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قالب:PBB/2155 - تاريخ المراجعة
2026-06-05T19:21:15Z
تاريخ التعديل لهذه الصفحة في الويكي
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عبد العزيز: روبوت: استبدال قوالب: Reflist
2015-12-04T09:01:23Z
<p>روبوت: استبدال قوالب: Reflist</p>
<p><b>صفحة جديدة</b></p><div>{{GNF_Protein_box<br />
| Name = Coagulation factor VII (serum prothrombin conversion accelerator)<br />
| image = 1dan_opm.png<br />
| image_source = Anchoring of coagulation factor VIIa (PDB {{PDBe|1dan}}<ref name="pmid8598903">{{cite journal | author = Banner DW, D'Arcy A, Chène C, Winkler FK, Guha A, Konigsberg WH, Nemerson Y, Kirchhofer D | title = The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor | journal = Nature | volume = 380 | issue = 6569 | pages = 41–6 | year = 1996 | pmid = 8598903 | doi = 10.1038/380041a0 }}</ref>) to the membrane through its [[Gla domain]]<br />
| PDB = {{PDB2|1BF9}}, {{PDB2|1CVW}}, {{PDB2|1DAN}}, {{PDB2|1DVA}}, {{PDB2|1F7E}}, {{PDB2|1F7M}}, {{PDB2|1FAK}}, {{PDB2|1FF7}}, {{PDB2|1FFM}}, {{PDB2|1J9C}}, {{PDB2|1JBU}}, {{PDB2|1KLI}}, {{PDB2|1KLJ}}, {{PDB2|1NL8}}, {{PDB2|1O5D}}, {{PDB2|1QFK}}, {{PDB2|1W0Y}}, {{PDB2|1W2K}}, {{PDB2|1W7X}}, {{PDB2|1W8B}}, {{PDB2|1WQV}}, {{PDB2|1WSS}}, {{PDB2|1WTG}}, {{PDB2|1WUN}}, {{PDB2|1WV7}}, {{PDB2|1YGC}}, {{PDB2|1Z6J}}, {{PDB2|2A2Q}}, {{PDB2|2AEI}}, {{PDB2|2AER}}, {{PDB2|2B7D}}, {{PDB2|2B8O}}, {{PDB2|2BZ6}}, {{PDB2|2C4F}}, {{PDB2|2EC9}}, {{PDB2|2F9B}}, {{PDB2|2FIR}}, {{PDB2|2FLB}}, {{PDB2|2FLR}}, {{PDB2|2PUQ}}, {{PDB2|2ZP0}}, {{PDB2|2ZWL}}, {{PDB2|2ZZU}}, {{PDB2|3ELA}}, {{PDB2|3TH2}}, {{PDB2|3TH3}}, {{PDB2|3TH4}}, {{PDB2|4IBL}}, {{PDB2|4ISH}}, {{PDB2|4ISI}}, {{PDB2|4JYU}}, {{PDB2|4JYV}}, {{PDB2|4JZD}}, {{PDB2|4JZE}}, {{PDB2|4JZF}}, {{PDB2|4NA9}}, {{PDB2|4NG9}}, {{PDB2|4NGA}}, {{PDB2|4X8S}}, {{PDB2|4X8T}}, {{PDB2|4X8U}}, {{PDB2|4X8V}}, {{PDB2|4YT6}}, {{PDB2|4YT7}}<br />
| HGNCid = 3544<br />
| MGIid = 109325<br />
| Symbol = F7<br />
| AltSymbols =; SPCA<br />
| IUPHAR = <br />
| ChEMBL = 3991<br />
| OMIM = 613878<br />
| ECnumber = 3.4.21.21<br />
| Homologene = 7710<br />
| GeneAtlas_image1 = PBB_GE_F7_207300_s_at_tn.png<br />
| GeneAtlas_image2 = <br />
| GeneAtlas_image3 = <br />
| Protein_domain_image = <br />
| Function = {{GNF_GO|id=GO:0001948 |text = glycoprotein binding}} {{GNF_GO|id=GO:0004252 |text = serine-type endopeptidase activity}} {{GNF_GO|id=GO:0005102 |text = receptor binding}} {{GNF_GO|id=GO:0005509 |text = calcium ion binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008236 |text = serine-type peptidase activity}}<br />
| Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}} {{GNF_GO|id=GO:0005615 |text = extracellular space}} {{GNF_GO|id=GO:0005788 |text = endoplasmic reticulum lumen}} {{GNF_GO|id=GO:0005796 |text = Golgi lumen}} {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0031982 |text = vesicle}}<br />
| Process = {{GNF_GO|id=GO:0002690 |text = positive regulation of leukocyte chemotaxis}} {{GNF_GO|id=GO:0006508 |text = proteolysis}} {{GNF_GO|id=GO:0007596 |text = blood coagulation}} {{GNF_GO|id=GO:0007598 |text = blood coagulation, extrinsic pathway}} {{GNF_GO|id=GO:0007623 |text = circadian rhythm}} {{GNF_GO|id=GO:0010641 |text = positive regulation of platelet-derived growth factor receptor signaling pathway}} {{GNF_GO|id=GO:0017187 |text = peptidyl-glutamic acid carboxylation}} {{GNF_GO|id=GO:0030194 |text = positive regulation of blood coagulation}} {{GNF_GO|id=GO:0030335 |text = positive regulation of cell migration}} {{GNF_GO|id=GO:0031100 |text = organ regeneration}} {{GNF_GO|id=GO:0032571 |text = response to vitamin K}} {{GNF_GO|id=GO:0043627 |text = response to estrogen}} {{GNF_GO|id=GO:0043687 |text = post-translational protein modification}} {{GNF_GO|id=GO:0044267 |text = cellular protein metabolic process}} {{GNF_GO|id=GO:0050927 |text = positive regulation of positive chemotaxis}} {{GNF_GO|id=GO:0051897 |text = positive regulation of protein kinase B signaling}} {{GNF_GO|id=GO:0060416 |text = response to growth hormone}}<br />
| Hs_EntrezGene = 2155<br />
| Hs_Ensembl = ENSG00000057593<br />
| Hs_RefseqmRNA = NM_000131<br />
| Hs_RefseqProtein = NP_000122<br />
| Hs_GenLoc_db = hg38<br />
| Hs_GenLoc_chr = 13<br />
| Hs_GenLoc_start = 113105788<br />
| Hs_GenLoc_end = 113120681<br />
| Hs_Uniprot = P08709<br />
| Mm_EntrezGene = 14068<br />
| Mm_Ensembl = ENSMUSG00000031443<br />
| Mm_RefseqmRNA = NM_010172<br />
| Mm_RefseqProtein = NP_034302<br />
| Mm_GenLoc_db = mm10<br />
| Mm_GenLoc_chr = 8<br />
| Mm_GenLoc_start = 13026034<br />
| Mm_GenLoc_end = 13035809<br />
| Mm_Uniprot = P70375<br />
| path = PBB/2155<br />
}}<noinclude><br />
{{مراجع}}<br />
</noinclude></div>
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