775 |text = mitochondrial ATP synthesis coupled electron transport}} {{GNF GO|id=GO:0043030 |text = regulation of macrophage activation}} {{GNF GO|id=GO:0043065 |text = positive regulation of apoptotic process}} {{GNF GO|id=GO:0043066 |text = negative regulation of apoptotic process}} {{GNF GO|id=GO:0043154 |text = negative regulation of cysteine-type endopeptidase activity involved in apoptotic process}} {{GNF GO|id=GO:0043206 |text = extracellular fibril organization}} {{GNF GO|id=GO:0043524 |text = negative regulation of neuron apoptotic process}} {{GNF GO|id=GO:0044344 |text = cellular response to fibroblast growth factor stimulus}} {{GNF GO|id=GO:0045807 |text = positive regulation of endocytosis}} {{GNF GO|id=GO:0045920 |text = negative regulation of exocytosis}} {{GNF GO|id=GO:0045963 |text = negative regulation of dopamine metabolic process}} {{GNF GO|id=GO:0048148 |text = behavioral response to cocaine}} {{GNF GO|id=GO:0048169 |text = regulation of long-term neuronal synaptic plasticity}} {{GNF GO|id=GO:0048488 |text = synaptic vesicle endocytosis}} {{GNF GO|id=GO:0050808 |text = synapse organization}} {{GNF GO|id=GO:0050812 |text = regulation of acyl-CoA biosynthetic process}} {{GNF GO|id=GO:0051281 |text = positive regulation of release of sequestered calcium ion into cytosol}} {{GNF GO|id=GO:0051583 |text = dopamine uptake involved in synaptic transmission}} {{GNF GO|id=GO:0051585 |text = negative regulation of dopamine uptake involved in synaptic transmission}} {{GNF GO|id=GO:0051612 |text = negative regulation of serotonin uptake}} {{GNF GO|id=GO:0051622 |text = negative regulation of norepinephrine uptake}} {{GNF GO|id=GO:0055074 |text = calcium ion homeostasis}} {{GNF GO|id=GO:0055114 |text = oxidation-reduction process}} {{GNF GO|id=GO:0060079 |text = regulation of excitatory postsynaptic membrane potential}} {{GNF GO|id=GO:0060291 |text = long-term synaptic potentiation}} {{GNF GO|id=GO:0060732 |text = positive regulation of inositol phosphate biosynthetic process}} {{GNF GO|id=GO:0070495 |text = negative regulation of thrombin receptor signaling pathway}} {{GNF GO|id=GO:0070555 |text = response to interleukin-1}} {{GNF GO|id=GO:0071280 |text = cellular response to copper ion}} {{GNF GO|id=GO:0071872 |text = cellular response to epinephrine stimulus}} {{GNF GO|id=GO:0071902 |text = positive regulation of protein serine/threonine kinase activity}} {{GNF GO|id=GO:1902957 |text = negative regulation of mitochondrial electron transport, NADH to ubiquinone}} {{GNF GO|id=GO:1903284 |text = positive regulation of glutathione peroxidase activity}} {{GNF GO|id=GO:1903285 |text = positive regulation of hydrogen peroxide catabolic process}} {{GNF GO|id=GO:1903421 |text = regulation of synaptic vesicle recycling}} {{GNF GO|id=GO:1903426 |text = regulation of reactive oxygen species biosynthetic process}}
| Hs_EntrezGene = 6622
| Hs_Ensembl = ENSG00000145335
| Hs_RefseqmRNA = NM_000345
| Hs_RefseqProtein = NP_000336
| Hs_GenLoc_db = hg38
| Hs_GenLoc_chr = 4
| Hs_GenLoc_start = 89724099
| Hs_GenLoc_end = 89838315
| Hs_Uniprot = P37840
| Mm_EntrezGene = 20617
| Mm_Ensembl = ENSMUSG00000025889
| Mm_RefseqmRNA = NM_001042451
| Mm_RefseqProtein = NP_001035916
| Mm_GenLoc_db = mm10
| Mm_GenLoc_chr = 6
| Mm_GenLoc_start = 60731573
| Mm_GenLoc_end = 60829855
| Mm_Uniprot = O55042
| path = PBB/6622
}}<noinclude>
{{مراجع}}
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[[تصنيف:قوالب بأسماء أجنبية]]
</noinclude>

قالب:PBB/6622 - تاريخ المراجعة

عبد العزيز: بوت: تصنيف القالب