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قالب:PBB/5624 - تاريخ المراجعة
2026-06-06T08:18:53Z
تاريخ التعديل لهذه الصفحة في الويكي
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عبد العزيز: بوت: إصلاح التحويلات
2022-02-17T10:46:57Z
<p>بوت: إصلاح التحويلات</p>
<p><b>صفحة جديدة</b></p><div>{{GNF_Protein_box<br />
| image = Protein_PROC_PDB_1aut.png<br />
| image_source = [[بنية جزيئية حيوية]] of human activated protein C (minus the [[Gla domain|Gla-domain]]{{محتوى مرجعي|α}}), determined by [[دراسة البلورات بالأشعة السينية#Biological_macromolecular_crystallography|X-ray crystallography]] (Heavy chain on the left and light chain to the right; each chain is individually rainbow colored, [[نهاية أمينية|طرف أميني]] = blue, [[نهاية كربوكسيلية|طرف كربوكسيلي]] = red.)<ref name=mather>{{PDB|1AUT}}; {{cite journal | author = Mather T, Oganessyan V, Hof P, Huber R, Foundling S, Esmon C, Bode W | title = The 2.8 Å crystal structure of Gla-domainless activated protein C | journal = EMBO J. | volume = 15 | issue = 24 | pages = 6822–31 | date=December 1996 | pmid = 9003757 | pmc = 452507 | doi = | url = | issn = }}</ref><ref name=pymolwiki>{{استشهاد ويب<br />
| last = PyMOLWiki Contributors<br />
| title = Advanced Coloring<br />
| work = PyMOLWiki<br />
| accessdate = 2010-09-14<br />
| date = 2010-05-17<br />
| url = http://www.pymolwiki.org/index.php?title=Advanced_Coloring&oldid=8253<br />
}}</ref><br />
| PDB = [http://www.ebi.ac.uk/pdbe/searchResults.html?display=both&term={{Homologene2PDBe|37288}} PDBe], [http://www.rcsb.org/pdb/search/smartSubquery.do?smartSearchSubtype=UpAccessionIdQuery&accessionIdList={{Homologene2uniprot|37288}} RCSB]<br />
| Name = Protein C (inactivator of coagulation factors Va and VIIIa)<br />
| HGNCid = 9451<br />
| Symbol = PROC<br />
| AltSymbols =; PROC1<br />
| IUPHAR = yes<br />
| ChEMBL = <br />
| OMIM = 176860<br />
| ECnumber = 3.4.21.69<br />
| Homologene = 37288<br />
| MGIid = 97771<br />
| GeneAtlas_image1 = PBB_GE_PROC_206259_at_tn.png<br />
| Function = {{GNF_GO|id=GO:0003808 |text = protein C (activated) activity}} {{GNF_GO|id=GO:0005509 |text = calcium ion binding}} {{GNF_GO|id=GO:0008233 |text = peptidase activity}} <br />
| Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}} <br />
| Process = {{GNF_GO|id=GO:0006508 |text = proteolysis}} {{GNF_GO|id=GO:0007596 |text = blood coagulation}} {{GNF_GO|id=GO:0030195 |text = negative regulation of blood coagulation}} {{GNF_GO|id=GO:0043066 |text = negative regulation of apoptosis}} <br />
| Hs_EntrezGene = 5624<br />
| Hs_Ensembl = ENSG00000115718<br />
| Hs_RefseqProtein = NP_000303<br />
| Hs_RefseqmRNA = NM_000312<br />
| Hs_GenLoc_db = hg18<br />
| Hs_GenLoc_chr = 2<br />
| Hs_GenLoc_start = 127892486<br />
| Hs_GenLoc_end = 127903288<br />
| Hs_Uniprot = P04070<br />
| Mm_EntrezGene = 19123<br />
| Mm_Ensembl = ENSMUSG00000024386<br />
| Mm_RefseqmRNA = NM_008934<br />
| Mm_RefseqProtein = NP_032960<br />
| Mm_GenLoc_db = mm8<br />
| Mm_GenLoc_chr = 18<br />
| Mm_GenLoc_start = 32266137<br />
| Mm_GenLoc_end = 32281209<br />
| Mm_Uniprot = P33587<br />
| path = PBB/5624<br />
}}<br />
<noinclude>{{قائمة مراجع قالب}}</noinclude></div>
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